BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

172 related articles for article (PubMed ID: 16650989)

  • 1. SAR studies of 2-methoxyestradiol and development of its analogs as probes of anti-tumor mechanisms.
    Ho A; Kim YE; Lee H; Cyrus K; Baek SH; Kim KB
    Bioorg Med Chem Lett; 2006 Jul; 16(13):3383-7. PubMed ID: 16650989
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and structure-activity relationships of 16-modified analogs of 2-methoxyestradiol.
    Agoston GE; Shah JH; Lavallee TM; Zhan X; Pribluda VS; Treston AM
    Bioorg Med Chem; 2007 Dec; 15(24):7524-37. PubMed ID: 17910916
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effects of altering the electronics of 2-methoxyestradiol on cell proliferation, on cytotoxicity in human cancer cell cultures, and on tubulin polymerization.
    Edsall AB; Mohanakrishnan AK; Yang D; Fanwick PE; Hamel E; Hanson AD; Agoston GE; Cushman M
    J Med Chem; 2004 Oct; 47(21):5126-39. PubMed ID: 15456256
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 2-Methoxyestradiol and multidrug resistance: can 2-methoxyestradiol chemosensitize resistant breast cancer cells?
    Azab SS; Salama SA; Abdel-Naim AB; Khalifa AE; El-Demerdash E; Al-Hendy A
    Breast Cancer Res Treat; 2009 Jan; 113(1):9-19. PubMed ID: 18228136
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Chemotherapy of breast cancer-additive anticancerogenic effects by 2-methoxyestradiol?
    Mueck AO; Seeger H; Huober J
    Life Sci; 2004 Jul; 75(10):1205-10. PubMed ID: 15219808
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 2-Methoxyestradiol--biology and mechanism of action.
    Mueck AO; Seeger H
    Steroids; 2010 Oct; 75(10):625-31. PubMed ID: 20214913
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and antimitotic activity of novel 2-methoxyestradiol analogs--Part II.
    Rao PN; Cessac JW; Boyd JW; Hanson AD; Shah J
    Steroids; 2008 Feb; 73(2):158-70. PubMed ID: 18155740
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Isolation, synthesis, and anti-tumor activities of a novel class of podocarpic diterpenes.
    Xiong Y; Wang K; Pan Y; Sun H; Tu J
    Bioorg Med Chem Lett; 2006 Feb; 16(4):786-9. PubMed ID: 16309905
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis, antitubulin, and antiproliferative SAR of analogues of 2-methoxyestradiol-3,17-O,O-bis-sulfamate.
    Jourdan F; Leese MP; Dohle W; Hamel E; Ferrandis E; Newman SP; Purohit A; Reed MJ; Potter BV
    J Med Chem; 2010 Apr; 53(7):2942-51. PubMed ID: 20225862
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and in vivo antitumor evaluation of 2-methoxyestradiol 3-phosphate, 17-phosphate, and 3,17-diphosphate.
    Edsall AB; Agoston GE; Treston AM; Plum SM; McClanahan RH; Lu TS; Song W; Cushman M
    J Med Chem; 2007 Dec; 50(26):6700-5. PubMed ID: 18052315
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure-activity relationships of C-17 cyano-substituted estratrienes as anticancer agents.
    Leese MP; Jourdan FL; Gaukroger K; Mahon MF; Newman SP; Foster PA; Stengel C; Regis-Lydi S; Ferrandis E; Di Fiore A; De Simone G; Supuran CT; Purohit A; Reed MJ; Potter BV
    J Med Chem; 2008 Mar; 51(5):1295-308. PubMed ID: 18260615
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Preliminary SAR analysis of novel antiproliferative N(6),5'-bis-ureidoadenosine derivatives.
    Peterson MA; Oliveira M; Christiansen MA; Cutler CE
    Bioorg Med Chem Lett; 2009 Dec; 19(23):6775-9. PubMed ID: 19850476
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Substituted quinazolines, part 3. Synthesis, in vitro antitumor activity and molecular modeling study of certain 2-thieno-4(3H)-quinazolinone analogs.
    Al-Obaid AM; Abdel-Hamide SG; El-Kashef HA; Abdel-Aziz AA; El-Azab AS; Al-Khamees HA; El-Subbagh HI
    Eur J Med Chem; 2009 Jun; 44(6):2379-91. PubMed ID: 18950904
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 2-Methoxyestradiol induce the conversion of human peripheral blood memory B lymphocytes into plasma cells.
    Cayer MP; Drouin M; Proulx M; Jung D
    J Immunol Methods; 2010 Apr; 355(1-2):29-39. PubMed ID: 20202470
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis of indirubin-N'-glycosides and their anti-proliferative activity against human cancer cell lines.
    Libnow S; Methling K; Hein M; Michalik D; Harms M; Wende K; Flemming A; Köckerling M; Reinke H; Bednarski PJ; Lalk M; Langer P
    Bioorg Med Chem; 2008 May; 16(10):5570-83. PubMed ID: 18434163
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design and synthesis of a biotinylated probe of COX-2 inhibitor nimesulide analog JCC76.
    Zhong B; Lama R; Smith KM; Xu Y; Su B
    Bioorg Med Chem Lett; 2011 Sep; 21(18):5324-7. PubMed ID: 21807508
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evidence that 2-methoxyestradiol suppresses proliferation and accelerates apoptosis in normal rat growth plate chondrocytes.
    Sibonga JD; Sommer U; Turner RT
    J Cancer Res Clin Oncol; 2002 Sep; 128(9):477-83. PubMed ID: 12242511
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, antiproliferative, and pharmacokinetic properties of 3- and 17-double-modified analogs of 2-methoxyestradiol.
    Agoston GE; Shah JH; Suwandi L; Hanson AD; Zhan X; LaVallee TM; Pribluda V; Treston AM
    Bioorg Med Chem Lett; 2009 Nov; 19(21):6241-4. PubMed ID: 19782564
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A-ring-substituted estrogen-3-O-sulfamates: potent multitargeted anticancer agents.
    Leese MP; Hejaz HA; Mahon MF; Newman SP; Purohit A; Reed MJ; Potter BV
    J Med Chem; 2005 Aug; 48(16):5243-56. PubMed ID: 16078843
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 2-Methoxyestradiol suppresses osteolytic breast cancer tumor progression in vivo.
    Cicek M; Iwaniec UT; Goblirsch MJ; Vrabel A; Ruan M; Clohisy DR; Turner RR; Oursler MJ
    Cancer Res; 2007 Nov; 67(21):10106-11. PubMed ID: 17974950
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.