175 related articles for article (PubMed ID: 16690312)
1. Synthesis and structure-activity relationships of piperidine-based melanin-concentrating hormone receptor 1 antagonists.
Wu WL; Burnett DA; Spring R; Qiang L; Sasikumar TK; Domalski MS; Greenlee WJ; O'Neill K; Hawes BE
Bioorg Med Chem Lett; 2006 Jul; 16(14):3668-73. PubMed ID: 16690312
[TBL] [Abstract][Full Text] [Related]
2. Structure-activity relationships of a novel series of melanin-concentrating hormone (MCH) receptor antagonists.
Arienzo R; Clark DE; Cramp S; Daly S; Dyke HJ; Lockey P; Norman D; Roach AG; Stuttle K; Tomlinson M; Wong M; Wren SP
Bioorg Med Chem Lett; 2004 Aug; 14(15):4099-102. PubMed ID: 15225734
[TBL] [Abstract][Full Text] [Related]
3. Discovery of novel spiro-piperidine derivatives as highly potent and selective melanin-concentrating hormone 1 receptor antagonists.
Suzuki T; Moriya M; Sakamoto T; Suga T; Kishino H; Takahashi H; Ishikawa M; Nagai K; Imai Y; Sekino E; Ito M; Iwaasa H; Ishihara A; Tokita S; Kanatani A; Sato N; Fukami T
Bioorg Med Chem Lett; 2009 Jun; 19(11):3072-7. PubMed ID: 19403308
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and structure-activity relationships of retro bis-aminopyrrolidine urea (rAPU) derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1). Part 1.
Rowbottom MW; Vickers TD; Dyck B; Grey J; Tamiya J; Zhang M; Kiankarimi M; Wu D; Dwight W; Wade WS; Schwarz D; Heise CE; Madan A; Fisher A; Petroski R; Goodfellow VS
Bioorg Med Chem Lett; 2006 Sep; 16(17):4450-7. PubMed ID: 16814542
[TBL] [Abstract][Full Text] [Related]
5. Solid-phase synthesis and structure-activity relationships of novel biarylethers as melanin-concentrating hormone receptor-1 antagonists.
Ma V; Bannon AW; Baumgartner J; Hale C; Hsieh F; Hulme C; Rorrer K; Salon J; van Staden C; Tempest P
Bioorg Med Chem Lett; 2006 Oct; 16(19):5066-72. PubMed ID: 16887348
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and structure-activity relationships of spirohydantoin-derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1).
Rowbottom MW; Vickers TD; Tamiya J; Zhang M; Dyck B; Grey J; Schwarz D; Heise CE; Hedrick M; Wen J; Tang H; Wang H; Fisher A; Aparicio A; Saunders J; Goodfellow VS
Bioorg Med Chem Lett; 2007 Apr; 17(8):2171-8. PubMed ID: 17350839
[TBL] [Abstract][Full Text] [Related]
7. Discovery of melanin-concentrating hormone receptor R1 antagonists using high-throughput synthesis.
Su J; McKittrick BA; Tang H; Czarniecki M; Greenlee WJ; Hawes BE; O'Neill K
Bioorg Med Chem; 2005 Mar; 13(5):1829-36. PubMed ID: 15698800
[TBL] [Abstract][Full Text] [Related]
8. Discovery of 4-(dimethylamino)quinazolines as potent and selective antagonists for the melanin-concentrating hormone receptor 1.
Kanuma K; Omodera K; Nishiguchi M; Funakoshi T; Chaki S; Semple G; Tran TA; Kramer B; Hsu D; Casper M; Thomsen B; Beeley N; Sekiguchi Y
Bioorg Med Chem Lett; 2005 May; 15(10):2565-9. PubMed ID: 15863317
[TBL] [Abstract][Full Text] [Related]
9. Design and synthesis of orally efficacious benzimidazoles as melanin-concentrating hormone receptor 1 antagonists.
Wu WL; Burnett DA; Caplen MA; Domalski MS; Bennett C; Greenlee WJ; Hawes BE; O'Neill K; Weig B; Weston D; Spar B; Kowalski T
Bioorg Med Chem Lett; 2006 Jul; 16(14):3674-8. PubMed ID: 16690315
[TBL] [Abstract][Full Text] [Related]
10. 4-Acylamino-and 4-ureidobenzamides as melanin-concentrating hormone (MCH) receptor 1 antagonists.
Receveur JM; Bjurling E; Ulven T; Little PB; Nørregaard PK; Högberg T
Bioorg Med Chem Lett; 2004 Oct; 14(20):5075-80. PubMed ID: 15380202
[TBL] [Abstract][Full Text] [Related]
11. Discovery and SAR of biaryl piperidine MCH1 receptor antagonists through solid-phase encoded combinatorial synthesis.
