265 related articles for article (PubMed ID: 16679292)
1. Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKClambda/zeta.
Taniguchi CM; Kondo T; Sajan M; Luo J; Bronson R; Asano T; Farese R; Cantley LC; Kahn CR
Cell Metab; 2006 May; 3(5):343-53. PubMed ID: 16679292
[TBL] [Abstract][Full Text] [Related]
2. Coordinated regulation of hepatic FoxO1, PGC-1α and SREBP-1c facilitates insulin action and resistance.
Sajan MP; Lee MC; Foufelle F; Sajan J; Cleland C; Farese RV
Cell Signal; 2018 Mar; 43():62-70. PubMed ID: 29269047
[TBL] [Abstract][Full Text] [Related]
3. PKClambda in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity.
Matsumoto M; Ogawa W; Akimoto K; Inoue H; Miyake K; Furukawa K; Hayashi Y; Iguchi H; Matsuki Y; Hiramatsu R; Shimano H; Yamada N; Ohno S; Kasuga M; Noda T
J Clin Invest; 2003 Sep; 112(6):935-44. PubMed ID: 12975478
[TBL] [Abstract][Full Text] [Related]
4. PKCλ haploinsufficiency prevents diabetes by a mechanism involving alterations in hepatic enzymes.
Sajan MP; Ivey RA; Lee M; Mastorides S; Jurczak MJ; Samuels VT; Shulman GI; Braun U; Leitges M; Farese RV
Mol Endocrinol; 2014 Jul; 28(7):1097-107. PubMed ID: 24877563
[TBL] [Abstract][Full Text] [Related]
5. The critical role of atypical protein kinase C in activating hepatic SREBP-1c and NFkappaB in obesity.
Sajan MP; Standaert ML; Nimal S; Varanasi U; Pastoor T; Mastorides S; Braun U; Leitges M; Farese RV
J Lipid Res; 2009 Jun; 50(6):1133-45. PubMed ID: 19202134
[TBL] [Abstract][Full Text] [Related]
6. Specific roles of the p110alpha isoform of phosphatidylinsositol 3-kinase in hepatic insulin signaling and metabolic regulation.
Sopasakis VR; Liu P; Suzuki R; Kondo T; Winnay J; Tran TT; Asano T; Smyth G; Sajan MP; Farese RV; Kahn CR; Zhao JJ
Cell Metab; 2010 Mar; 11(3):220-30. PubMed ID: 20197055
[TBL] [Abstract][Full Text] [Related]
7. Long Noncoding RNA lncSHGL Recruits hnRNPA1 to Suppress Hepatic Gluconeogenesis and Lipogenesis.
Wang J; Yang W; Chen Z; Chen J; Meng Y; Feng B; Sun L; Dou L; Li J; Cui Q; Yang J
Diabetes; 2018 Apr; 67(4):581-593. PubMed ID: 29382663
[TBL] [Abstract][Full Text] [Related]
8. Irisin inhibits hepatic gluconeogenesis and increases glycogen synthesis via the PI3K/Akt pathway in type 2 diabetic mice and hepatocytes.
Liu TY; Shi CX; Gao R; Sun HJ; Xiong XQ; Ding L; Chen Q; Li YH; Wang JJ; Kang YM; Zhu GQ
Clin Sci (Lond); 2015 Nov; 129(10):839-50. PubMed ID: 26201094
[TBL] [Abstract][Full Text] [Related]
9. Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c.
Hagiwara A; Cornu M; Cybulski N; Polak P; Betz C; Trapani F; Terracciano L; Heim MH; Rüegg MA; Hall MN
Cell Metab; 2012 May; 15(5):725-38. PubMed ID: 22521878
[TBL] [Abstract][Full Text] [Related]
10. Insulin-stimulated protein kinase C lambda/zeta activity is reduced in skeletal muscle of humans with obesity and type 2 diabetes: reversal with weight reduction.
Kim YB; Kotani K; Ciaraldi TP; Henry RR; Kahn BB
Diabetes; 2003 Aug; 52(8):1935-42. PubMed ID: 12882908
[TBL] [Abstract][Full Text] [Related]
11. Dominant negative forms of Akt (protein kinase B) and atypical protein kinase Clambda do not prevent insulin inhibition of phosphoenolpyruvate carboxykinase gene transcription.
