442 related articles for article (PubMed ID: 16620699)
1. Role and mechanism of rosiglitazone on the impairment of insulin secretion induced by free fatty acids on isolated rat islets.
Tian JY; Li G; Gu YY; Zhang HL; Zhou WZ; Wang X; Zhu HD; Luo TH; Luo M
Chin Med J (Engl); 2006 Apr; 119(7):574-80. PubMed ID: 16620699
[TBL] [Abstract][Full Text] [Related]
2. Rosiglitazone prevents the impairment of human islet function induced by fatty acids: evidence for a role of PPARgamma2 in the modulation of insulin secretion.
Lupi R; Del Guerra S; Marselli L; Bugliani M; Boggi U; Mosca F; Marchetti P; Del Prato S
Am J Physiol Endocrinol Metab; 2004 Apr; 286(4):E560-7. PubMed ID: 14625208
[TBL] [Abstract][Full Text] [Related]
3. Role of ATP production and uncoupling protein-2 in the insulin secretory defect induced by chronic exposure to high glucose or free fatty acids and effects of peroxisome proliferator-activated receptor-gamma inhibition.
Patanè G; Anello M; Piro S; Vigneri R; Purrello F; Rabuazzo AM
Diabetes; 2002 Sep; 51(9):2749-56. PubMed ID: 12196468
[TBL] [Abstract][Full Text] [Related]
4. Rosiglitazone reverses insulin secretion altered by chronic exposure to free fatty acid via IRS-2-associated phosphatidylinositol 3-kinase pathway.
Yang L; An HX; Deng XL; Chen LL; Li ZY
Acta Pharmacol Sin; 2003 May; 24(5):429-34. PubMed ID: 12740178
[TBL] [Abstract][Full Text] [Related]
5. Induction of uncoupling protein 2 mRNA in beta-cells is stimulated by oxidation of fatty acids but not by nutrient oversupply.
Li LX; Skorpen F; Egeberg K; Jørgensen IH; Grill V
Endocrinology; 2002 Apr; 143(4):1371-7. PubMed ID: 11897694
[TBL] [Abstract][Full Text] [Related]
6. Metformin restores insulin secretion altered by chronic exposure to free fatty acids or high glucose: a direct metformin effect on pancreatic beta-cells.
Patanè G; Piro S; Rabuazzo AM; Anello M; Vigneri R; Purrello F
Diabetes; 2000 May; 49(5):735-40. PubMed ID: 10905481
[TBL] [Abstract][Full Text] [Related]
7. Peroxisome proliferator-activated receptor gamma coactivator-1-dependent uncoupling protein-2 expression in pancreatic islets of rats: a novel pathway for neural control of insulin secretion.
De Souza CT; Gasparetti AL; Pereira-da-Silva M; Araújo EP; Carvalheira JB; Saad MJ; Boschero AC; Carneiro EM; Velloso LA
Diabetologia; 2003 Nov; 46(11):1522-31. PubMed ID: 14576981
[TBL] [Abstract][Full Text] [Related]
8. Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle.
Zhou YP; Grill VE
J Clin Invest; 1994 Feb; 93(2):870-6. PubMed ID: 8113418
[TBL] [Abstract][Full Text] [Related]
9. Increased uncoupling protein-2 levels in beta-cells are associated with impaired glucose-stimulated insulin secretion: mechanism of action.
Chan CB; De Leo D; Joseph JW; McQuaid TS; Ha XF; Xu F; Tsushima RG; Pennefather PS; Salapatek AM; Wheeler MB
Diabetes; 2001 Jun; 50(6):1302-10. PubMed ID: 11375330
[TBL] [Abstract][Full Text] [Related]
10. GPR40 protein levels are crucial to the regulation of stimulated hormone secretion in pancreatic islets. Lessons from spontaneous obesity-prone and non-obese type 2 diabetes in rats.
Meidute Abaraviciene S; Muhammed SJ; Amisten S; Lundquist I; Salehi A
Mol Cell Endocrinol; 2013 Dec; 381(1-2):150-9. PubMed ID: 23911664
[TBL] [Abstract][Full Text] [Related]
11. PPAR-gamma overexpression selectively suppresses insulin secretory capacity in isolated pancreatic islets through induction of UCP-2 protein.