Guo T; Shao Y; Qian G; Rokosz LL; Stauffer TM; Hunter RC; Babu SD; Gu H; Hobbs DW
Bioorg Med Chem Lett; 2005 Aug; 15(16):3696-700. PubMed ID: 15978811
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and biological evaluation of phenyl piperidine derivatives as CCR2 antagonists.
Xia M; Hou C; Pollack S; Brackley J; DeMong D; Pan M; Singer M; Matheis M; Olini G; Cavender D; Wachter M
Bioorg Med Chem Lett; 2007 Nov; 17(21):5964-8. PubMed ID: 17869105
[TBL] [Abstract][Full Text] [Related]
13. The discovery and optimization of pyrimidinone-containing MCH R1 antagonists.
Hertzog DL; Al-Barazanji KA; Bigham EC; Bishop MJ; Britt CS; Carlton DL; Cooper JP; Daniels AJ; Garrido DM; Goetz AS; Grizzle MK; Guo YC; Handlon AL; Ignar DM; Morgan RO; Peat AJ; Tavares FX; Zhou H
Bioorg Med Chem Lett; 2006 Sep; 16(18):4723-7. PubMed ID: 16870432
[TBL] [Abstract][Full Text] [Related]
14. Discovery and characterization of aminopiperidinecoumarin melanin concentrating hormone receptor 1 antagonists.
Kym PR; Iyengar R; Souers AJ; Lynch JK; Judd AS; Gao J; Freeman J; Mulhern M; Zhao G; Vasudevan A; Wodka D; Blackburn C; Brown J; Che JL; Cullis C; Lai SJ; LaMarche MJ; Marsilje T; Roses J; Sells T; Geddes B; Govek E; Patane M; Fry D; Dayton BD; Brodjian S; Falls D; Brune M; Bush E; Shapiro R; Knourek-Segel V; Fey T; McDowell C; Reinhart GA; Preusser LC; Marsh K; Hernandez L; Sham HL; Collins CA
J Med Chem; 2005 Sep; 48(19):5888-91. PubMed ID: 16161992
[TBL] [Abstract][Full Text] [Related]
15. Novel series of substituted biphenylmethyl urea derivatives as MCH-R1 antagonists for the treatment of obesity.
Galiano S; Ceras J; Cirauqui N; Pérez S; Juanenea L; Rivera G; Aldana I; Monge A
Bioorg Med Chem; 2007 Jun; 15(11):3896-911. PubMed ID: 17407817
[TBL] [Abstract][Full Text] [Related]
16. 2,4-Disubstituted piperidines as selective CC chemokine receptor 3 (CCR3) antagonists: synthesis and selectivity.
Watson PS; Jiang B; Harrison K; Asakawa N; Welch PK; Covington M; Stowell NC; Wadman EA; Davies P; Solomon KA; Newton RC; Trainor GL; Friedman SM; Decicco CP; Ko SS
Bioorg Med Chem Lett; 2006 Nov; 16(21):5695-9. PubMed ID: 16931001
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and SAR study of pyrrolo[3,4-b]pyridin-7(6H)-one derivatives as melanin concentrating hormone receptor 1 (MCH-R1) antagonists.
Lim CJ; Kim JY; Lee BH; Oh KS; Yi KY
Bioorg Med Chem Lett; 2013 Mar; 23(6):1736-9. PubMed ID: 23411080
[TBL] [Abstract][Full Text] [Related]
18. The effects of stressful stimuli and hypothalamic-pituitary-adrenal axis activation are reversed by the melanin-concentrating hormone 1 receptor antagonist SNAP 94847 in rodents.
Smith DG; Hegde LG; Wolinsky TD; Miller S; Papp M; Ping X; Edwards T; Gerald CP; Craig DA
Behav Brain Res; 2009 Feb; 197(2):284-91. PubMed ID: 18793675
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and structure-activity relationships of a new series of 2alpha-substituted trans-4,5-dimethyl-4-(3-hydroxyphenyl)piperidine as mu-selective opioid antagonists.
Le Bourdonnec B; Goodman AJ; Michaut M; Ye HF; Graczyk TM; Belanger S; DeHaven RN; Dolle RE
Bioorg Med Chem Lett; 2006 Feb; 16(4):864-8. PubMed ID: 16298525
[TBL] [Abstract][Full Text] [Related]
20. Design and synthesis of novel hydantoin-containing melanin-concentrating hormone receptor antagonists.
Balavoine F; Malabre P; Alleaume T; Rey A; Cherfils V; Jeanneton O; Seigneurin-Venin S; Revah F
Bioorg Med Chem Lett; 2007 Jul; 17(13):3754-9. PubMed ID: 17448659
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
