These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

247 related articles for article (PubMed ID: 16645164)

  • 1. Flanking HS-62.5 and 3' HS1, and regions upstream of the LCR, are not required for beta-globin transcription.
    Bender MA; Byron R; Ragoczy T; Telling A; Bulger M; Groudine M
    Blood; 2006 Aug; 108(4):1395-401. PubMed ID: 16645164
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cooperativeness of the higher chromatin structure of the beta-globin locus revealed by the deletion mutations of DNase I hypersensitive site 3 of the LCR.
    Fang X; Xiang P; Yin W; Stamatoyannopoulos G; Li Q
    J Mol Biol; 2007 Jan; 365(1):31-7. PubMed ID: 17056066
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeted deletion of 5'HS1 and 5'HS4 of the beta-globin locus control region reveals additive activity of the DNaseI hypersensitive sites.
    Bender MA; Roach JN; Halow J; Close J; Alami R; Bouhassira EE; Groudine M; Fiering SN
    Blood; 2001 Oct; 98(7):2022-7. PubMed ID: 11567985
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Individual LCR hypersensitive sites cooperate to generate an open chromatin domain spanning the human beta-globin locus.
    Li G; Lim KC; Engel JD; Bungert J
    Genes Cells; 1998 Jul; 3(7):415-29. PubMed ID: 9753424
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Description and targeted deletion of 5' hypersensitive site 5 and 6 of the mouse beta-globin locus control region.
    Bender MA; Reik A; Close J; Telling A; Epner E; Fiering S; Hardison R; Groudine M
    Blood; 1998 Dec; 92(11):4394-403. PubMed ID: 9834246
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Deletion of the core region of 5' HS2 of the mouse beta-globin locus control region reveals a distinct effect in comparison with human beta-globin transgenes.
    Hu X; Bulger M; Bender MA; Fields J; Groudine M; Fiering S
    Blood; 2006 Jan; 107(2):821-6. PubMed ID: 16189270
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Transvection-like interchromosomal interaction is not observed at the transcriptional level when tested in the Rosa26 locus in mouse.
    Tanimoto K; Matsuzaki H; Okamura E; Ushiki A; Fukamizu A; Engel JD
    PLoS One; 2019; 14(2):e0203099. PubMed ID: 30763343
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Multiple interactions between regulatory regions are required to stabilize an active chromatin hub.
    Patrinos GP; de Krom M; de Boer E; Langeveld A; Imam AM; Strouboulis J; de Laat W; Grosveld FG
    Genes Dev; 2004 Jun; 18(12):1495-509. PubMed ID: 15198986
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hypersensitive site 2 specifies a unique function within the human beta-globin locus control region to stimulate globin gene transcription.
    Bungert J; Tanimoto K; Patel S; Liu Q; Fear M; Engel JD
    Mol Cell Biol; 1999 Apr; 19(4):3062-72. PubMed ID: 10082573
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Beta-globin gene switching and DNase I sensitivity of the endogenous beta-globin locus in mice do not require the locus control region.
    Bender MA; Bulger M; Close J; Groudine M
    Mol Cell; 2000 Feb; 5(2):387-93. PubMed ID: 10882079
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The human β-globin enhancer LCR HS2 plays a role in forming a TAD by activating chromatin structure at neighboring CTCF sites.
    Kim J; Kang J; Kim YW; Kim A
    FASEB J; 2021 Jun; 35(6):e21669. PubMed ID: 34033138
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Locus control region mediated regulation of adult beta-globin gene expression.
    Liang S; Moghimi B; Yang TP; Strouboulis J; Bungert J
    J Cell Biochem; 2008 Sep; 105(1):9-16. PubMed ID: 18500726
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The beta -globin locus control region (LCR) functions primarily by enhancing the transition from transcription initiation to elongation.
    Sawado T; Halow J; Bender MA; Groudine M
    Genes Dev; 2003 Apr; 17(8):1009-18. PubMed ID: 12672691
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Histone acetylation contributes to chromatin looping between the locus control region and globin gene by influencing hypersensitive site formation.
    Kim YW; Kim A
    Biochim Biophys Acta; 2013 Sep; 1829(9):963-9. PubMed ID: 23607989
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Chromatin structure at the flanking regions of the human beta-globin locus control region DNase I hypersensitive site-2: proposed nucleosome positioning by DNA-binding proteins including GATA-1.
    Davies N; Freebody J; Murray V
    Biochim Biophys Acta; 2004 Sep; 1679(3):201-13. PubMed ID: 15358512
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Human beta-globin locus control region HS5 contains CTCF- and developmental stage-dependent enhancer-blocking activity in erythroid cells.
    Tanimoto K; Sugiura A; Omori A; Felsenfeld G; Engel JD; Fukamizu A
    Mol Cell Biol; 2003 Dec; 23(24):8946-52. PubMed ID: 14645507
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nuclear localization and histone acetylation: a pathway for chromatin opening and transcriptional activation of the human beta-globin locus.
    Schübeler D; Francastel C; Cimbora DM; Reik A; Martin DI; Groudine M
    Genes Dev; 2000 Apr; 14(8):940-50. PubMed ID: 10783166
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The human beta-globin locus control region can silence as well as activate gene expression.
    Feng YQ; Warin R; Li T; Olivier E; Besse A; Lobell A; Fu H; Lin CM; Aladjem MI; Bouhassira EE
    Mol Cell Biol; 2005 May; 25(10):3864-74. PubMed ID: 15870261
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The murine beta-globin locus control region regulates the rate of transcription but not the hyperacetylation of histones at the active genes.
    Schübeler D; Groudine M; Bender MA
    Proc Natl Acad Sci U S A; 2001 Sep; 98(20):11432-7. PubMed ID: 11553791
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Independent formation of DnaseI hypersensitive sites in the murine beta-globin locus control region.
    Bender MA; Mehaffey MG; Telling A; Hug B; Ley TJ; Groudine M; Fiering S
    Blood; 2000 Jun; 95(11):3600-4. PubMed ID: 10828050
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.