206 related articles for article (PubMed ID: 16644220)
1. Thiazolo[5,4-f]quinazolin-9-ones, inhibitors of glycogen synthase kinase-3.
Testard A; Logé C; Léger B; Robert JM; Lozach O; Blairvacq M; Meijer L; Thiéry V; Besson T
Bioorg Med Chem Lett; 2006 Jul; 16(13):3419-23. PubMed ID: 16644220
[TBL] [Abstract][Full Text] [Related]
2. Novel 9-oxo-thiazolo[5,4-f]quinazoline-2-carbonitrile derivatives as dual cyclin-dependent kinase 1 (CDK1)/glycogen synthase kinase-3 (GSK-3) inhibitors: synthesis, biological evaluation and molecular modeling studies.
Logé C; Testard A; Thiéry V; Lozach O; Blairvacq M; Robert JM; Meijer L; Besson T
Eur J Med Chem; 2008 Jul; 43(7):1469-77. PubMed ID: 17981370
[TBL] [Abstract][Full Text] [Related]
3. Structural basis for the synthesis of indirubins as potent and selective inhibitors of glycogen synthase kinase-3 and cyclin-dependent kinases.
Polychronopoulos P; Magiatis P; Skaltsounis AL; Myrianthopoulos V; Mikros E; Tarricone A; Musacchio A; Roe SM; Pearl L; Leost M; Greengard P; Meijer L
J Med Chem; 2004 Feb; 47(4):935-46. PubMed ID: 14761195
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and evaluation of the antiproliferative activity of novel thiazoloquinazolinone kinases inhibitors.
Testard A; Picot L; Lozach O; Blairvacq M; Meijer L; Murillo L; Piot JM; Thiéry V; Besson T
J Enzyme Inhib Med Chem; 2005 Dec; 20(6):557-68. PubMed ID: 16408791
[TBL] [Abstract][Full Text] [Related]
5. Structure-guided discovery of cyclin-dependent kinase inhibitors.
Fischmann TO; Hruza A; Duca JS; Ramanathan L; Mayhood T; Windsor WT; Le HV; Guzi TJ; Dwyer MP; Paruch K; Doll RJ; Lees E; Parry D; Seghezzi W; Madison V
Biopolymers; 2008 May; 89(5):372-9. PubMed ID: 17937404
[TBL] [Abstract][Full Text] [Related]
6. Synthesis of novel 5-substituted indirubins as protein kinases inhibitors.
Beauchard A; Ferandin Y; Frère S; Lozach O; Blairvacq M; Meijer L; Thiéry V; Besson T
Bioorg Med Chem; 2006 Sep; 14(18):6434-43. PubMed ID: 16759872
[TBL] [Abstract][Full Text] [Related]
7. CH...O and CH...N hydrogen bonds in ligand design: a novel quinazolin-4-ylthiazol-2-ylamine protein kinase inhibitor.
Pierce AC; ter Haar E; Binch HM; Kay DP; Patel SR; Li P
J Med Chem; 2005 Feb; 48(4):1278-81. PubMed ID: 15715498
[TBL] [Abstract][Full Text] [Related]
8. Investigation of potential glycogen synthase kinase 3 inhibitors using pharmacophore mapping and virtual screening.
Dessalew N; Bharatam PV
Chem Biol Drug Des; 2006 Sep; 68(3):154-65. PubMed ID: 17062013
[TBL] [Abstract][Full Text] [Related]
9. 4-Acylamino-6-arylfuro[2,3-d]pyrimidines: potent and selective glycogen synthase kinase-3 inhibitors.
Maeda Y; Nakano M; Sato H; Miyazaki Y; Schweiker SL; Smith JL; Truesdale AT
Bioorg Med Chem Lett; 2004 Aug; 14(15):3907-11. PubMed ID: 15225695
[TBL] [Abstract][Full Text] [Related]
10. Aloisines, a new family of CDK/GSK-3 inhibitors. SAR study, crystal structure in complex with CDK2, enzyme selectivity, and cellular effects.
