These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

78 related articles for article (PubMed ID: 16626651)

  • 1. Loss of nicastrin elicits an apoptotic phenotype in mouse embryos.
    Nguyen V; Hawkins C; Bergeron C; Supala A; Huang J; Westaway D; St George-Hyslop P; Rozmahel R
    Brain Res; 2006 May; 1086(1):76-84. PubMed ID: 16626651
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Excess of nicastrin in brain results in heterozygosity having no effect on endogenous APP processing and amyloid peptide levels in vivo.
    Brijbassi S; Amtul Z; Newbigging S; Westaway D; St George-Hyslop P; Rozmahel RF
    Neurobiol Dis; 2007 Feb; 25(2):291-6. PubMed ID: 17071095
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Nicastrin expression in mouse peripheral tissues is not co-ordinated with presenilin and is high in muscle.
    Ilaya NT; Evin G; Masters CL; Culvenor JG
    J Neurochem; 2004 Oct; 91(1):230-7. PubMed ID: 15379903
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Rat nicastrin gene: cDNA isolation, mRNA variants and expression pattern analysis.
    Confaloni A; Crestini A; Albani D; Piscopo P; Campeggi LM; Terreni L; Tartaglia M; Forloni G
    Brain Res Mol Brain Res; 2005 May; 136(1-2):12-22. PubMed ID: 15893582
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Analysis of Notch function in presomitic mesoderm suggests a gamma-secretase-independent role for presenilins in somite differentiation.
    Huppert SS; Ilagan MX; De Strooper B; Kopan R
    Dev Cell; 2005 May; 8(5):677-88. PubMed ID: 15866159
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Increased expression of the gamma-secretase components presenilin-1 and nicastrin in activated astrocytes and microglia following traumatic brain injury.
    Nadler Y; Alexandrovich A; Grigoriadis N; Hartmann T; Rao KS; Shohami E; Stein R
    Glia; 2008 Apr; 56(5):552-67. PubMed ID: 18240300
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Conserved residues in juxtamembrane region of the extracellular domain of nicastrin are essential for gamma-secretase complex formation.
    Walker ES; Martinez M; Wang J; Goate A
    J Neurochem; 2006 Jul; 98(1):300-9. PubMed ID: 16805816
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cellular localization of Nicastrin affects amyloid beta species production.
    Morais VA; Leight S; Pijak DS; Lee VM; Costa J
    FEBS Lett; 2008 Feb; 582(3):427-33. PubMed ID: 18201567
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mice lacking Dad1, the defender against apoptotic death-1, express abnormal N-linked glycoproteins and undergo increased embryonic apoptosis.
    Hong NA; Flannery M; Hsieh SN; Cado D; Pedersen R; Winoto A
    Dev Biol; 2000 Apr; 220(1):76-84. PubMed ID: 10720432
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Deletion of Dad1 in mice induces an apoptosis-associated embryonic death.
    Brewster JL; Martin SL; Toms J; Goss D; Wang K; Zachrone K; Davis A; Carlson G; Hood L; Coffin JD
    Genesis; 2000 Apr; 26(4):271-8. PubMed ID: 10748466
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Overexpression of connexin43 alters the mutant phenotype of midgestational wnt-1 null mice resulting in recovery of the midbrain and cerebellum.
    Melloy PG; Kusnierczyk MK; Meyer RA; Lo CW; Desmond ME
    Anat Rec A Discov Mol Cell Evol Biol; 2005 Mar; 283(1):224-38. PubMed ID: 15678491
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Begacestat (GSI-953): a novel, selective thiophene sulfonamide inhibitor of amyloid precursor protein gamma-secretase for the treatment of Alzheimer's disease.
    Martone RL; Zhou H; Atchison K; Comery T; Xu JZ; Huang X; Gong X; Jin M; Kreft A; Harrison B; Mayer SC; Aschmies S; Gonzales C; Zaleska MM; Riddell DR; Wagner E; Lu P; Sun SC; Sonnenberg-Reines J; Oganesian A; Adkins K; Leach MW; Clarke DW; Huryn D; Abou-Gharbia M; Magolda R; Bard J; Frick G; Raje S; Forlow SB; Balliet C; Burczynski ME; Reinhart PH; Wan HI; Pangalos MN; Jacobsen JS
    J Pharmacol Exp Ther; 2009 Nov; 331(2):598-608. PubMed ID: 19671883
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Conditional forebrain inactivation of nicastrin causes progressive memory impairment and age-related neurodegeneration.
    Tabuchi K; Chen G; Südhof TC; Shen J
    J Neurosci; 2009 Jun; 29(22):7290-301. PubMed ID: 19494151
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The Alzheimer's disease-associated gamma-secretase complex: functional domains in the presenilin 1 protein.
    Laudon H; Winblad B; Näslund J
    Physiol Behav; 2007 Sep; 92(1-2):115-20. PubMed ID: 17588625
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Presenilin 1 is involved in the maturation of beta-site amyloid precursor protein-cleaving enzyme 1 (BACE1).
    Kuzuya A; Uemura K; Kitagawa N; Aoyagi N; Kihara T; Ninomiya H; Ishiura S; Takahashi R; Shimohama S
    J Neurosci Res; 2007 Jan; 85(1):153-65. PubMed ID: 17075903
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Increase in presenilin 1 (PS1) levels in senescence-accelerated mice (SAMP8) may indirectly impair memory by affecting amyloid precursor protein (APP) processing.
    Kumar VB; Franko M; Banks WA; Kasinadhuni P; Farr SA; Vyas K; Choudhuri V; Morley JE
    J Exp Biol; 2009 Feb; 212(Pt 4):494-8. PubMed ID: 19181896
    [TBL] [Abstract][Full Text] [Related]  

  • 17. An alternative spliced mouse presenilin-2 mRNA encodes a novel gamma-secretase inhibitor.
    Suzuki Y; Ohta K; Itoh M; Sakoh-Sumitomo Y; Mitsuda T; Ueda M; Hayakawa-Yano Y; Li S; Hida Y; Inuzuka T; Jung YK; Nakagawa T
    FEBS Lett; 2009 May; 583(9):1403-8. PubMed ID: 19376115
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The discovery and role of CD147 as a subunit of gamma-secretase complex.
    Zhou S; Zhou H; Walian PJ; Jap BK
    Drug News Perspect; 2006 Apr; 19(3):133-8. PubMed ID: 16804564
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differential role of Presenilin-1 and -2 on mitochondrial membrane potential and oxygen consumption in mouse embryonic fibroblasts.
    Behbahani H; Shabalina IG; Wiehager B; Concha H; Hultenby K; Petrovic N; Nedergaard J; Winblad B; Cowburn RF; Ankarcrona M
    J Neurosci Res; 2006 Sep; 84(4):891-902. PubMed ID: 16883555
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nanos3 maintains the germ cell lineage in the mouse by suppressing both Bax-dependent and -independent apoptotic pathways.
    Suzuki H; Tsuda M; Kiso M; Saga Y
    Dev Biol; 2008 Jun; 318(1):133-42. PubMed ID: 18436203
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.