These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

247 related articles for article (PubMed ID: 16685645)

  • 1. Promoter mutations that increase amyloid precursor-protein expression are associated with Alzheimer disease.
    Theuns J; Brouwers N; Engelborghs S; Sleegers K; Bogaerts V; Corsmit E; De Pooter T; van Duijn CM; De Deyn PP; Van Broeckhoven C
    Am J Hum Genet; 2006 Jun; 78(6):936-46. PubMed ID: 16685645
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Genetic risk and transcriptional variability of amyloid precursor protein in Alzheimer's disease.
    Brouwers N; Sleegers K; Engelborghs S; Bogaerts V; Serneels S; Kamali K; Corsmit E; De Leenheir E; Martin JJ; De Deyn PP; Van Broeckhoven C; Theuns J
    Brain; 2006 Nov; 129(Pt 11):2984-91. PubMed ID: 16931535
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Relationship between single nucleotide polymorphisms in the 3'UTR of amyloid precursor protein and risk of Alzheimer's disease and its mechanism.
    Zhou Q; Luo L; Wang X; Li X
    Biosci Rep; 2019 May; 39(5):. PubMed ID: 30914454
    [No Abstract]   [Full Text] [Related]  

  • 4. The upstream stimulatory factor functionally interacts with the Alzheimer amyloid beta-protein precursor gene.
    Kovacs DM; Wasco W; Witherby J; Felsenstein KM; Brunel F; Roeder RG; Tanzi RE
    Hum Mol Genet; 1995 Sep; 4(9):1527-33. PubMed ID: 8541835
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanism of promoter activity of the beta-amyloid precursor protein gene in different cell lines: identification of a specific 30 bp fragment in the proximal promoter region.
    Ge YW; Ghosh C; Song W; Maloney B; Lahiri DK
    J Neurochem; 2004 Sep; 90(6):1432-44. PubMed ID: 15341527
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Functional characterization of amyloid beta precursor protein regulatory elements: rationale for the identification of genetic polymorphism.
    Lahiri DK
    Ann N Y Acad Sci; 2004 Dec; 1030():282-8. PubMed ID: 15659808
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Promoter polymorphisms which modulate APP expression may increase susceptibility to Alzheimer's disease.
    Lv H; Jia L; Jia J
    Neurobiol Aging; 2008 Feb; 29(2):194-202. PubMed ID: 17112637
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Overlapping binding sites of two different transcription factors in the promoter of the human gene for the Alzheimer amyloid precursor protein.
    Pollwein P
    Biochem Biophys Res Commun; 1993 Jan; 190(2):637-47. PubMed ID: 8427604
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Role of the APP promoter in Alzheimer's disease: cell type-specific expression of the beta-amyloid precursor protein.
    Lahiri DK; Ge YW
    Ann N Y Acad Sci; 2004 Dec; 1030():310-6. PubMed ID: 15659812
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The promoter activity of the gene encoding Alzheimer beta-amyloid precursor protein (APP) is regulated by two blocks of upstream sequences.
    Lahiri DK; Robakis NK
    Brain Res Mol Brain Res; 1991 Feb; 9(3):253-7. PubMed ID: 1851527
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Polymorphisms in the promoter of the human APP gene: functional evaluation and allele frequencies in Alzheimer disease.
    Athan ES; Lee JH; Arriaga A; Mayeux RP; Tycko B
    Arch Neurol; 2002 Nov; 59(11):1793-9. PubMed ID: 12433268
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Protein-DNA interactions in the promoter region of the amyloid precursor protein (APP) gene in human neocortex.
    Lukiw WJ; Rogaev EI; Wong L; Vaula G; McLachlan DR; St George Hyslop P
    Brain Res Mol Brain Res; 1994 Mar; 22(1-4):121-31. PubMed ID: 8015372
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A direct role for protein kinase C and the transcription factor Jun/AP-1 in the regulation of the Alzheimer's beta-amyloid precursor protein gene.
    Trejo J; Massamiri T; Deng T; Dewji NN; Bayney RM; Brown JH
    J Biol Chem; 1994 Aug; 269(34):21682-90. PubMed ID: 8063812
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of promoter activity of the APP gene by cytokines and growth factors: implications in Alzheimer's disease.
    Ge YW; Lahiri DK
    Ann N Y Acad Sci; 2002 Nov; 973():463-7. PubMed ID: 12485912
    [TBL] [Abstract][Full Text] [Related]  

  • 15. No evidence that common allelic variation in the Amyloid Precursor Protein (APP) gene confers susceptibility to Alzheimer's disease.
    Liddell MB; Bayer AJ; Owen MJ
    Hum Mol Genet; 1995 May; 4(5):853-8. PubMed ID: 7633445
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Amyloid protein-mediated differential DNA methylation status regulates gene expression in Alzheimer's disease model cell line.
    Sung HY; Choi EN; Ahn Jo S; Oh S; Ahn JH
    Biochem Biophys Res Commun; 2011 Nov; 414(4):700-5. PubMed ID: 22001921
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sp1 and Smad transcription factors co-operate to mediate TGF-beta-dependent activation of amyloid-beta precursor protein gene transcription.
    Docagne F; Gabriel C; Lebeurrier N; Lesné S; Hommet Y; Plawinski L; Mackenzie ET; Vivien D
    Biochem J; 2004 Oct; 383(Pt 2):393-9. PubMed ID: 15242331
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of common and rare APP DNA sequence variants in Alzheimer disease.
    Hooli BV; Mohapatra G; Mattheisen M; Parrado AR; Roehr JT; Shen Y; Gusella JF; Moir R; Saunders AJ; Lange C; Tanzi RE; Bertram L
    Neurology; 2012 Apr; 78(16):1250-7. PubMed ID: 22491860
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Screening for mutations in the open reading frame and promoter of the beta-amyloid precursor protein gene in familial Alzheimer's disease: identification of a further family with APP717 Val-->Ile.
    Fidani L; Rooke K; Chartier-Harlin MC; Hughes D; Tanzi R; Mullan M; Roques P; Rossor M; Hardy J; Goate A
    Hum Mol Genet; 1992 Jun; 1(3):165-8. PubMed ID: 1303172
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulation and expression of the Alzheimer's beta/A4 amyloid protein precursor in health, disease, and Down's syndrome.
    Beyreuther K; Pollwein P; Multhaup G; Mönning U; König G; Dyrks T; Schubert W; Masters CL
    Ann N Y Acad Sci; 1993 Sep; 695():91-102. PubMed ID: 8239320
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.