These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

238 related articles for article (PubMed ID: 16686428)

  • 1. Regulation of HIF: asparaginyl hydroxylation.
    Peet D; Linke S
    Novartis Found Symp; 2006; 272():37-49; discussion 49-53, 131-40. PubMed ID: 16686428
    [TBL] [Abstract][Full Text] [Related]  

  • 2. HIF hydroxylation and cellular oxygen sensing.
    Metzen E; Ratcliffe PJ
    Biol Chem; 2004; 385(3-4):223-30. PubMed ID: 15134335
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hypoxia-inducible factor prolyl-hydroxylase: purification and assays of PHD2.
    Hewitson KS; Schofield CJ; Ratcliffe PJ
    Methods Enzymol; 2007; 435():25-42. PubMed ID: 17998047
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hypoxia-inducible factor asparaginyl hydroxylase (FIH-1) catalyses hydroxylation at the beta-carbon of asparagine-803.
    McNeill LA; Hewitson KS; Claridge TD; Seibel JF; Horsfall LE; Schofield CJ
    Biochem J; 2002 Nov; 367(Pt 3):571-5. PubMed ID: 12215170
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of ankyrin repeat-containing proteins as substrates of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible transcription factor.
    Linke S; Hampton-Smith RJ; Peet DJ
    Methods Enzymol; 2007; 435():61-85. PubMed ID: 17998049
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regulation of HIF: prolyl hydroxylases.
    Stolze IP; Mole DR; Ratcliffe PJ
    Novartis Found Symp; 2006; 272():15-25; discussion 25-36. PubMed ID: 16686427
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Biochemical characterization of human HIF hydroxylases using HIF protein substrates that contain all three hydroxylation sites.
    Pappalardi MB; McNulty DE; Martin JD; Fisher KE; Jiang Y; Burns MC; Zhao H; Ho T; Sweitzer S; Schwartz B; Annan RS; Copeland RA; Tummino PJ; Luo L
    Biochem J; 2011 Jun; 436(2):363-9. PubMed ID: 21410436
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Substrate requirements of the oxygen-sensing asparaginyl hydroxylase factor-inhibiting hypoxia-inducible factor.
    Linke S; Stojkoski C; Kewley RJ; Booker GW; Whitelaw ML; Peet DJ
    J Biol Chem; 2004 Apr; 279(14):14391-7. PubMed ID: 14734545
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Expression of prolyl-hydroxylases PHD-1, 2 and 3 and of the asparagine hydroxylase FIH in non-small cell lung cancer relates to an activated HIF pathway.
    Giatromanolaki A; Koukourakis MI; Pezzella F; Turley H; Sivridis E; Bouros D; Bougioukas G; Harris AL; Gatter KC
    Cancer Lett; 2008 Apr; 262(1):87-93. PubMed ID: 18187257
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family.
    Hewitson KS; McNeill LA; Riordan MV; Tian YM; Bullock AN; Welford RW; Elkins JM; Oldham NJ; Bhattacharya S; Gleadle JM; Ratcliffe PJ; Pugh CW; Schofield CJ
    J Biol Chem; 2002 Jul; 277(29):26351-5. PubMed ID: 12042299
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of the Oxygen-Sensing Asparaginyl Hydroxylase Factor Inhibiting Hypoxia-Inducible Factor: A Potential Hypoxia Response Modulating Strategy.
    Wu Y; Li Z; McDonough MA; Schofield CJ; Zhang X
    J Med Chem; 2021 Jun; 64(11):7189-7209. PubMed ID: 34029087
    [TBL] [Abstract][Full Text] [Related]  

  • 12. MYPT1, the targeting subunit of smooth-muscle myosin phosphatase, is a substrate for the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH).
    Webb JD; Murányi A; Pugh CW; Ratcliffe PJ; Coleman ML
    Biochem J; 2009 May; 420(2):327-33. PubMed ID: 19245366
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases.
    Koivunen P; Hirsilä M; Günzler V; Kivirikko KI; Myllyharju J
    J Biol Chem; 2004 Mar; 279(11):9899-904. PubMed ID: 14701857
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Signalling cross talk of the HIF system: involvement of the FIH protein.
    Coleman ML; Ratcliffe PJ
    Curr Pharm Des; 2009; 15(33):3904-7. PubMed ID: 19671041
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Protein Hydroxylation by Hypoxia-Inducible Factor (HIF) Hydroxylases: Unique or Ubiquitous?
    Strowitzki MJ; Cummins EP; Taylor CT
    Cells; 2019 Apr; 8(5):. PubMed ID: 31035491
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hinokitiol activates the hypoxia-inducible factor (HIF) pathway through inhibition of HIF hydroxylases.
    Lee MJ; Kim JW; Yang EG
    Biochem Biophys Res Commun; 2010 May; 396(2):370-5. PubMed ID: 20416277
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differences in hydroxylation and binding of Notch and HIF-1alpha demonstrate substrate selectivity for factor inhibiting HIF-1 (FIH-1).
    Wilkins SE; Hyvärinen J; Chicher J; Gorman JJ; Peet DJ; Bilton RL; Koivunen P
    Int J Biochem Cell Biol; 2009 Jul; 41(7):1563-71. PubMed ID: 19401150
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cellular oxygen sensing need in CNS function: physiological and pathological implications.
    Acker T; Acker H
    J Exp Biol; 2004 Aug; 207(Pt 18):3171-88. PubMed ID: 15299039
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ferritin heavy chain controls the HIF-driven hypoxic response by activating the asparaginyl hydroxylase FIH.
    Jin P; Kang J; Lee MK; Park JW
    Biochem Biophys Res Commun; 2018 May; 499(3):475-481. PubMed ID: 29580991
    [TBL] [Abstract][Full Text] [Related]  

  • 20. FIH-dependent asparaginyl hydroxylation of ankyrin repeat domain-containing proteins.
    Cockman ME; Webb JD; Ratcliffe PJ
    Ann N Y Acad Sci; 2009 Oct; 1177():9-18. PubMed ID: 19845602
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.