137 related articles for article (PubMed ID: 16645883)
1. Fresh frozen plasma and platelet concentrates may increase plasma anti-diphtheria toxin IgG concentrations: Implications for diphtheria fusion protein therapy.
Hall PD; Sinha D; Frankel AE
Cancer Immunol Immunother; 2006 Aug; 55(8):928-32. PubMed ID: 16645883
[TBL] [Abstract][Full Text] [Related]
2. The majority of children and adolescents with acute myeloid leukemia have detectable anti-DT388-GMCSF IgG concentrations, but at concentrations that should not preclude in vivo activity.
Hall PD; Razzouk BI; Willoughby TE; McLean TW; Frankel AE
J Pediatr Hematol Oncol; 2002 Oct; 24(7):521-6. PubMed ID: 12368687
[TBL] [Abstract][Full Text] [Related]
3. Reducing anti-DT IgG concentrations to improve the efficacy of a diphtheria fusion protein.
Hall PD; Beagle KL; Garrett-Mayer E; Frankel AE
Anticancer Drugs; 2008 Nov; 19(10):1007-11. PubMed ID: 18827566
[TBL] [Abstract][Full Text] [Related]
4. Diphtheria toxin-interleukin-3 fusion protein (DT(388)IL3) prolongs disease-free survival of leukemic immunocompromised mice.
Black JH; McCubrey JA; Willingham MC; Ramage J; Hogge DE; Frankel AE
Leukemia; 2003 Jan; 17(1):155-9. PubMed ID: 12529673
[TBL] [Abstract][Full Text] [Related]
5. Phase I trial of a novel diphtheria toxin/granulocyte macrophage colony-stimulating factor fusion protein (DT388GMCSF) for refractory or relapsed acute myeloid leukemia.
Frankel AE; Powell BL; Hall PD; Case LD; Kreitman RJ
Clin Cancer Res; 2002 May; 8(5):1004-13. PubMed ID: 12006512
[TBL] [Abstract][Full Text] [Related]
6. Toxicology and pharmacokinetics of DT388IL3, a fusion toxin consisting of a truncated diphtheria toxin (DT388) linked to human interleukin 3 (IL3), in cynomolgus monkeys.
Cohen KA; Liu TF; Cline JM; Wagner JD; Hall PD; Frankel AE
Leuk Lymphoma; 2004 Aug; 45(8):1647-56. PubMed ID: 15370220
[TBL] [Abstract][Full Text] [Related]
7. Toxicology and pharmacokinetics of DT388-GM-CSF, a fusion toxin consisting of a truncated diphtheria toxin (DT388) linked to human granulocyte-macrophage colony-stimulating factor (GM-CSF) in C57BL/6 mice.
Hall PD; Kreitman RJ; Willingham MC; Frankel AE
Toxicol Appl Pharmacol; 1998 May; 150(1):91-7. PubMed ID: 9630457
[TBL] [Abstract][Full Text] [Related]
8. Malignant progenitors from patients with acute myelogenous leukemia are sensitive to a diphtheria toxin-granulocyte-macrophage colony-stimulating factor fusion protein.
Hogge DE; Willman CL; Kreitman RJ; Berger M; Hall PD; Kopecky KJ; McLain C; Tagge EP; Eaves CJ; Frankel AE
Blood; 1998 Jul; 92(2):589-95. PubMed ID: 9657759
[TBL] [Abstract][Full Text] [Related]
9. Recombinant toxins containing human granulocyte-macrophage colony-stimulating factor and either pseudomonas exotoxin or diphtheria toxin kill gastrointestinal cancer and leukemia cells.
Kreitman RJ; Pastan I
Blood; 1997 Jul; 90(1):252-9. PubMed ID: 9207460
[TBL] [Abstract][Full Text] [Related]
10. Safety evaluation of DT388IL3, a diphtheria toxin/interleukin 3 fusion protein, in the cynomolgus monkey.
Cohen KA; Liu TF; Cline JM; Wagner JD; Hall PD; Frankel AE
Cancer Immunol Immunother; 2005 Aug; 54(8):799-806. PubMed ID: 15614527
[TBL] [Abstract][Full Text] [Related]
11. Cytotoxic activities of recombinant immunotoxins composed of Pseudomonas toxin or diphtheria toxin toward lymphocytes from patients with adult T-cell leukemia.
