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2. Mediterranean dietary traditions for the molecular treatment of human cancer: anti-oncogenic actions of the main olive oil's monounsaturated fatty acid oleic acid (18:1n-9). Menendez JA; Lupu R Curr Pharm Biotechnol; 2006 Dec; 7(6):495-502. PubMed ID: 17168666 [TBL] [Abstract][Full Text] [Related]
3. A genomic explanation connecting "Mediterranean diet", olive oil and cancer: oleic acid, the main monounsaturated fatty acid of olive oil, induces formation of inhibitory "PEA3 transcription factor-PEA3 DNA binding site" complexes at the Her-2/neu (erbB-2) oncogene promoter in breast, ovarian and stomach cancer cells. Menendez JA; Papadimitropoulou A; Vellon L; Lupu R Eur J Cancer; 2006 Oct; 42(15):2425-32. PubMed ID: 16406575 [TBL] [Abstract][Full Text] [Related]
4. Oleic acid, the main monounsaturated fatty acid of olive oil, suppresses Her-2/neu (erbB-2) expression and synergistically enhances the growth inhibitory effects of trastuzumab (Herceptin) in breast cancer cells with Her-2/neu oncogene amplification. Menendez JA; Vellon L; Colomer R; Lupu R Ann Oncol; 2005 Mar; 16(3):359-71. PubMed ID: 15642702 [TBL] [Abstract][Full Text] [Related]
5. HER2 (erbB-2)-targeted effects of the omega-3 polyunsaturated fatty acid, alpha-linolenic acid (ALA; 18:3n-3), in breast cancer cells: the "fat features" of the "Mediterranean diet" as an "anti-HER2 cocktail". Menéndez JA; Vázquez-Martín A; Ropero S; Colomer R; Lupu R Clin Transl Oncol; 2006 Nov; 8(11):812-20. PubMed ID: 17134970 [TBL] [Abstract][Full Text] [Related]
6. Antitumoral actions of the anti-obesity drug orlistat (XenicalTM) in breast cancer cells: blockade of cell cycle progression, promotion of apoptotic cell death and PEA3-mediated transcriptional repression of Her2/neu (erbB-2) oncogene. Menendez JA; Vellon L; Lupu R Ann Oncol; 2005 Aug; 16(8):1253-67. PubMed ID: 15870086 [TBL] [Abstract][Full Text] [Related]
7. Olive oil's bitter principle reverses acquired autoresistance to trastuzumab (Herceptin) in HER2-overexpressing breast cancer cells. Menendez JA; Vazquez-Martin A; Colomer R; Brunet J; Carrasco-Pancorbo A; Garcia-Villalba R; Fernandez-Gutierrez A; Segura-Carretero A BMC Cancer; 2007 May; 7():80. PubMed ID: 17490486 [TBL] [Abstract][Full Text] [Related]
8. Oleic acid suppresses overexpression of ERBB2 oncogene. Nelson R Lancet Oncol; 2005 Feb; 6(2):69. PubMed ID: 15704291 [No Abstract] [Full Text] [Related]
9. Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells. Menendez JA; Vellon L; Mehmi I; Oza BP; Ropero S; Colomer R; Lupu R Proc Natl Acad Sci U S A; 2004 Jul; 101(29):10715-20. PubMed ID: 15235125 [TBL] [Abstract][Full Text] [Related]
13. Modulatory effects and molecular mechanisms of olive oil and other dietary lipids in breast cancer. Escrich E; Solanas M; Moral R; Escrich R Curr Pharm Des; 2011; 17(8):813-30. PubMed ID: 21443482 [TBL] [Abstract][Full Text] [Related]
14. Targeting fatty acid synthase-driven lipid rafts: a novel strategy to overcome trastuzumab resistance in breast cancer cells. Menendez JA; Vellon L; Lupu R Med Hypotheses; 2005; 64(5):997-1001. PubMed ID: 15780499 [TBL] [Abstract][Full Text] [Related]
15. Pharmacological blockade of fatty acid synthase (FASN) reverses acquired autoresistance to trastuzumab (Herceptin by transcriptionally inhibiting 'HER2 super-expression' occurring in high-dose trastuzumab-conditioned SKBR3/Tzb100 breast cancer cells. Vazquez-Martin A; Colomer R; Brunet J; Menendez JA Int J Oncol; 2007 Oct; 31(4):769-76. PubMed ID: 17786307 [TBL] [Abstract][Full Text] [Related]
16. DNA topoisomerase IIalpha (TOP2A) inhibitors up-regulate fatty acid synthase gene expression in SK-Br3 breast cancer cells: in vitro evidence for a 'functional amplicon' involving FAS, Her-2/neu and TOP2A genes. Menendez JA; Vellon L; Lupu R Int J Mol Med; 2006 Dec; 18(6):1081-7. PubMed ID: 17089011 [TBL] [Abstract][Full Text] [Related]
17. Effect of gamma-linolenic acid on the transcriptional activity of the Her-2/neu (erbB-2) oncogene. Menendez JA; Vellon L; Colomer R; Lupu R J Natl Cancer Inst; 2005 Nov; 97(21):1611-5. PubMed ID: 16264182 [TBL] [Abstract][Full Text] [Related]
18. Lipid-conjugated telomerase template antagonists sensitize resistant HER2-positive breast cancer cells to trastuzumab. Goldblatt EM; Erickson PA; Gentry ER; Gryaznov SM; Herbert BS Breast Cancer Res Treat; 2009 Nov; 118(1):21-32. PubMed ID: 18853252 [TBL] [Abstract][Full Text] [Related]
19. Palmitate-induced ER stress increases trastuzumab sensitivity in HER2/neu-positive breast cancer cells. Baumann J; Wong J; Sun Y; Conklin DS BMC Cancer; 2016 Jul; 16():551. PubMed ID: 27464732 [TBL] [Abstract][Full Text] [Related]
20. Targeting endothelin A receptor enhances anti-proliferative and anti-invasive effects of the HER2 antibody trastuzumab in HER2-overexpressing breast cancer cells. Fischgräbe J; Götte M; Michels K; Kiesel L; Wülfing P Int J Cancer; 2010 Aug; 127(3):696-706. PubMed ID: 19960438 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]