BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

138 related articles for article (PubMed ID: 16621545)

  • 1. Synthesis of Hsp90 dimerization modulators.
    Chiosis G; Aguirre J; Nicchitta CV
    Bioorg Med Chem Lett; 2006 Jul; 16(13):3529-32. PubMed ID: 16621545
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and biological evaluation of a new class of geldanamycin derivatives as potent inhibitors of Hsp90.
    Le Brazidec JY; Kamal A; Busch D; Thao L; Zhang L; Timony G; Grecko R; Trent K; Lough R; Salazar T; Khan S; Burrows F; Boehm MF
    J Med Chem; 2004 Jul; 47(15):3865-73. PubMed ID: 15239664
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure-based design of 7-carbamate analogs of geldanamycin.
    Rastelli G; Tian ZQ; Wang Z; Myles D; Liu Y
    Bioorg Med Chem Lett; 2005 Nov; 15(22):5016-21. PubMed ID: 16165354
    [TBL] [Abstract][Full Text] [Related]  

  • 4. [Heat shock protein 90: novel target for cancer therapy].
    Chen Y; Ding J
    Ai Zheng; 2004 Aug; 23(8):968-74. PubMed ID: 15301726
    [TBL] [Abstract][Full Text] [Related]  

  • 5. [Advances in antitumor activity of the hsp90 inhibitor geldanamycin].
    Liao ZY; Zhen YS
    Yao Xue Xue Bao; 2001 Sep; 36(9):716-20. PubMed ID: 12580116
    [No Abstract]   [Full Text] [Related]  

  • 6. Synthesis and biological activities of novel 17-aminogeldanamycin derivatives.
    Tian ZQ; Liu Y; Zhang D; Wang Z; Dong SD; Carreras CW; Zhou Y; Rastelli G; Santi DV; Myles DC
    Bioorg Med Chem; 2004 Oct; 12(20):5317-29. PubMed ID: 15388159
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Biotinylated geldanamycin.
    Clevenger RC; Raibel JM; Peck AM; Blagg BS
    J Org Chem; 2004 Jun; 69(13):4375-80. PubMed ID: 15202892
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis of a red-shifted fluorescence polarization probe for Hsp90.
    Moulick K; Clement CC; Aguirre J; Kim J; Kang Y; Felts S; Chiosis G
    Bioorg Med Chem Lett; 2006 Sep; 16(17):4515-8. PubMed ID: 16797988
    [TBL] [Abstract][Full Text] [Related]  

  • 9. NMR backbone assignment of the N-terminal domain of human HSP90.
    Jacobs DM; Langer T; Elshorst B; Saxena K; Fiebig KM; Vogtherr M; Schwalbe H
    J Biomol NMR; 2006; 36 Suppl 1():52. PubMed ID: 16821127
    [No Abstract]   [Full Text] [Related]  

  • 10. Design, synthesis, and biological evaluation of hydroquinone derivatives of 17-amino-17-demethoxygeldanamycin as potent, water-soluble inhibitors of Hsp90.
    Ge J; Normant E; Porter JR; Ali JA; Dembski MS; Gao Y; Georges AT; Grenier L; Pak RH; Patterson J; Sydor JR; Tibbitts TT; Tong JK; Adams J; Palombella VJ
    J Med Chem; 2006 Jul; 49(15):4606-15. PubMed ID: 16854066
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Biosynthesis of the heat-shock protein 90 inhibitor geldanamycin: new insight into the formation of the benzoquinone moiety.
    Lee D; Lee K; Cai XF; Dat NT; Boovanahalli SK; Lee M; Shin JC; Kim W; Jeong JK; Lee JS; Lee CH; Lee JH; Hong YS; Lee JJ
    Chembiochem; 2006 Feb; 7(2):246-8. PubMed ID: 16381049
    [No Abstract]   [Full Text] [Related]  

  • 12. Heat shock protein-90 inhibitors: a chronicle from geldanamycin to today's agents.
    Chiosis G; Caldas Lopes E; Solit D
    Curr Opin Investig Drugs; 2006 Jun; 7(6):534-41. PubMed ID: 16784024
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In vitro evidence that hsp90 contains two independent chaperone sites.
    Young JC; Schneider C; Hartl FU
    FEBS Lett; 1997 Nov; 418(1-2):139-43. PubMed ID: 9414113
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Quantum chemical calculations and mutational analysis suggest heat shock protein 90 catalyzes trans-cis isomerization of geldanamycin.
    Lee YS; Marcu MG; Neckers L
    Chem Biol; 2004 Jul; 11(7):991-8. PubMed ID: 15271357
    [TBL] [Abstract][Full Text] [Related]  

  • 15. [Hsp90: how a chaperone becomes a pharmacological target].
    Jacquemin-Sablon A
    Bull Cancer; 2003 Nov; 90(11):935-6. PubMed ID: 14706894
    [No Abstract]   [Full Text] [Related]  

  • 16. Total synthesis of herbimycin A.
    Carter KD; Panek JS
    Org Lett; 2004 Jan; 6(1):55-7. PubMed ID: 14703349
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Heat shock protein 90 inhibitors. A text book example of medicinal chemistry?
    Janin YL
    J Med Chem; 2005 Dec; 48(24):7503-12. PubMed ID: 16302791
    [No Abstract]   [Full Text] [Related]  

  • 18. LY294002-geldanamycin heterodimers as selective inhibitors of the PI3K and PI3K-related family.
    Chiosis G; Rosen N; Sepp-Lorenzino L
    Bioorg Med Chem Lett; 2001 Apr; 11(7):909-13. PubMed ID: 11294389
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Geldanamycin analogs.
    Sausville EA
    J Chemother; 2004 Nov; 16 Suppl 4():68-9. PubMed ID: 15688614
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tanespimycin: the opportunities and challenges of targeting heat shock protein 90.
    Erlichman C
    Expert Opin Investig Drugs; 2009 Jun; 18(6):861-8. PubMed ID: 19466875
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.