Kreitman RJ; Chaudhary VK; Waldmann TA; Hanchard B; Cranston B; FitzGerald DJ; Pastan I
Leukemia; 1993 Apr; 7(4):553-62. PubMed ID: 8464234
[TBL] [Abstract][Full Text] [Related]
12. DT388-GM-CSF, a novel fusion toxin consisting of a truncated diphtheria toxin fused to human granulocyte-macrophage colony-stimulating factor, prolongs host survival in a SCID mouse model of acute myeloid leukemia.
Hall PD; Willingham MC; Kreitman RJ; Frankel AE
Leukemia; 1999 Apr; 13(4):629-33. PubMed ID: 10214872
[TBL] [Abstract][Full Text] [Related]
13. Recombinant single-chain immunotoxins against T and B cell leukemias.
Kreitman RJ; Pastan I
Leuk Lymphoma; 1994 Mar; 13(1-2):1-10. PubMed ID: 8025511
[TBL] [Abstract][Full Text] [Related]
14. Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor is toxic to blasts from patients with juvenile myelomonocytic leukemia and chronic myelomonocytic leukemia.
Frankel AE; Lilly M; Kreitman R; Hogge D; Beran M; Freedman MH; Emanuel PD; McLain C; Hall P; Tagge E; Berger M; Eaves C
Blood; 1998 Dec; 92(11):4279-86. PubMed ID: 9834234
[TBL] [Abstract][Full Text] [Related]
15. Antibody response to DT-GM, a novel fusion toxin consisting of a truncated diphtheria toxin (DT) linked to human granulocyte-macrophage colony stimulating factor (GM), during a phase I trial of patients with relapsed or refractory acute myeloid leukemia.
Hall PD; Virella G; Willoughby T; Atchley DH; Kreitman RJ; Frankel AE
Clin Immunol; 2001 Aug; 100(2):191-7. PubMed ID: 11465948
[TBL] [Abstract][Full Text] [Related]
16. The efficacy of diphtheria-growth factor fusion proteins is enhanced by co-administration of cytosine arabinoside in an immunodeficient mouse model of human acute myeloid leukemia.
Hogge DE; Feuring-Buske M; Gerhard B; Frankel AE
Leuk Res; 2004 Nov; 28(11):1221-6. PubMed ID: 15380349
[TBL] [Abstract][Full Text] [Related]
17. Cell-specific modulation of drug resistance in acute myeloid leukemic blasts by diphtheria fusion toxin, DT388-GMCSF.
Frankel AE; Hall PD; McLain C; Safa AR; Tagge EP; Kreitman RJ
Bioconjug Chem; 1998; 9(4):490-6. PubMed ID: 9667951
[TBL] [Abstract][Full Text] [Related]
18. Variable cytotoxicity of diphtheria toxin 388-granulocyte-macrophage colony-stimulating factor fusion protein for acute myelogenous leukemia stem cells.
Feuring-Buske M; Frankel A; Gerhard B; Hogge D
Exp Hematol; 2000 Dec; 28(12):1390-400. PubMed ID: 11146161
[TBL] [Abstract][Full Text] [Related]
19. A diphtheria toxin-interleukin 3 fusion protein is cytotoxic to primitive acute myeloid leukemia progenitors but spares normal progenitors.
Feuring-Buske M; Frankel AE; Alexander RL; Gerhard B; Hogge DE
Cancer Res; 2002 Mar; 62(6):1730-6. PubMed ID: 11912147
[TBL] [Abstract][Full Text] [Related]
20. A recombinant fusion toxin targeted to the granulocyte-macrophage colony-stimulating factor receptor.
Bendel AE; Shao Y; Davies SM; Warman B; Yang CH; Waddick KG; Uckun FM; Perentesis JP
Leuk Lymphoma; 1997 Apr; 25(3-4):257-70. PubMed ID: 9168436
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
