BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

428 related articles for article (PubMed ID: 16622404)

  • 1. Two-step activation of ATM by DNA and the Mre11-Rad50-Nbs1 complex.
    Dupré A; Boyer-Chatenet L; Gautier J
    Nat Struct Mol Biol; 2006 May; 13(5):451-7. PubMed ID: 16622404
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ataxia telangiectasia-mutated (ATM) kinase activity is regulated by ATP-driven conformational changes in the Mre11/Rad50/Nbs1 (MRN) complex.
    Lee JH; Mand MR; Deshpande RA; Kinoshita E; Yang SH; Wyman C; Paull TT
    J Biol Chem; 2013 May; 288(18):12840-51. PubMed ID: 23525106
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Mre11/Rad50/Nbs1 complex and its role as a DNA double-strand break sensor for ATM.
    Paull TT; Lee JH
    Cell Cycle; 2005 Jun; 4(6):737-40. PubMed ID: 15908798
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template.
    Williams RS; Williams JS; Tainer JA
    Biochem Cell Biol; 2007 Aug; 85(4):509-20. PubMed ID: 17713585
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activation and regulation of ATM kinase activity in response to DNA double-strand breaks.
    Lee JH; Paull TT
    Oncogene; 2007 Dec; 26(56):7741-8. PubMed ID: 18066086
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex.
    Lee JH; Paull TT
    Science; 2005 Apr; 308(5721):551-4. PubMed ID: 15790808
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The carboxy terminus of NBS1 is required for induction of apoptosis by the MRE11 complex.
    Stracker TH; Morales M; Couto SS; Hussein H; Petrini JH
    Nature; 2007 May; 447(7141):218-21. PubMed ID: 17429352
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Active role for nibrin in the kinetics of atm activation.
    Cerosaletti K; Wright J; Concannon P
    Mol Cell Biol; 2006 Mar; 26(5):1691-9. PubMed ID: 16478990
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Purification and biochemical characterization of ataxia-telangiectasia mutated and Mre11/Rad50/Nbs1.
    Lee JH; Paull TT
    Methods Enzymol; 2006; 408():529-39. PubMed ID: 16793391
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Independent roles for nibrin and Mre11-Rad50 in the activation and function of Atm.
    Cerosaletti K; Concannon P
    J Biol Chem; 2004 Sep; 279(37):38813-9. PubMed ID: 15234984
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity.
    Jazayeri A; Balestrini A; Garner E; Haber JE; Costanzo V
    EMBO J; 2008 Jul; 27(14):1953-62. PubMed ID: 18596698
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cell cycle-dependent role of MRN at dysfunctional telomeres: ATM signaling-dependent induction of nonhomologous end joining (NHEJ) in G1 and resection-mediated inhibition of NHEJ in G2.
    Dimitrova N; de Lange T
    Mol Cell Biol; 2009 Oct; 29(20):5552-63. PubMed ID: 19667071
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ATM and the Mre11-Rad50-Nbs1 complex respond to nucleoside analogue-induced stalled replication forks and contribute to drug resistance.
    Ewald B; Sampath D; Plunkett W
    Cancer Res; 2008 Oct; 68(19):7947-55. PubMed ID: 18829552
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks.
    Takemura H; Rao VA; Sordet O; Furuta T; Miao ZH; Meng L; Zhang H; Pommier Y
    J Biol Chem; 2006 Oct; 281(41):30814-23. PubMed ID: 16905549
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Mre11-Rad50-Nbs1 complex mediates activation of TopBP1 by ATM.
    Yoo HY; Kumagai A; Shevchenko A; Shevchenko A; Dunphy WG
    Mol Biol Cell; 2009 May; 20(9):2351-60. PubMed ID: 19279141
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex.
    Lee JH; Paull TT
    Science; 2004 Apr; 304(5667):93-6. PubMed ID: 15064416
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A role for the MRN complex in ATR activation via TOPBP1 recruitment.
    Duursma AM; Driscoll R; Elias JE; Cimprich KA
    Mol Cell; 2013 Apr; 50(1):116-22. PubMed ID: 23582259
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Suppression of DNA-damage checkpoint signaling by Rsk-mediated phosphorylation of Mre11.
    Chen C; Zhang L; Huang NJ; Huang B; Kornbluth S
    Proc Natl Acad Sci U S A; 2013 Dec; 110(51):20605-10. PubMed ID: 24297933
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ataxia-telangiectasia-like disorder (ATLD)-its clinical presentation and molecular basis.
    Taylor AM; Groom A; Byrd PJ
    DNA Repair (Amst); 2004; 3(8-9):1219-25. PubMed ID: 15279810
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular basis of ataxia telangiectasia and related diseases.
    Ball LG; Xiao W
    Acta Pharmacol Sin; 2005 Aug; 26(8):897-907. PubMed ID: 16038621
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.