BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

245 related articles for article (PubMed ID: 16675548)

  • 1. Crystal structure of the SOCS2-elongin C-elongin B complex defines a prototypical SOCS box ubiquitin ligase.
    Bullock AN; Debreczeni JE; Edwards AM; Sundström M; Knapp S
    Proc Natl Acad Sci U S A; 2006 May; 103(20):7637-42. PubMed ID: 16675548
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure of the SOCS4-ElonginB/C complex reveals a distinct SOCS box interface and the molecular basis for SOCS-dependent EGFR degradation.
    Bullock AN; Rodriguez MC; Debreczeni JE; Songyang Z; Knapp S
    Structure; 2007 Nov; 15(11):1493-504. PubMed ID: 17997974
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Biophysical studies on interactions and assembly of full-size E3 ubiquitin ligase: suppressor of cytokine signaling 2 (SOCS2)-elongin BC-cullin 5-ring box protein 2 (RBX2).
    Bulatov E; Martin EM; Chatterjee S; Knebel A; Shimamura S; Konijnenberg A; Johnson C; Zinn N; Grandi P; Sobott F; Ciulli A
    J Biol Chem; 2015 Feb; 290(7):4178-91. PubMed ID: 25505247
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural basis of intersubunit recognition in elongin BC-cullin 5-SOCS box ubiquitin-protein ligase complexes.
    Kim YK; Kwak MJ; Ku B; Suh HY; Joo K; Lee J; Jung JU; Oh BH
    Acta Crystallogr D Biol Crystallogr; 2013 Aug; 69(Pt 8):1587-97. PubMed ID: 23897481
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular architecture of the ankyrin SOCS box family of Cul5-dependent E3 ubiquitin ligases.
    Muniz JR; Guo K; Kershaw NJ; Ayinampudi V; von Delft F; Babon JJ; Bullock AN
    J Mol Biol; 2013 Sep; 425(17):3166-77. PubMed ID: 23806657
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Multimeric complexes among ankyrin-repeat and SOCS-box protein 9 (ASB9), ElonginBC, and Cullin 5: insights into the structure and assembly of ECS-type Cullin-RING E3 ubiquitin ligases.
    Thomas JC; Matak-Vinkovic D; Van Molle I; Ciulli A
    Biochemistry; 2013 Aug; 52(31):5236-46. PubMed ID: 23837592
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The SOCS box domain of SOCS3: structure and interaction with the elonginBC-cullin5 ubiquitin ligase.
    Babon JJ; Sabo JK; Soetopo A; Yao S; Bailey MF; Zhang JG; Nicola NA; Norton RS
    J Mol Biol; 2008 Sep; 381(4):928-40. PubMed ID: 18590740
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families.
    Kamura T; Sato S; Haque D; Liu L; Kaelin WG; Conaway RC; Conaway JW
    Genes Dev; 1998 Dec; 12(24):3872-81. PubMed ID: 9869640
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Muf1, a novel Elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase.
    Kamura T; Burian D; Yan Q; Schmidt SL; Lane WS; Querido E; Branton PE; Shilatifard A; Conaway RC; Conaway JW
    J Biol Chem; 2001 Aug; 276(32):29748-53. PubMed ID: 11384984
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of SOCS and VHL Proteins in Neuronal Differentiation and Development.
    Kanno H; Matsumoto S; Yoshizumi T; Nakahara K; Kubo A; Murata H; Shuin T; U HS
    Int J Mol Sci; 2023 Feb; 24(4):. PubMed ID: 36835292
    [TBL] [Abstract][Full Text] [Related]  

  • 11. VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases.
    Kamura T; Maenaka K; Kotoshiba S; Matsumoto M; Kohda D; Conaway RC; Conaway JW; Nakayama KI
    Genes Dev; 2004 Dec; 18(24):3055-65. PubMed ID: 15601820
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The SOCS2 ubiquitin ligase complex regulates growth hormone receptor levels.
    Vesterlund M; Zadjali F; Persson T; Nielsen ML; Kessler BM; Norstedt G; Flores-Morales A
    PLoS One; 2011; 6(9):e25358. PubMed ID: 21980433
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of Elongin C and Skp1 sequences that determine Cullin selection.
    Yan Q; Kamura T; Cai Y; Jin J; Ivan M; Mushegian A; Conaway RC; Conaway JW
    J Biol Chem; 2004 Oct; 279(41):43019-26. PubMed ID: 15280393
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The SOCS-box of HIV-1 Vif interacts with ElonginBC by induced-folding to recruit its Cul5-containing ubiquitin ligase complex.
    Bergeron JR; Huthoff H; Veselkov DA; Beavil RL; Simpson PJ; Matthews SJ; Malim MH; Sanderson MR
    PLoS Pathog; 2010 Jun; 6(6):e1000925. PubMed ID: 20532212
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2.
    Kamizono S; Hanada T; Yasukawa H; Minoguchi S; Kato R; Minoguchi M; Hattori K; Hatakeyama S; Yada M; Morita S; Kitamura T; Kato H; Nakayama Ki ; Yoshimura A
    J Biol Chem; 2001 Apr; 276(16):12530-8. PubMed ID: 11278610
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of Cullin-box sequences that direct recruitment of Cul2-Rbx1 and Cul5-Rbx2 modules to Elongin BC-based ubiquitin ligases.
    Mahrour N; Redwine WB; Florens L; Swanson SK; Martin-Brown S; Bradford WD; Staehling-Hampton K; Washburn MP; Conaway RC; Conaway JW
    J Biol Chem; 2008 Mar; 283(12):8005-13. PubMed ID: 18187417
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Functional cross-modulation between SOCS proteins can stimulate cytokine signaling.
    Piessevaux J; Lavens D; Montoye T; Wauman J; Catteeuw D; Vandekerckhove J; Belsham D; Peelman F; Tavernier J
    J Biol Chem; 2006 Nov; 281(44):32953-66. PubMed ID: 16956890
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mammalian mediator subunit mMED8 is an Elongin BC-interacting protein that can assemble with Cul2 and Rbx1 to reconstitute a ubiquitin ligase.
    Brower CS; Sato S; Tomomori-Sato C; Kamura T; Pause A; Stearman R; Klausner RD; Malik S; Lane WS; Sorokina I; Roeder RG; Conaway JW; Conaway RC
    Proc Natl Acad Sci U S A; 2002 Aug; 99(16):10353-8. PubMed ID: 12149480
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The E3 ubiquitin ligase HOIL-1 induces the polyubiquitination and degradation of SOCS6 associated proteins.
    Bayle J; Lopez S; Iwaï K; Dubreuil P; De Sepulveda P
    FEBS Lett; 2006 May; 580(11):2609-14. PubMed ID: 16643902
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Insight into the HIV-1 Vif SOCS-box-ElonginBC interaction.
    Lu Z; Bergeron JR; Atkinson RA; Schaller T; Veselkov DA; Oregioni A; Yang Y; Matthews SJ; Malim MH; Sanderson MR
    Open Biol; 2013 Nov; 3(11):130100. PubMed ID: 24225024
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.