Ito E; Ozawa S; Takahashi K; Tanaka T; Katsuta H; Yamaguchi S; Maruyama M; Takizawa M; Katahira H; Yoshimoto K; Nagamatsu S; Ishida H
Biochem Biophys Res Commun; 2004 Nov; 324(2):810-4. PubMed ID: 15474499
[TBL] [Abstract][Full Text] [Related]
12. Free fatty acid-induced beta-cell defects are dependent on uncoupling protein 2 expression.
Joseph JW; Koshkin V; Saleh MC; Sivitz WI; Zhang CY; Lowell BB; Chan CB; Wheeler MB
J Biol Chem; 2004 Dec; 279(49):51049-56. PubMed ID: 15448158
[TBL] [Abstract][Full Text] [Related]
13. Peroxisome proliferator-activated receptor alpha (PPARalpha) potentiates, whereas PPARgamma attenuates, glucose-stimulated insulin secretion in pancreatic beta-cells.
Ravnskjaer K; Boergesen M; Rubi B; Larsen JK; Nielsen T; Fridriksson J; Maechler P; Mandrup S
Endocrinology; 2005 Aug; 146(8):3266-76. PubMed ID: 15878969
[TBL] [Abstract][Full Text] [Related]
14. Contrasting effects of nateglinide and rosiglitazone on insulin secretion and phospholipase C activation.
Zawalich WS; Tesz G; Zawalich KC
Metabolism; 2003 Nov; 52(11):1393-9. PubMed ID: 14624396
[TBL] [Abstract][Full Text] [Related]
15. Palmitate impairs and eicosapentaenoate restores insulin secretion through regulation of SREBP-1c in pancreatic islets.
Kato T; Shimano H; Yamamoto T; Ishikawa M; Kumadaki S; Matsuzaka T; Nakagawa Y; Yahagi N; Nakakuki M; Hasty AH; Takeuchi Y; Kobayashi K; Takahashi A; Yatoh S; Suzuki H; Sone H; Yamada N
Diabetes; 2008 Sep; 57(9):2382-92. PubMed ID: 18458149
[TBL] [Abstract][Full Text] [Related]
16. Regulation of insulin secretion and expression of SUR1 gene by chronic exposure to free fatty acids in rat pancreatic beta cells.
Yuan L; Deng X; Chen L; Zhou M
J Huazhong Univ Sci Technolog Med Sci; 2004; 24(4):358-60, 364. PubMed ID: 15587398
[TBL] [Abstract][Full Text] [Related]
17. Effects of free fatty acids on beta-cell functions: a possible involvement of peroxisome proliferator-activated receptors alpha or pancreatic/duodenal homeobox.
Yoshikawa H; Tajiri Y; Sako Y; Hashimoto T; Umeda F; Nawata H
Metabolism; 2001 May; 50(5):613-8. PubMed ID: 11319727
[TBL] [Abstract][Full Text] [Related]
18. Overexpression of uncoupling protein 2 inhibits glucose-stimulated insulin secretion from rat islets.
Chan CB; MacDonald PE; Saleh MC; Johns DC; Marbàn E; Wheeler MB
Diabetes; 1999 Jul; 48(7):1482-6. PubMed ID: 10389858
[TBL] [Abstract][Full Text] [Related]
19. Differential effects of hyperlipidemia on insulin secretion in islets of langerhans from hyperglycemic versus normoglycemic rats.
Briaud I; Kelpe CL; Johnson LM; Tran PO; Poitout V
Diabetes; 2002 Mar; 51(3):662-8. PubMed ID: 11872664
[TBL] [Abstract][Full Text] [Related]
20. Augmentation of Ca2+-stimulated insulin release by glucose and long-chain fatty acids in rat pancreatic islets: free fatty acids mimic ATP-sensitive K+ channel-independent insulinotropic action of glucose.
Komatsu M; Yajima H; Yamada S; Kaneko T; Sato Y; Yamauchi K; Hashizume K; Aizawa T
Diabetes; 1999 Aug; 48(8):1543-9. PubMed ID: 10426371
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]