293 related articles for article (PubMed ID: 16640327)
1. Identification of type 1 inosine monophosphate dehydrogenase as an antiangiogenic drug target.
Chong CR; Qian DZ; Pan F; Wei Y; Pili R; Sullivan DJ; Liu JO
J Med Chem; 2006 May; 49(9):2677-80. PubMed ID: 16640327
[TBL] [Abstract][Full Text] [Related]
2. Structure-activity relationships for inhibition of inosine monophosphate dehydrogenase and differentiation induction of K562 cells among the mycophenolic acid derivatives.
Mitsuhashi S; Takenaka J; Iwamori K; Nakajima N; Ubukata M
Bioorg Med Chem; 2010 Nov; 18(22):8106-11. PubMed ID: 20934342
[TBL] [Abstract][Full Text] [Related]
3. Mycophenolic acid analogs with a modified metabolic profile.
Chen L; Wilson DJ; Labello NP; Jayaram HN; Pankiewicz KW
Bioorg Med Chem; 2008 Oct; 16(20):9340-5. PubMed ID: 18809333
[TBL] [Abstract][Full Text] [Related]
4. Two new members of mycophenolic acid family from Penicillium brevicompactum Dierckx.
Lu X; Zheng Z; Zhang H; Huo C; Dong Y; Ma Y; Ren X; Ke A; He J; Gu Y; Shi Q
J Antibiot (Tokyo); 2009 Sep; 62(9):527-9. PubMed ID: 19575040
[No Abstract] [Full Text] [Related]
5. IMP dehydrogenase basal activity in MOLT-4 human leukaemia cells is altered by mycophenolic acid and 6-thioguanosine.
Vethe NT; Bremer S; Bergan S
Scand J Clin Lab Invest; 2008; 68(4):277-85. PubMed ID: 18609073
[TBL] [Abstract][Full Text] [Related]
6. Cofactor-type inhibitors of inosine monophosphate dehydrogenase via modular approach: targeting the pyrophosphate binding sub-domain.
Felczak K; Chen L; Wilson D; Williams J; Vince R; Petrelli R; Jayaram HN; Kusumanchi P; Kumar M; Pankiewicz KW
Bioorg Med Chem; 2011 Mar; 19(5):1594-605. PubMed ID: 21324702
[TBL] [Abstract][Full Text] [Related]
7. Inosine 5'-monophosphate dehydrogenase inhibition by mycophenolic acid impairs maturation and function of dendritic cells.
Dubsky PC; Friedl J; Stift A; Bachleitner-Hofmann T; Jakesz R; Gnant MF; Weigel G
Clin Chim Acta; 2006 Feb; 364(1-2):139-47. PubMed ID: 16051207
[TBL] [Abstract][Full Text] [Related]
8. Determination of inosine monophosphate dehydrogenase activity in human CD4+ cells isolated from whole blood during mycophenolic acid therapy.
Vethe NT; Bergan S
Ther Drug Monit; 2006 Oct; 28(5):608-13. PubMed ID: 17038874
[TBL] [Abstract][Full Text] [Related]
9. Phosphonic acid-containing analogues of mycophenolic acid as inhibitors of IMPDH.
Watkins WJ; Chen JM; Cho A; Chong L; Collins N; Fardis M; Huang W; Hung M; Kirschberg T; Lee WA; Liu X; Thomas W; Xu J; Zeynalzadegan A; Zhang J
Bioorg Med Chem Lett; 2006 Jul; 16(13):3479-83. PubMed ID: 16621550
[TBL] [Abstract][Full Text] [Related]
10. Mycophenolic acid displays IMPDH-dependent and IMPDH-independent effects on renal fibroblast proliferation and function.
Petrova DT; Brandhorst G; Brehmer F; Gross O; Oellerich M; Armstrong VW
Ther Drug Monit; 2010 Aug; 32(4):405-12. PubMed ID: 20592645
[TBL] [Abstract][Full Text] [Related]
11. Effects of mycophenolic acid on inosine monophosphate dehydrogenase I and II mRNA expression in white blood cells and various tissues in sheep.
