BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

236 related articles for article (PubMed ID: 16638752)

  • 1. Crystal structure of the herpes simplex virus 1 DNA polymerase.
    Liu S; Knafels JD; Chang JS; Waszak GA; Baldwin ET; Deibel MR; Thomsen DR; Homa FL; Wells PA; Tory MC; Poorman RA; Gao H; Qiu X; Seddon AP
    J Biol Chem; 2006 Jun; 281(26):18193-200. PubMed ID: 16638752
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Amino acid changes within conserved region III of the herpes simplex virus and human cytomegalovirus DNA polymerases confer resistance to 4-oxo-dihydroquinolines, a novel class of herpesvirus antiviral agents.
    Thomsen DR; Oien NL; Hopkins TA; Knechtel ML; Brideau RJ; Wathen MW; Homa FL
    J Virol; 2003 Feb; 77(3):1868-76. PubMed ID: 12525621
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effects of Acyclovir, Foscarnet, and Ribonucleotides on Herpes Simplex Virus-1 DNA Polymerase: Mechanistic Insights and a Novel Mechanism for Preventing Stable Incorporation of Ribonucleotides into DNA.
    Vashishtha AK; Kuchta RD
    Biochemistry; 2016 Feb; 55(7):1168-77. PubMed ID: 26836009
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 4-Oxo-4,7-dihydrothieno[2,3-b]pyridines as non-nucleoside inhibitors of human cytomegalovirus and related herpesvirus polymerases.
    Schnute ME; Cudahy MM; Brideau RJ; Homa FL; Hopkins TA; Knechtel ML; Oien NL; Pitts TW; Poorman RA; Wathen MW; Wieber JL
    J Med Chem; 2005 Sep; 48(18):5794-804. PubMed ID: 16134946
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Contrasting effects of W781V and W780V mutations in helix N of herpes simplex virus 1 and human cytomegalovirus DNA polymerases on antiviral drug susceptibility.
    Piret J; Goyette N; Eckenroth BE; Drouot E; Götte M; Boivin G
    J Virol; 2015 Apr; 89(8):4636-44. PubMed ID: 25673718
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Non-nucleosidic inhibition of Herpes simplex virus DNA polymerase: mechanistic insights into the anti-herpetic mode of action of herbal drug withaferin A.
    Grover A; Agrawal V; Shandilya A; Bisaria VS; Sundar D
    BMC Bioinformatics; 2011; 12 Suppl 13(Suppl 13):S22. PubMed ID: 22373101
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Anti-Human Immunodeficiency Virus Drug Tenofovir, a Reverse Transcriptase Inhibitor, Also Targets the Herpes Simplex Virus DNA Polymerase.
    Andrei G; Gillemot S; Topalis D; Snoeck R
    J Infect Dis; 2018 Feb; 217(5):790-801. PubMed ID: 29186456
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DNA polymerase mutations in drug-resistant herpes simplex virus mutants determine in vivo neurovirulence and drug-enzyme interactions.
    Andrei G; Fiten P; Froeyen M; De Clercq E; Opdenakker G; Snoeck R
    Antivir Ther; 2007; 12(5):719-32. PubMed ID: 17713155
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synergistic antiviral activity of acyclovir and vidarabine against herpes simplex virus types 1 and 2 and varicella-zoster virus.
    Suzuki M; Okuda T; Shiraki K
    Antiviral Res; 2006 Nov; 72(2):157-61. PubMed ID: 16797734
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of herpesvirus replication by a series of 4-oxo-dihydroquinolines with viral polymerase activity.
    Hartline CB; Harden EA; Williams-Aziz SL; Kushner NL; Brideau RJ; Kern ER
    Antiviral Res; 2005 Feb; 65(2):97-105. PubMed ID: 15708636
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Distribution and effects of amino acid changes in drug-resistant α and β herpesviruses DNA polymerase.
    Topalis D; Gillemot S; Snoeck R; Andrei G
    Nucleic Acids Res; 2016 Nov; 44(20):9530-9554. PubMed ID: 27694307
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The pre-NH(2)-terminal domain of the herpes simplex virus 1 DNA polymerase catalytic subunit is required for efficient viral replication.
    Terrell SL; Coen DM
    J Virol; 2012 Oct; 86(20):11057-65. PubMed ID: 22875965
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural understanding of non-nucleoside inhibition in an elongating herpesvirus polymerase.
    Hayes RP; Heo MR; Mason M; Reid J; Burlein C; Armacost KA; Tellers DM; Raheem I; Shaw AW; Murray E; McKenna PM; Abeywickrema P; Sharma S; Soisson SM; Klein D
    Nat Commun; 2021 May; 12(1):3040. PubMed ID: 34031403
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Single nucleotide polymorphisms of thymidine kinase and DNA polymerase genes in clinical herpes simplex virus type 1 isolates associated with different resistance phenotypes.
    Schubert A; Gentner E; Bohn K; Schwarz M; Mertens T; Sauerbrei A
    Antiviral Res; 2014 Jul; 107():16-22. PubMed ID: 24747042
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Finger domain mutation affects enzyme activity, DNA replication efficiency, and fidelity of an exonuclease-deficient DNA polymerase of herpes simplex virus type 1.
    Tian W; Hwang YT; Lu Q; Hwang CB
    J Virol; 2009 Jul; 83(14):7194-201. PubMed ID: 19420083
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Utility of ultra-deep sequencing for detection of varicella-zoster virus antiviral resistance mutations.
    Mercier-Darty M; Boutolleau D; Lepeule R; Rodriguez C; Burrel S
    Antiviral Res; 2018 Mar; 151():20-23. PubMed ID: 29337163
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Drug resistance patterns of recombinant herpes simplex virus DNA polymerase mutants generated with a set of overlapping cosmids and plasmids.
    Bestman-Smith J; Boivin G
    J Virol; 2003 Jul; 77(14):7820-9. PubMed ID: 12829822
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ASP2151, a novel helicase-primase inhibitor, possesses antiviral activity against varicella-zoster virus and herpes simplex virus types 1 and 2.
    Chono K; Katsumata K; Kontani T; Kobayashi M; Sudo K; Yokota T; Konno K; Shimizu Y; Suzuki H
    J Antimicrob Chemother; 2010 Aug; 65(8):1733-41. PubMed ID: 20534624
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The structure and function of the HSV DNA replication proteins: defining novel antiviral targets.
    Matthews JT; Terry BJ; Field AK
    Antiviral Res; 1993 Feb; 20(2):89-114. PubMed ID: 8384825
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phenotypic and genotypic characterization of acyclovir-resistant corneal HSV-1 isolates from immunocompetent patients with recurrent herpetic keratitis.
    Burrel S; Boutolleau D; Azar G; Doan S; Deback C; Cochereau I; Agut H; Gabison EE
    J Clin Virol; 2013 Sep; 58(1):321-4. PubMed ID: 23731845
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.