BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

59 related articles for article (PubMed ID: 16620770)

  • 1. Effect of construct design on MAPKAP kinase-2 activity, thermodynamic stability and ligand-binding affinity.
    Kervinen J; Ma H; Bayoumy S; Schubert C; Milligan C; Lewandowski F; Moriarty K; Desjarlais RL; Ramachandren K; Wang H; Harris CA; Grasberger B; Todd M; Springer BA; Deckman I
    Arch Biochem Biophys; 2006 May; 449(1-2):47-56. PubMed ID: 16620770
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Catalysis and function of the p38 alpha.MK2a signaling complex.
    Lukas SM; Kroe RR; Wildeson J; Peet GW; Frego L; Davidson W; Ingraham RH; Pargellis CA; Labadia ME; Werneburg BG
    Biochemistry; 2004 Aug; 43(31):9950-60. PubMed ID: 15287722
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Thermodynamic stability of carbonic anhydrase: measurements of binding affinity and stoichiometry using ThermoFluor.
    Matulis D; Kranz JK; Salemme FR; Todd MJ
    Biochemistry; 2005 Apr; 44(13):5258-66. PubMed ID: 15794662
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural analysis of carboline derivatives as inhibitors of MAPKAP K2 using 3D QSAR and docking studies.
    Nayana RS; Bommisetty SK; Singh K; Bairy SK; Nunna S; Pramod A; Muttineni R
    J Chem Inf Model; 2009 Jan; 49(1):53-67. PubMed ID: 19119997
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The C-terminal domain of Mnk1a plays a dual role in tightly regulating its activity.
    Goto S; Yao Z; Proud CG
    Biochem J; 2009 Sep; 423(2):279-90. PubMed ID: 19650764
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Genistein inhibits matrix metalloproteinase type 2 activation and prostate cancer cell invasion by blocking the transforming growth factor beta-mediated activation of mitogen-activated protein kinase-activated protein kinase 2-27-kDa heat shock protein pathway.
    Xu L; Bergan RC
    Mol Pharmacol; 2006 Sep; 70(3):869-77. PubMed ID: 16772519
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ligand binding affinity determined by temperature-dependent circular dichroism: cyclin-dependent kinase 2 inhibitors.
    Mayhood TW; Windsor WT
    Anal Biochem; 2005 Oct; 345(2):187-97. PubMed ID: 16140252
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Development and implementation of three mitogen-activated protein kinase (MAPK) signaling pathway imaging assays to provide MAPK module selectivity profiling for kinase inhibitors: MK2-EGFP translocation, c-Jun, and ERK activation.
    Nickischer D; Laethem C; Trask OJ; Williams RG; Kandasamy R; Johnston PA; Johnston PA
    Methods Enzymol; 2006; 414():389-418. PubMed ID: 17110204
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of RhoA/Rho-kinase pathway suppresses the expression of type I collagen induced by TGF-beta2 in human retinal pigment epithelial cells.
    Itoh Y; Kimoto K; Imaizumi M; Nakatsuka K
    Exp Eye Res; 2007 Mar; 84(3):464-72. PubMed ID: 17217948
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The signalling profile of recombinant human orexin-2 receptor.
    Tang J; Chen J; Ramanjaneya M; Punn A; Conner AC; Randeva HS
    Cell Signal; 2008 Sep; 20(9):1651-61. PubMed ID: 18599270
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Thermal denaturation: a method to rank slow binding, high-affinity P38alpha MAP kinase inhibitors.
    Kroe RR; Regan J; Proto A; Peet GW; Roy T; Landro LD; Fuschetto NG; Pargellis CA; Ingraham RH
    J Med Chem; 2003 Oct; 46(22):4669-75. PubMed ID: 14561086
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pyrrolopyridine inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2).
    Anderson DR; Meyers MJ; Vernier WF; Mahoney MW; Kurumbail RG; Caspers N; Poda GI; Schindler JF; Reitz DB; Mourey RJ
    J Med Chem; 2007 May; 50(11):2647-54. PubMed ID: 17480064
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Distinct role of MAPKAPK-2 in the regulation of TNF gene expression by Toll-like receptor 7 and 9 ligands.
    Thuraisingam T; Xu YZ; Moisan J; Lachance C; Garnon J; Di Marco S; Gaestel M; Radzioch D
    Mol Immunol; 2007 Jul; 44(14):3482-91. PubMed ID: 17485113
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of SAD kinase by Ca2+/calmodulin-dependent protein kinase kinase.
    Fujimoto T; Yurimoto S; Hatano N; Nozaki N; Sueyoshi N; Kameshita I; Mizutani A; Mikoshiba K; Kobayashi R; Tokumitsu H
    Biochemistry; 2008 Apr; 47(13):4151-9. PubMed ID: 18324781
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identifying protein construct variants with increased crystallization propensity--a case study.
    Malawski GA; Hillig RC; Monteclaro F; Eberspaecher U; Schmitz AA; Crusius K; Huber M; Egner U; Donner P; Müller-Tiemann B
    Protein Sci; 2006 Dec; 15(12):2718-28. PubMed ID: 17132859
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural basis for a high affinity inhibitor bound to protein kinase MK2.
    Hillig RC; Eberspaecher U; Monteclaro F; Huber M; Nguyen D; Mengel A; Muller-Tiemann B; Egner U
    J Mol Biol; 2007 Jun; 369(3):735-45. PubMed ID: 17449059
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Femtomolar Zn(II) affinity in a peptide-based ligand designed to model thiolate-rich metalloprotein active sites.
    Petros AK; Reddi AR; Kennedy ML; Hyslop AG; Gibney BR
    Inorg Chem; 2006 Dec; 45(25):9941-58. PubMed ID: 17140191
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tumor necrosis factor-alpha up-regulates the expression of CCL2 and adhesion molecules of human proximal tubular epithelial cells through MAPK signaling pathways.
    Ho AW; Wong CK; Lam CW
    Immunobiology; 2008; 213(7):533-44. PubMed ID: 18656701
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Control of mRNA decay by phosphorylation of tristetraprolin.
    Sandler H; Stoecklin G
    Biochem Soc Trans; 2008 Jun; 36(Pt 3):491-6. PubMed ID: 18481987
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Transcriptional activation of c-Fos by constitutively active Galpha(16)QL through a STAT1-dependent pathway.
    Lo RK; Wong YH
    Cell Signal; 2006 Dec; 18(12):2143-53. PubMed ID: 16781847
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 3.