Dzidic A; Prgomet C; Mohr A; Meyer K; Bauer J; Meyer HH; Pfaffl MW
J Vet Med A Physiol Pathol Clin Med; 2006 May; 53(4):163-9. PubMed ID: 16629948
[TBL] [Abstract][Full Text] [Related]
12. Dual inhibitors of inosine monophosphate dehydrogenase and histone deacetylases for cancer treatment.
Chen L; Wilson D; Jayaram HN; Pankiewicz KW
J Med Chem; 2007 Dec; 50(26):6685-91. PubMed ID: 18038969
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of IMPDH by mycophenolic acid: dissection of forward and reverse pathways using capillary electrophoresis.
Fleming MA; Chambers SP; Connelly PR; Nimmesgern E; Fox T; Bruzzese FJ; Hoe ST; Fulghum JR; Livingston DJ; Stuver CM; Sintchak MD; Wilson KP; Thomson JA
Biochemistry; 1996 Jun; 35(22):6990-7. PubMed ID: 8679523
[TBL] [Abstract][Full Text] [Related]
14. Computational insights into the inhibition of inosine 5'-monophosphate dehydrogenase by mycophenolic acid analogs: three-dimensional quantitative structure-activity relationship and molecular docking studies.
Yang N; Wang J; Wang ZW; Wang QH; Yang HG; Wang XJ; Cheng MS
Chem Biol Drug Des; 2012 Jun; 79(6):1063-71. PubMed ID: 22405057
[TBL] [Abstract][Full Text] [Related]
15. Design, synthesis and biological evaluation of novel inosine 5'-monophosphate dehydrogenase (IMPDH) inhibitors.
Dunkern T; Chavan S; Bankar D; Patil A; Kulkarni P; Kharkar PS; Prabhu A; Goebel H; Rolser E; Burckhard-Boer W; Arumugam P; Makhija MT
J Enzyme Inhib Med Chem; 2014 Jun; 29(3):408-19. PubMed ID: 23663081
[TBL] [Abstract][Full Text] [Related]
16. Nuclear magnetic resonance and molecular modeling study on mycophenolic acid: implications for binding to inosine monophosphate dehydrogenase.
Makara GM; Keserû GM; Kajtár-Peredy M; Anderson WK
J Med Chem; 1996 Mar; 39(6):1236-42. PubMed ID: 8632430
[TBL] [Abstract][Full Text] [Related]
17. Cloning, characterization and validation of inosine 5'-monophosphate dehydrogenase of Babesia gibsoni as molecular drug target.
Cao S; Aboge GO; Terkawi MA; Zhou M; Luo Y; Yu L; Li Y; Goo Y; Kamyingkird K; Masatani T; Suzuki H; Igarashi I; Nishikawa Y; Xuan X
Parasitol Int; 2013 Apr; 62(2):87-94. PubMed ID: 23142571
[TBL] [Abstract][Full Text] [Related]
18. Novel indole inhibitors of IMPDH from fragments: synthesis and initial structure-activity relationships.
Beevers RE; Buckley GM; Davies N; Fraser JL; Galvin FC; Hannah DR; Haughan AF; Jenkins K; Mack SR; Pitt WR; Ratcliffe AJ; Richard MD; Sabin V; Sharpe A; Williams SC
Bioorg Med Chem Lett; 2006 May; 16(9):2539-42. PubMed ID: 16483773
[TBL] [Abstract][Full Text] [Related]
19. Differentiation of human prostate cancer PC-3 cells induced by inhibitors of inosine 5'-monophosphate dehydrogenase.
Floryk D; Tollaksen SL; Giometti CS; Huberman E
Cancer Res; 2004 Dec; 64(24):9049-56. PubMed ID: 15604271
[TBL] [Abstract][Full Text] [Related]
20. Regulation of IL2 and NUCB1 in mononuclear cells treated with acyl glucuronide of mycophenolic acid reveals effects independent of inosine monophosphate dehydrogenase inhibition.
Petrova DT; Heller T; Hitt R; Wieland E; Oellerich M; Armstrong VW; Shipkova M
Ther Drug Monit; 2009 Feb; 31(1):31-41. PubMed ID: 19065122
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