Mettey Y; Gompel M; Thomas V; Garnier M; Leost M; Ceballos-Picot I; Noble M; Endicott J; Vierfond JM; Meijer L
J Med Chem; 2003 Jan; 46(2):222-36. PubMed ID: 12519061
[TBL] [Abstract][Full Text] [Related]
11. 2,5-Diaminopyrimidines and 3,5-disubstituted azapurines as inhibitors of glycogen synthase kinase-3 (GSK-3).
Lum C; Kahl J; Kessler L; Kucharski J; Lundström J; Miller S; Nakanishi H; Pei Y; Pryor K; Roberts E; Sebo L; Sullivan R; Urban J; Wang Z
Bioorg Med Chem Lett; 2008 Jun; 18(12):3578-81. PubMed ID: 18502127
[TBL] [Abstract][Full Text] [Related]
12. Fragment and knowledge-based design of selective GSK-3beta inhibitors using virtual screening models.
Vadivelan S; Sinha BN; Tajne S; Jagarlapudi SA
Eur J Med Chem; 2009 Jun; 44(6):2361-71. PubMed ID: 18929433
[TBL] [Abstract][Full Text] [Related]
13. Identification of potential glycogen kinase-3 inhibitors by structure based virtual screening.
Dessalew N; Bharatam PV
Biophys Chem; 2007 Jul; 128(2-3):165-75. PubMed ID: 17482749
[TBL] [Abstract][Full Text] [Related]
14. Discovery of novel isothiazole inhibitors of the TrkA kinase: structure-activity relationship, computer modeling, optimization, and identification of highly potent antagonists.
Lippa B; Morris J; Corbett M; Kwan TA; Noe MC; Snow SL; Gant TG; Mangiaracina M; Coffey HA; Foster B; Knauth EA; Wessel MD
Bioorg Med Chem Lett; 2006 Jul; 16(13):3444-8. PubMed ID: 16632359
[TBL] [Abstract][Full Text] [Related]
15. N-Phenyl-4-pyrazolo[1,5-b]pyridazin-3-ylpyrimidin-2-amines as potent and selective inhibitors of glycogen synthase kinase 3 with good cellular efficacy.
Tavares FX; Boucheron JA; Dickerson SH; Griffin RJ; Preugschat F; Thomson SA; Wang TY; Zhou HQ
J Med Chem; 2004 Sep; 47(19):4716-30. PubMed ID: 15341487
[TBL] [Abstract][Full Text] [Related]
16. Cyclin-dependent kinase inhibitors.
Fischer PM; Endicott J; Meijer L
Prog Cell Cycle Res; 2003; 5():235-48. PubMed ID: 14593718
[TBL] [Abstract][Full Text] [Related]
17. Synthesis of new dipyrrolo- and furopyrrolopyrazinones related to tripentones and their biological evaluation as potential kinases (CDKs1-5, GSK-3) inhibitors.
Rochais C; Duc NV; Lescot E; Sopkova-de Oliveira Santos J; Bureau R; Meijer L; Dallemagne P; Rault S
Eur J Med Chem; 2009 Feb; 44(2):708-16. PubMed ID: 18586356
[TBL] [Abstract][Full Text] [Related]
18. Identification and in vitro evaluation of new leads as selective and competitive glycogen synthase kinase-3β inhibitors through ligand and structure based drug design.
Darshit BS; Balaji B; Rani P; Ramanathan M
J Mol Graph Model; 2014 Sep; 53():31-47. PubMed ID: 25064440
[TBL] [Abstract][Full Text] [Related]
19. Structural determinants of CDK4 inhibition and design of selective ATP competitive inhibitors.
McInnes C; Wang S; Anderson S; O'Boyle J; Jackson W; Kontopidis G; Meades C; Mezna M; Thomas M; Wood G; Lane DP; Fischer PM
Chem Biol; 2004 Apr; 11(4):525-34. PubMed ID: 15123247
[TBL] [Abstract][Full Text] [Related]
20. Novel GSK-3 inhibitors with improved cellular activity.
Peat AJ; Garrido D; Boucheron JA; Schweiker SL; Dickerson SH; Wilson JR; Wang TY; Thomson SA
Bioorg Med Chem Lett; 2004 May; 14(9):2127-30. PubMed ID: 15080993
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]