410 related articles for article (PubMed ID: 16630632)
1. Transition-state complex of the purine-specific nucleoside hydrolase of T. vivax: enzyme conformational changes and implications for catalysis.
Versées W; Barlow J; Steyaert J
J Mol Biol; 2006 Jun; 359(2):331-46. PubMed ID: 16630632
[TBL] [Abstract][Full Text] [Related]
2. Structure and function of a novel purine specific nucleoside hydrolase from Trypanosoma vivax.
Versées W; Decanniere K; Pellé R; Depoorter J; Brosens E; Parkin DW; Steyaert J
J Mol Biol; 2001 Apr; 307(5):1363-79. PubMed ID: 11292348
[TBL] [Abstract][Full Text] [Related]
3. Computational study of IAG-nucleoside hydrolase: determination of the preferred ground state conformation and the role of active site residues.
Mazumder-Shivakumar D; Bruice TC
Biochemistry; 2005 May; 44(21):7805-17. PubMed ID: 15909995
[TBL] [Abstract][Full Text] [Related]
4. Leaving group activation by aromatic stacking: an alternative to general acid catalysis.
Versées W; Loverix S; Vandemeulebroucke A; Geerlings P; Steyaert J
J Mol Biol; 2004 Apr; 338(1):1-6. PubMed ID: 15050818
[TBL] [Abstract][Full Text] [Related]
5. N-Arylmethyl substituted iminoribitol derivatives as inhibitors of a purine specific nucleoside hydrolase.
Goeminne A; Berg M; McNaughton M; Bal G; Surpateanu G; Van der Veken P; De Prol S; Versées W; Steyaert J; Haemers A; Augustyns K
Bioorg Med Chem; 2008 Jul; 16(14):6752-63. PubMed ID: 18571422
[TBL] [Abstract][Full Text] [Related]
6. One-third-the-sites transition-state inhibitors for purine nucleoside phosphorylase.
Miles RW; Tyler PC; Furneaux RH; Bagdassarian CK; Schramm VL
Biochemistry; 1998 Jun; 37(24):8615-21. PubMed ID: 9628722
[TBL] [Abstract][Full Text] [Related]
7. Crystal structure of calf spleen purine nucleoside phosphorylase with two full trimers in the asymmetric unit: important implications for the mechanism of catalysis.
Bzowska A; Koellner G; Wielgus-Kutrowska B; Stroh A; Raszewski G; Holý A; Steiner T; Frank J
J Mol Biol; 2004 Sep; 342(3):1015-32. PubMed ID: 15342253
[TBL] [Abstract][Full Text] [Related]
8. Pre-steady-state analysis of the nucleoside hydrolase of Trypanosoma vivax. Evidence for half-of-the-sites reactivity and rate-limiting product release.
Vandemeulebroucke A; Versées W; De Vos S; Van Holsbeke E; Steyaert J
Biochemistry; 2003 Nov; 42(44):12902-8. PubMed ID: 14596604
[TBL] [Abstract][Full Text] [Related]
9. Enzyme-substrate interactions in the purine-specific nucleoside hydrolase from Trypanosoma vivax.
Versées W; Decanniere K; Van Holsbeke E; Devroede N; Steyaert J
J Biol Chem; 2002 May; 277(18):15938-46. PubMed ID: 11854281
[TBL] [Abstract][Full Text] [Related]
10. Crystal structures of T. vivax nucleoside hydrolase in complex with new potent and specific inhibitors.
Versées W; Goeminne A; Berg M; Vandemeulebroucke A; Haemers A; Augustyns K; Steyaert J
Biochim Biophys Acta; 2009 Jun; 1794(6):953-60. PubMed ID: 19281874
[TBL] [Abstract][Full Text] [Related]
11. Open and closed conformation of the E. coli purine nucleoside phosphorylase active center and implications for the catalytic mechanism.
Koellner G; Bzowska A; Wielgus-Kutrowska B; Luić M; Steiner T; Saenger W; Stepiński J
J Mol Biol; 2002 Jan; 315(3):351-71. PubMed ID: 11786017
[TBL] [Abstract][Full Text] [Related]
12. QM/MM molecular dynamics study of purine-specific nucleoside hydrolase.
Wu R; Gong W; Liu T; Zhang Y; Cao Z
J Phys Chem B; 2012 Feb; 116(6):1984-91. PubMed ID: 22257300
[TBL] [Abstract][Full Text] [Related]
13. Three-dimensional structure of the inosine-uridine nucleoside N-ribohydrolase from Crithidia fasciculata.
Degano M; Gopaul DN; Scapin G; Schramm VL; Sacchettini JC
Biochemistry; 1996 May; 35(19):5971-81. PubMed ID: 8634238
[TBL] [Abstract][Full Text] [Related]
14. Transition state structure of purine nucleoside phosphorylase and principles of atomic motion in enzymatic catalysis.
Fedorov A; Shi W; Kicska G; Fedorov E; Tyler PC; Furneaux RH; Hanson JC; Gainsford GJ; Larese JZ; Schramm VL; Almo SC
Biochemistry; 2001 Jan; 40(4):853-60. PubMed ID: 11170405
[TBL] [Abstract][Full Text] [Related]
15. Assignment of downfield proton resonances in purine nucleoside phosphorylase immucillin-H complex by saturation-transferred NOEs.
Deng H; Lewandowicz A; Cahill SM; Furneaux RH; Tyler PC; Girvin ME; Callender RH; Schramm VL
Biochemistry; 2004 Feb; 43(7):1980-7. PubMed ID: 14967038
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and biochemical evaluation of guanidino-alkyl-ribitol derivatives as nucleoside hydrolase inhibitors.
Goeminne A; McNaughton M; Bal G; Surpateanu G; Van Der Veken P; De Prol S; Versées W; Steyaert J; Haemers A; Augustyns K
Eur J Med Chem; 2008 Feb; 43(2):315-26. PubMed ID: 17582660
[TBL] [Abstract][Full Text] [Related]
17. Over-the-barrier transition state analogues and crystal structure with Mycobacterium tuberculosis purine nucleoside phosphorylase.
Lewandowicz A; Shi W; Evans GB; Tyler PC; Furneaux RH; Basso LA; Santos DS; Almo SC; Schramm VL
Biochemistry; 2003 May; 42(20):6057-66. PubMed ID: 12755607
[TBL] [Abstract][Full Text] [Related]
18. A flexible loop as a functional element in the catalytic mechanism of nucleoside hydrolase from Trypanosoma vivax.
Vandemeulebroucke A; De Vos S; Van Holsbeke E; Steyaert J; Versées W
J Biol Chem; 2008 Aug; 283(32):22272-82. PubMed ID: 18519562
[TBL] [Abstract][Full Text] [Related]
19. Isozyme-specific transition state inhibitors for the trypanosomal nucleoside hydrolases.
Parkin DW; Limberg G; Tyler PC; Furneaux RH; Chen XY; Schramm VL
Biochemistry; 1997 Mar; 36(12):3528-34. PubMed ID: 9132003
[TBL] [Abstract][Full Text] [Related]
20. Multiple transients in the pre-steady-state of nucleoside hydrolase reveal complex substrate binding, product base release, and two apparent rates of chemistry.
Vandemeulebroucke A; Versées W; Steyaert J; Barlow JN
Biochemistry; 2006 Aug; 45(30):9307-18. PubMed ID: 16866377
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
