350 related articles for article (PubMed ID: 16644213)
1. Lysine sulfonamides as novel HIV-protease inhibitors: Nepsilon-acyl aromatic alpha-amino acids.
Stranix BR; Lavallée JF; Sévigny G; Yelle J; Perron V; LeBerre N; Herbart D; Wu JJ
Bioorg Med Chem Lett; 2006 Jul; 16(13):3459-62. PubMed ID: 16644213
[TBL] [Abstract][Full Text] [Related]
2. Lysine sulfonamides as novel HIV-protease inhibitors: Nepsilon-disubstituted ureas.
Stranix BR; Sauvé G; Bouzide A; Coté A; Sévigny G; Yelle J; Perron V
Bioorg Med Chem Lett; 2004 Aug; 14(15):3971-4. PubMed ID: 15225709
[TBL] [Abstract][Full Text] [Related]
3. Novel arylsulfonamides possessing sub-picomolar HIV protease activities and potent anti-HIV activity against wild-type and drug-resistant viral strains.
Miller JF; Furfine ES; Hanlon MH; Hazen RJ; Ray JA; Robinson L; Samano V; Spaltenstein A
Bioorg Med Chem Lett; 2004 Feb; 14(4):959-63. PubMed ID: 15013001
[TBL] [Abstract][Full Text] [Related]
4. Synthesis, antiviral activity, and pharmacokinetic evaluation of P3 pyridylmethyl analogs of oximinoarylsulfonyl HIV-1 protease inhibitors.
Randolph JT; Huang PP; Flosi WJ; DeGoey D; Klein LL; Yeung CM; Flentge C; Sun M; Zhao C; Dekhtyar T; Mo H; Colletti L; Kati W; Marsh KC; Molla A; Kempf DJ
Bioorg Med Chem; 2006 Jun; 14(12):4035-46. PubMed ID: 16504523
[TBL] [Abstract][Full Text] [Related]
5. Structure-based design: synthesis and biological evaluation of a series of novel cycloamide-derived HIV-1 protease inhibitors.
Ghosh AK; Swanson LM; Cho H; Leshchenko S; Hussain KA; Kay S; Walters DE; Koh Y; Mitsuya H
J Med Chem; 2005 May; 48(10):3576-85. PubMed ID: 15887965
[TBL] [Abstract][Full Text] [Related]
6. Lysine sulfonamides as novel HIV-protease inhibitors: optimization of the Nepsilon-acyl-phenyl spacer.
Stranix BR; Sauvé G; Bouzide A; Coté A; Sévigny G; Yelle J
Bioorg Med Chem Lett; 2003 Dec; 13(24):4289-92. PubMed ID: 14643311
[TBL] [Abstract][Full Text] [Related]
7. Structure-based design of novel HIV protease inhibitors: sulfonamide-containing 4-hydroxycoumarins and 4-hydroxy-2-pyrones as potent non-peptidic inhibitors.
Thaisrivongs S; Janakiraman MN; Chong KT; Tomich PK; Dolak LA; Turner SR; Strohbach JW; Lynn JC; Horng MM; Hinshaw RR; Watenpaugh KD
J Med Chem; 1996 Jun; 39(12):2400-10. PubMed ID: 8691434
[TBL] [Abstract][Full Text] [Related]
8. Oximinoarylsulfonamides as potent HIV protease inhibitors.
Yeung CM; Klein LL; Flentge CA; Randolph JT; Zhao C; Sun M; Dekhtyar T; Stoll VS; Kempf DJ
Bioorg Med Chem Lett; 2005 May; 15(9):2275-8. PubMed ID: 15837308
[TBL] [Abstract][Full Text] [Related]
9. Novel P1 chain-extended HIV protease inhibitors possessing potent anti-HIV activity and remarkable inverse antiviral resistance profiles.
Miller JF; Brieger M; Furfine ES; Hazen RJ; Kaldor I; Reynolds D; Sherrill RG; Spaltenstein A
Bioorg Med Chem Lett; 2005 Aug; 15(15):3496-500. PubMed ID: 15990305
[TBL] [Abstract][Full Text] [Related]
10. Reduction of peptide character of HIV protease inhibitors that exhibit nanomolar potency against multidrug resistant HIV-1 strains.
