BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

433 related articles for article (PubMed ID: 16680870)

  • 21. Characterization of dextromethorphan N-demethylation by human liver microsomes. Contribution of the cytochrome P450 3A (CYP3A) subfamily.
    Gorski JC; Jones DR; Wrighton SA; Hall SD
    Biochem Pharmacol; 1994 Jul; 48(1):173-82. PubMed ID: 8043020
    [TBL] [Abstract][Full Text] [Related]  

  • 22. The gastroprokinetic and antiemetic drug metoclopramide is a substrate and inhibitor of cytochrome P450 2D6.
    Desta Z; Wu GM; Morocho AM; Flockhart DA
    Drug Metab Dispos; 2002 Mar; 30(3):336-43. PubMed ID: 11854155
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Mechanism-based inactivation of human liver cytochrome P450 2A6 by 8-methoxypsoralen.
    Koenigs LL; Peter RM; Thompson SJ; Rettie AE; Trager WF
    Drug Metab Dispos; 1997 Dec; 25(12):1407-15. PubMed ID: 9394031
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Cannabidiol, a major phytocannabinoid, as a potent atypical inhibitor for CYP2D6.
    Yamaori S; Okamoto Y; Yamamoto I; Watanabe K
    Drug Metab Dispos; 2011 Nov; 39(11):2049-56. PubMed ID: 21821735
    [TBL] [Abstract][Full Text] [Related]  

  • 25. 2,5-Dimethoxyamphetamine-derived designer drugs: studies on the identification of cytochrome P450 (CYP) isoenzymes involved in formation of their main metabolites and on their capability to inhibit CYP2D6.
    Ewald AH; Maurer HH
    Toxicol Lett; 2008 Dec; 183(1-3):52-7. PubMed ID: 18938231
    [TBL] [Abstract][Full Text] [Related]  

  • 26. In vitro metabolism of the calmodulin antagonist DY-9760e (3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate) by human liver microsomes: involvement of cytochromes p450 in atypical kinetics and potential drug interactions.
    Tachibana S; Fujimaki Y; Yokoyama H; Okazaki O; Sudo K
    Drug Metab Dispos; 2005 Nov; 33(11):1628-36. PubMed ID: 16049129
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Mechanism-based inactivation of CYP2D6 by methylenedioxymethamphetamine.
    Heydari A; Yeo KR; Lennard MS; Ellis SW; Tucker GT; Rostami-Hodjegan A
    Drug Metab Dispos; 2004 Nov; 32(11):1213-7. PubMed ID: 15328252
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Metabolism of artelinic acid to dihydroqinqhaosu by human liver cytochrome P4503A.
    Grace JM; Skanchy DJ; Aguilar AJ
    Xenobiotica; 1999 Jul; 29(7):703-17. PubMed ID: 10456689
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Expression, purification, and characterization of mouse CYP2d22.
    Yu AM; Haining RL
    Drug Metab Dispos; 2006 Jul; 34(7):1167-74. PubMed ID: 16595712
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes.
    Lalovic B; Phillips B; Risler LL; Howald W; Shen DD
    Drug Metab Dispos; 2004 Apr; 32(4):447-54. PubMed ID: 15039299
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Dextromethorphan O-demethylation in liver microsomes as a prototype reaction to monitor cytochrome P-450 db1 activity.
    Dayer P; Leemann T; Striberni R
    Clin Pharmacol Ther; 1989 Jan; 45(1):34-40. PubMed ID: 2910636
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Stereoselective metabolism of cibenzoline, an antiarrhythmic drug, by human and rat liver microsomes: possible involvement of CYP2D and CYP3A.
    Niwa T; Shiraga T; Mitani Y; Terakawa M; Tokuma Y; Kagayama A
    Drug Metab Dispos; 2000 Sep; 28(9):1128-34. PubMed ID: 10950860
    [TBL] [Abstract][Full Text] [Related]  

  • 33. High-performance liquid chromatographic assays for bufuralol 1'-hydroxylase, debrisoquine 4-hydroxylase, and dextromethorphan O-demethylase in microsomes and purified cytochrome P-450 isozymes of human liver.
    Kronbach T; Mathys D; Gut J; Catin T; Meyer UA
    Anal Biochem; 1987 Apr; 162(1):24-32. PubMed ID: 3605590
    [TBL] [Abstract][Full Text] [Related]  

  • 34. In vitro evaluation of valproic acid as an inhibitor of human cytochrome P450 isoforms: preferential inhibition of cytochrome P450 2C9 (CYP2C9).
    Wen X; Wang JS; Kivistö KT; Neuvonen PJ; Backman JT
    Br J Clin Pharmacol; 2001 Nov; 52(5):547-53. PubMed ID: 11736863
    [TBL] [Abstract][Full Text] [Related]  

  • 35. [O-methyl 14C]naproxen O-demethylase activity in human liver microsomes: evidence for the involvement of cytochrome P4501A2 and P4502C9/10.
    Rodrigues AD; Kukulka MJ; Roberts EM; Ouellet D; Rodgers TR
    Drug Metab Dispos; 1996 Jan; 24(1):126-36. PubMed ID: 8825200
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Potent inhibition of cytochrome P-450 2D6-mediated dextromethorphan O-demethylation by terbinafine.
    Abdel-Rahman SM; Marcucci K; Boge T; Gotschall RR; Kearns GL; Leeder JS
    Drug Metab Dispos; 1999 Jul; 27(7):770-5. PubMed ID: 10383919
    [TBL] [Abstract][Full Text] [Related]  

  • 37. In vitro characterization of the drug-drug interaction potential of catabolites of antibody-maytansinoid conjugates.
    Davis JA; Rock DA; Wienkers LC; Pearson JT
    Drug Metab Dispos; 2012 Oct; 40(10):1927-34. PubMed ID: 22752008
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Identification of human cytochrome P450 enzymes involved in the major metabolic pathway of fluvoxamine.
    Miura M; Ohkubo T
    Xenobiotica; 2007 Feb; 37(2):169-79. PubMed ID: 17484519
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Effect of black seed on dextromethorphan O- and N-demethylation in human liver microsomes and healthy human subjects.
    Al-Jenoobi FI; Al-Thukair AA; Abbas FA; Ansari MJ; Alkharfy KM; Al-Mohizea AM; Al-Suwayeh SA; Jamil S
    Drug Metab Lett; 2010 Jan; 4(1):51-5. PubMed ID: 20201775
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Primary and secondary oxidative metabolism of dextromethorphan. In vitro studies with female Sprague-Dawley and Dark Agouti rat liver microsomes.
    Kerry NL; Somogyi AA; Mikus G; Bochner F
    Biochem Pharmacol; 1993 Feb; 45(4):833-9. PubMed ID: 8452558
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 22.