BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

233 related articles for article (PubMed ID: 16682254)

  • 1. Analysis of tumors arising in male B6C3F1 mice with and without AAV vector delivery to liver.
    Bell P; Moscioni AD; McCarter RJ; Wu D; Gao G; Hoang A; Sanmiguel JC; Sun X; Wivel NA; Raper SE; Furth EE; Batshaw ML; Wilson JM
    Mol Ther; 2006 Jul; 14(1):34-44. PubMed ID: 16682254
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Long-term correction of ammonia metabolism and prolonged survival in ornithine transcarbamylase-deficient mice following liver-directed treatment with adeno-associated viral vectors.
    Moscioni D; Morizono H; McCarter RJ; Stern A; Cabrera-Luque J; Hoang A; Sanmiguel J; Wu D; Bell P; Gao GP; Raper SE; Wilson JM; Batshaw ML
    Mol Ther; 2006 Jul; 14(1):25-33. PubMed ID: 16677864
    [TBL] [Abstract][Full Text] [Related]  

  • 3. No evidence for tumorigenesis of AAV vectors in a large-scale study in mice.
    Bell P; Wang L; Lebherz C; Flieder DB; Bove MS; Wu D; Gao GP; Wilson JM; Wivel NA
    Mol Ther; 2005 Aug; 12(2):299-306. PubMed ID: 16043099
    [TBL] [Abstract][Full Text] [Related]  

  • 4. AAV-encoded OTC activity persisting to adulthood following delivery to newborn spf(ash) mice is insufficient to prevent shRNA-induced hyperammonaemia.
    Cunningham SC; Kok CY; Spinoulas A; Carpenter KH; Alexander IE
    Gene Ther; 2013 Dec; 20(12):1184-7. PubMed ID: 24108150
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Adeno-associated virus-mediated delivery of IL-4 prevents collagen-induced arthritis.
    Cottard V; Mulleman D; Bouille P; Mezzina M; Boissier MC; Bessis N
    Gene Ther; 2000 Nov; 7(22):1930-9. PubMed ID: 11127581
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Vector-related tumorigenesis not found in ornithine transcarbamylase-deficient mice.
    Koeberl DD
    Mol Ther; 2006 Jul; 14(1):1-2. PubMed ID: 16750655
    [No Abstract]   [Full Text] [Related]  

  • 7. AAV gene therapy corrects OTC deficiency and prevents liver fibrosis in aged OTC-knock out heterozygous mice.
    Wang L; Bell P; Morizono H; He Z; Pumbo E; Yu H; White J; Batshaw ML; Wilson JM
    Mol Genet Metab; 2017 Apr; 120(4):299-305. PubMed ID: 28283349
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Increased efficacy and safety in the treatment of experimental liver cancer with a novel adenovirus-alphavirus hybrid vector.
    Guan M; Rodriguez-Madoz JR; Alzuguren P; Gomar C; Kramer MG; Kochanek S; Prieto J; Smerdou C; Qian C
    Cancer Res; 2006 Feb; 66(3):1620-9. PubMed ID: 16452221
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In vivo assessment of mutations in OTC for dominant-negative effects following rAAV2/8-mediated gene delivery to the mouse liver.
    Ginn SL; Cunningham SC; Zheng M; Spinoulas A; Carpenter KH; Alexander IE
    Gene Ther; 2009 Jun; 16(6):820-3. PubMed ID: 19357713
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Utility of intraperitoneal administration as a route of AAV serotype 5 vector-mediated neonatal gene transfer.
    Ogura T; Mizukami H; Mimuro J; Madoiwa S; Okada T; Matsushita T; Urabe M; Kume A; Hamada H; Yoshikawa H; Sakata Y; Ozawa K
    J Gene Med; 2006 Aug; 8(8):990-7. PubMed ID: 16685745
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transient depletion of CD4 lymphocyte improves efficacy of repeated administration of recombinant adenovirus in the ornithine transcarbamylase deficient sparse fur mouse.
    Ye X; Robinson MB; Pabin C; Batshaw ML; Wilson JM
    Gene Ther; 2000 Oct; 7(20):1761-7. PubMed ID: 11083498
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Observed incidence of tumorigenesis in long-term rodent studies of rAAV vectors.
    Donsante A; Vogler C; Muzyczka N; Crawford JM; Barker J; Flotte T; Campbell-Thompson M; Daly T; Sands MS
    Gene Ther; 2001 Sep; 8(17):1343-6. PubMed ID: 11571571
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Induction and prevention of severe hyperammonemia in the spfash mouse model of ornithine transcarbamylase deficiency using shRNA and rAAV-mediated gene delivery.
    Cunningham SC; Kok CY; Dane AP; Carpenter K; Kizana E; Kuchel PW; Alexander IE
    Mol Ther; 2011 May; 19(5):854-9. PubMed ID: 21386824
    [TBL] [Abstract][Full Text] [Related]  

  • 14. AAV serotype-1 mediates early onset of gene expression in mouse hearts and results in better therapeutic effect.
    Su H; Huang Y; Takagawa J; Barcena A; Arakawa-Hoyt J; Ye J; Grossman W; Kan YW
    Gene Ther; 2006 Nov; 13(21):1495-502. PubMed ID: 16775632
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Early, sustained efficacy of adeno-associated virus vector-mediated gene therapy in glycogen storage disease type Ia.
    Koeberl DD; Sun BD; Damodaran TV; Brown T; Millington DS; Benjamin DK; Bird A; Schneider A; Hillman S; Jackson M; Beaty RM; Chen YT
    Gene Ther; 2006 Sep; 13(17):1281-9. PubMed ID: 16672983
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In vivo high-efficiency transcoronary gene delivery and Cre-LoxP gene switching in the adult mouse heart.
    Iwatate M; Gu Y; Dieterle T; Iwanaga Y; Peterson KL; Hoshijima M; Chien KR; Ross J
    Gene Ther; 2003 Oct; 10(21):1814-20. PubMed ID: 12960971
    [TBL] [Abstract][Full Text] [Related]  

  • 17. AAV2/8-mediated correction of OTC deficiency is robust in adult but not neonatal Spf(ash) mice.
    Cunningham SC; Spinoulas A; Carpenter KH; Wilcken B; Kuchel PW; Alexander IE
    Mol Ther; 2009 Aug; 17(8):1340-6. PubMed ID: 19384294
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Correction of ornithine transcarbamylase deficiency in adult spf(ash) mice and in OTC-deficient human hepatocytes with recombinant adenoviruses bearing the CAG promoter.
    Kiwaki K; Kanegae Y; Saito I; Komaki S; Nakamura K; Miyazaki JI; Endo F; Matsuda I
    Hum Gene Ther; 1996 May; 7(7):821-30. PubMed ID: 8860834
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A single injection of double-stranded adeno-associated viral vector expressing GH normalizes growth in GH-deficient mice.
    Sagazio A; Xiao X; Wang Z; Martari M; Salvatori R
    J Endocrinol; 2008 Jan; 196(1):79-88. PubMed ID: 18180319
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Gene therapy with novel adeno-associated virus vectors substantially diminishes atherosclerosis in a murine model of familial hypercholesterolemia.
    Lebherz C; Gao G; Louboutin JP; Millar J; Rader D; Wilson JM
    J Gene Med; 2004 Jun; 6(6):663-72. PubMed ID: 15170737
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.