Tamamura H; Koh Y; Ueda S; Sasaki Y; Yamasaki T; Aoki M; Maeda K; Watai Y; Arikuni H; Otaka A; Mitsuya H; Fujii N
J Med Chem; 2003 Apr; 46(9):1764-8. PubMed ID: 12699395
[TBL] [Abstract][Full Text] [Related]
11. Discovery of HIV-1 protease inhibitors with picomolar affinities incorporating N-aryl-oxazolidinone-5-carboxamides as novel P2 ligands.
Ali A; Reddy GS; Cao H; Anjum SG; Nalam MN; Schiffer CA; Rana TM
J Med Chem; 2006 Dec; 49(25):7342-56. PubMed ID: 17149864
[TBL] [Abstract][Full Text] [Related]
12. Novel inhibitors of HIV protease: design, synthesis and biological evaluation of picomolar inhibitors containing cyclic P1/P2 scaffolds.
Spaltenstein A; Almond MR; Bock WJ; Cleary DG; Furfine ES; Hazen RJ; Kazmierski WM; Salituro FG; Tung RD; Wright LL
Bioorg Med Chem Lett; 2000 Jun; 10(11):1159-62. PubMed ID: 10866371
[TBL] [Abstract][Full Text] [Related]
13. Design, synthesis and biological evaluation of novel HIV-1 protease inhibitors with pentacyclic triterpenoids as P2-ligands.
Zhu M; Du XN; Li YG; Zhang GN; Wang JX; Wang YC
Bioorg Med Chem Lett; 2019 Feb; 29(3):357-361. PubMed ID: 30580917
[TBL] [Abstract][Full Text] [Related]
14. Lysine derivatives as potent HIV protease inhibitors. Discovery, synthesis and structure-activity relationship studies.
Bouzide A; Sauvé G; Yelle J
Bioorg Med Chem Lett; 2005 Mar; 15(5):1509-13. PubMed ID: 15713418
[TBL] [Abstract][Full Text] [Related]
15. Ultra-potent P1 modified arylsulfonamide HIV protease inhibitors: the discovery of GW0385.
Miller JF; Andrews CW; Brieger M; Furfine ES; Hale MR; Hanlon MH; Hazen RJ; Kaldor I; McLean EW; Reynolds D; Sammond DM; Spaltenstein A; Tung R; Turner EM; Xu RX; Sherrill RG
Bioorg Med Chem Lett; 2006 Apr; 16(7):1788-94. PubMed ID: 16458505
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and antiviral activity of P1' arylsulfonamide azacyclic urea HIV protease inhibitors.
Huang PP; Randolph JT; Klein LL; Vasavanonda S; Dekhtyar T; Stoll VS; Kempf DJ
Bioorg Med Chem Lett; 2004 Aug; 14(15):4075-8. PubMed ID: 15225729
[TBL] [Abstract][Full Text] [Related]
17. Combination of non-natural D-amino acid derivatives and allophenylnorstatine-dimethylthioproline scaffold in HIV protease inhibitors have high efficacy in mutant HIV.
Nakatani S; Hidaka K; Ami E; Nakahara K; Sato A; Nguyen JT; Hamada Y; Hori Y; Ohnishi N; Nagai A; Kimura T; Hayashi Y; Kiso Y
J Med Chem; 2008 May; 51(10):2992-3004. PubMed ID: 18426195
[TBL] [Abstract][Full Text] [Related]
18. Cyclic HIV-1 protease inhibitors derived from mannitol: synthesis, inhibitory potencies, and computational predictions of binding affinities.
Hultén J; Bonham NM; Nillroth U; Hansson T; Zuccarello G; Bouzide A; Aqvist J; Classon B; Danielson UH; Karlén A; Kvarnström I; Samuelsson B; Hallberg A
J Med Chem; 1997 Mar; 40(6):885-97. PubMed ID: 9083477
[TBL] [Abstract][Full Text] [Related]
19. Structure-activity relationships of novel HIV-1 protease inhibitors containing the 3-amino-2-chlorobenzoyl-allophenylnorstatine structure.
Mimoto T; Nojima S; Terashima K; Takaku H; Shintani M; Hayashi H
Bioorg Med Chem; 2008 Feb; 16(3):1299-308. PubMed ID: 17981045
[TBL] [Abstract][Full Text] [Related]
20. Design, asymmetric synthesis, and evaluation of pseudosymmetric sulfoximine inhibitors against HIV-1 protease.
Lu D; Sham YY; Vince R
Bioorg Med Chem; 2010 Mar; 18(5):2037-48. PubMed ID: 20138769
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
