BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

209 related articles for article (PubMed ID: 16625151)

  • 1. Ubiquitin-dependent degradation of SnoN and Ski is increased in renal fibrosis induced by obstructive injury.
    Fukasawa H; Yamamoto T; Togawa A; Ohashi N; Fujigaki Y; Oda T; Uchida C; Kitagawa K; Hattori T; Suzuki S; Kitagawa M; Hishida A
    Kidney Int; 2006 May; 69(10):1733-40. PubMed ID: 16625151
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Downregulation of SnoN expression in obstructive nephropathy is mediated by an enhanced ubiquitin-dependent degradation.
    Tan R; Zhang J; Tan X; Zhang X; Yang J; Liu Y
    J Am Soc Nephrol; 2006 Oct; 17(10):2781-91. PubMed ID: 16959829
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Downregulation of Smad transcriptional corepressors SnoN and Ski in the fibrotic kidney: an amplification mechanism for TGF-beta1 signaling.
    Yang J; Zhang X; Li Y; Liu Y
    J Am Soc Nephrol; 2003 Dec; 14(12):3167-77. PubMed ID: 14638915
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Down-regulation of Smad7 expression by ubiquitin-dependent degradation contributes to renal fibrosis in obstructive nephropathy in mice.
    Fukasawa H; Yamamoto T; Togawa A; Ohashi N; Fujigaki Y; Oda T; Uchida C; Kitagawa K; Hattori T; Suzuki S; Kitagawa M; Hishida A
    Proc Natl Acad Sci U S A; 2004 Jun; 101(23):8687-92. PubMed ID: 15173588
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The downregulation of SnoN expression in human renal proximal tubule epithelial cells under high-glucose conditions is mediated by an increase in Smurf2 expression through TGF-β1 signaling.
    Li X; Diao Z; Ding J; Liu R; Wang L; Huang W; Liu W
    Int J Mol Med; 2016 Feb; 37(2):415-22. PubMed ID: 26743567
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MAD2B-mediated SnoN downregulation is implicated in fibroblast activation and tubulointerstitial fibrosis.
    Tang H; Su H; Fan D; Ye C; Lei CT; Jiang HJ; Gao P; He FF; Zhang C
    Am J Physiol Renal Physiol; 2016 Jul; 311(1):F207-16. PubMed ID: 27122545
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Perspectives on blockade of TGFbeta overexpression.
    Huang Y; Border WA; Noble NA
    Kidney Int; 2006 May; 69(10):1713-4. PubMed ID: 16688190
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Vitamin E ameliorates renal fibrosis by inhibition of TGF-beta/Smad2/3 signaling pathway in UUO mice.
    Tasanarong A; Kongkham S; Duangchana S; Thitiarchakul S; Eiam-Ong S
    J Med Assoc Thai; 2011 Dec; 94 Suppl 7():S1-9. PubMed ID: 22619900
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Up-regulated transcriptional repressors SnoN and Ski bind Smad proteins to antagonize transforming growth factor-beta signals during liver regeneration.
    Macias-Silva M; Li W; Leu JI; Crissey MA; Taub R
    J Biol Chem; 2002 Aug; 277(32):28483-90. PubMed ID: 12023281
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN.
    Stroschein SL; Bonni S; Wrana JL; Luo K
    Genes Dev; 2001 Nov; 15(21):2822-36. PubMed ID: 11691834
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeted disruption of TGF-beta1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction.
    Sato M; Muragaki Y; Saika S; Roberts AB; Ooshima A
    J Clin Invest; 2003 Nov; 112(10):1486-94. PubMed ID: 14617750
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Actin-cytoskeleton polymerization differentially controls the stability of Ski and SnoN co-repressors in normal but not in transformed hepatocytes.
    Caligaris C; Vázquez-Victorio G; Sosa-Garrocho M; Ríos-López DG; Marín-Hernández A; Macías-Silva M
    Biochim Biophys Acta; 2015 Sep; 1850(9):1832-41. PubMed ID: 26002202
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The transforming activity of Ski and SnoN is dependent on their ability to repress the activity of Smad proteins.
    He J; Tegen SB; Krawitz AR; Martin GS; Luo K
    J Biol Chem; 2003 Aug; 278(33):30540-7. PubMed ID: 12764135
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Arkadia-Smad7-mediated positive regulation of TGF-beta signaling in a rat model of tubulointerstitial fibrosis.
    Liu FY; Li XZ; Peng YM; Liu H; Liu YH
    Am J Nephrol; 2007; 27(2):176-83. PubMed ID: 17347560
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Two short segments of Smad3 are important for specific interaction of Smad3 with c-Ski and SnoN.
    Mizuide M; Hara T; Furuya T; Takeda M; Kusanagi K; Inada Y; Mori M; Imamura T; Miyazawa K; Miyazono K
    J Biol Chem; 2003 Jan; 278(1):531-6. PubMed ID: 12426322
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Smad ubiquitination regulatory factor-2 in the fibrotic kidney: regulation, target specificity, and functional implication.
    Tan R; He W; Lin X; Kiss LP; Liu Y
    Am J Physiol Renal Physiol; 2008 May; 294(5):F1076-83. PubMed ID: 18353873
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Smad3 deficiency attenuates renal fibrosis, inflammation,and apoptosis after unilateral ureteral obstruction.
    Inazaki K; Kanamaru Y; Kojima Y; Sueyoshi N; Okumura K; Kaneko K; Yamashiro Y; Ogawa H; Nakao A
    Kidney Int; 2004 Aug; 66(2):597-604. PubMed ID: 15253712
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A novel mechanism by which hepatocyte growth factor blocks tubular epithelial to mesenchymal transition.
    Yang J; Dai C; Liu Y
    J Am Soc Nephrol; 2005 Jan; 16(1):68-78. PubMed ID: 15537870
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Arkadia represses the expression of myoblast differentiation markers through degradation of Ski and the Ski-bound Smad complex in C2C12 myoblasts.
    Yuzawa H; Koinuma D; Maeda S; Yamamoto K; Miyazawa K; Imamura T
    Bone; 2009 Jan; 44(1):53-60. PubMed ID: 18950738
    [TBL] [Abstract][Full Text] [Related]  

  • 20. TGF-beta induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation.
    Bonni S; Wang HR; Causing CG; Kavsak P; Stroschein SL; Luo K; Wrana JL
    Nat Cell Biol; 2001 Jun; 3(6):587-95. PubMed ID: 11389444
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.