Kotani K; Ogawa W; Hino Y; Kitamura T; Ueno H; Sano W; Sutherland C; Granner DK; Kasuga M
J Biol Chem; 1999 Jul; 274(30):21305-12. PubMed ID: 10409689
[TBL] [Abstract][Full Text] [Related]
12. Prolonged high-glucose exposure decreased SREBP-1/FASN/ACC in Schwann cells of diabetic mice via blocking PI3K/Akt pathway.
Zhu L; Du W; Liu Y; Cheng M; Wang X; Zhang C; Lv X; Li F; Zhao S; Hao J
J Cell Biochem; 2019 Apr; 120(4):5777-5789. PubMed ID: 30362584
[TBL] [Abstract][Full Text] [Related]
13. PTEN influences insulin and lipid metabolism in bovine hepatocytes in vitro.
Deng Q; Ma D; Sun G; Yuan X; Wang Z; Liu G
J Dairy Res; 2019 Feb; 86(1):73-76. PubMed ID: 30819264
[TBL] [Abstract][Full Text] [Related]
14. A bioinformatics and transcriptomics based investigation reveals an inhibitory role of Huanglian-Renshen-Decoction on hepatic glucose production of T2DM mice via PI3K/Akt/FoxO1 signaling pathway.
Wu F; Shao Q; Xia Q; Hu M; Zhao Y; Wang D; Fang K; Xu L; Zou X; Chen Z; Chen G; Lu F
Phytomedicine; 2021 Mar; 83():153487. PubMed ID: 33636476
[TBL] [Abstract][Full Text] [Related]
15. Insulin enhances post-translational processing of nascent SREBP-1c by promoting its phosphorylation and association with COPII vesicles.
Yellaturu CR; Deng X; Cagen LM; Wilcox HG; Mansbach CM; Siddiqi SA; Park EA; Raghow R; Elam MB
J Biol Chem; 2009 Mar; 284(12):7518-32. PubMed ID: 19158095
[TBL] [Abstract][Full Text] [Related]
16. Insulin-sensitive protein kinases (atypical protein kinase C and protein kinase B/Akt): actions and defects in obesity and type II diabetes.
Farese RV; Sajan MP; Standaert ML
Exp Biol Med (Maywood); 2005 Oct; 230(9):593-605. PubMed ID: 16179727
[TBL] [Abstract][Full Text] [Related]
17. MicroRNA-351 eases insulin resistance and liver gluconeogenesis via the PI3K/AKT pathway by inhibiting FLOT2 in mice of gestational diabetes mellitus.
Chen SH; Liu XN; Peng Y
J Cell Mol Med; 2019 Sep; 23(9):5895-5906. PubMed ID: 31287224
[TBL] [Abstract][Full Text] [Related]
18. PI3K-C2γ is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling.
Braccini L; Ciraolo E; Campa CC; Perino A; Longo DL; Tibolla G; Pregnolato M; Cao Y; Tassone B; Damilano F; Laffargue M; Calautti E; Falasca M; Norata GD; Backer JM; Hirsch E
Nat Commun; 2015 Jun; 6():7400. PubMed ID: 26100075
[TBL] [Abstract][Full Text] [Related]
19. Glycine N-methyltransferase deficiency in female mice impairs insulin signaling and promotes gluconeogenesis by modulating the PI3K/Akt pathway in the liver.
Liao YJ; Lee TS; Twu YC; Hsu SM; Yang CP; Wang CK; Liang YC; Chen YA
J Biomed Sci; 2016 Oct; 23(1):69. PubMed ID: 27716281
[TBL] [Abstract][Full Text] [Related]
20. Hepatic Akt activation induces marked hypoglycemia, hepatomegaly, and hypertriglyceridemia with sterol regulatory element binding protein involvement.
Ono H; Shimano H; Katagiri H; Yahagi N; Sakoda H; Onishi Y; Anai M; Ogihara T; Fujishiro M; Viana AY; Fukushima Y; Abe M; Shojima N; Kikuchi M; Yamada N; Oka Y; Asano T
Diabetes; 2003 Dec; 52(12):2905-13. PubMed ID: 14633850
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
