BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 16690614)

  • 1. Characterization of the tandem GAF domain of human phosphodiesterase 5 using a cyanobacterial adenylyl cyclase as a reporter enzyme.
    Bruder S; Schultz A; Schultz JE
    J Biol Chem; 2006 Jul; 281(29):19969-76. PubMed ID: 16690614
    [TBL] [Abstract][Full Text] [Related]  

  • 2. cAMP is a ligand for the tandem GAF domain of human phosphodiesterase 10 and cGMP for the tandem GAF domain of phosphodiesterase 11.
    Gross-Langenhoff M; Hofbauer K; Weber J; Schultz A; Schultz JE
    J Biol Chem; 2006 Feb; 281(5):2841-6. PubMed ID: 16330539
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural and biochemical aspects of tandem GAF domains.
    Schultz JE
    Handb Exp Pharmacol; 2009; (191):93-109. PubMed ID: 19089327
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Trypanosome cyclic nucleotide phosphodiesterase 2B binds cAMP through its GAF-A domain.
    Laxman S; Rascón A; Beavo JA
    J Biol Chem; 2005 Feb; 280(5):3771-9. PubMed ID: 15563461
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Intramolecular signaling in tandem-GAF domains from PDE5 and PDE10 studied with a cyanobacterial adenylyl cyclase reporter.
    Banjac A; Zimmermann MO; Boeckler FM; Kurz U; Schultz A; Schultz JE
    Cell Signal; 2012 Mar; 24(3):629-34. PubMed ID: 22080917
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The cyanobacterial tandem GAF domains from the cyaB2 adenylyl cyclase signal via both cAMP-binding sites.
    Bruder S; Linder JU; Martinez SE; Zheng N; Beavo JA; Schultz JE
    Proc Natl Acad Sci U S A; 2005 Feb; 102(8):3088-92. PubMed ID: 15708972
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A 46-amino acid segment in phosphodiesterase-5 GAF-B domain provides for high vardenafil potency over sildenafil and tadalafil and is involved in phosphodiesterase-5 dimerization.
    Blount MA; Zoraghi R; Ke H; Bessay EP; Corbin JD; Francis SH
    Mol Pharmacol; 2006 Nov; 70(5):1822-31. PubMed ID: 16926278
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural and functional features in human PDE5A1 regulatory domain that provide for allosteric cGMP binding, dimerization, and regulation.
    Zoraghi R; Bessay EP; Corbin JD; Francis SH
    J Biol Chem; 2005 Mar; 280(12):12051-63. PubMed ID: 15677448
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Changes in purine specificity in tandem GAF chimeras from cyanobacterial cyaB1 adenylate cyclase and rat phosphodiesterase 2.
    Linder JU; Bruder S; Schultz A; Schultz JE
    FEBS J; 2007 Mar; 274(6):1514-23. PubMed ID: 17302738
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The properties of phosphodiesterase 11A4 GAF domains are regulated by modifications in its N-terminal domain.
    Gross-Langenhoff M; Stenzl A; Altenberend F; Schultz A; Schultz JE
    FEBS J; 2008 Apr; 275(8):1643-50. PubMed ID: 18312413
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Binding of cyclic nucleotides to phosphodiesterase 10A and 11A GAF domains does not stimulate catalytic activity.
    Matthiesen K; Nielsen J
    Biochem J; 2009 Oct; 423(3):401-9. PubMed ID: 19689430
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Crystal structure of the tandem GAF domains from a cyanobacterial adenylyl cyclase: modes of ligand binding and dimerization.
    Martinez SE; Bruder S; Schultz A; Zheng N; Schultz JE; Beavo JA; Linder JU
    Proc Natl Acad Sci U S A; 2005 Feb; 102(8):3082-7. PubMed ID: 15708973
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A GAF-domain-regulated adenylyl cyclase from Anabaena is a self-activating cAMP switch.
    Kanacher T; Schultz A; Linder JU; Schultz JE
    EMBO J; 2002 Jul; 21(14):3672-80. PubMed ID: 12110580
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Binding of cGMP to GAF domains in amphibian rod photoreceptor cGMP phosphodiesterase (PDE). Identification of GAF domains in PDE alphabeta subunits and distinct domains in the PDE gamma subunit involved in stimulation of cGMP binding to GAF domains.
    Yamazaki M; Li N; Bondarenko VA; Yamazaki RK; Baehr W; Yamazaki A
    J Biol Chem; 2002 Oct; 277(43):40675-86. PubMed ID: 12177054
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure of the GAF domain, a ubiquitous signaling motif and a new class of cyclic GMP receptor.
    Ho YS; Burden LM; Hurley JH
    EMBO J; 2000 Oct; 19(20):5288-99. PubMed ID: 11032796
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Functional chimeras of the phosphodiesterase 5 and 10 tandem GAF domains.
    Hofbauer K; Schultz A; Schultz JE
    J Biol Chem; 2008 Sep; 283(37):25164-25170. PubMed ID: 18635550
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cyclic guanosine 5'-monophosphate binding to regulatory GAF domains of photoreceptor phosphodiesterase.
    Cote RH
    Methods Mol Biol; 2005; 307():141-54. PubMed ID: 15988061
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Crystal structure of the GAF-B domain from human phosphodiesterase 10A complexed with its ligand, cAMP.
    Handa N; Mizohata E; Kishishita S; Toyama M; Morita S; Uchikubo-Kamo T; Akasaka R; Omori K; Kotera J; Terada T; Shirouzu M; Yokoyama S
    J Biol Chem; 2008 Jul; 283(28):19657-64. PubMed ID: 18477562
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The GAF-tandem domain of phosphodiesterase 5 as a potential drug target.
    Schultz JE; Dunkern T; Gawlitta-Gorka E; Sorg G
    Handb Exp Pharmacol; 2011; (204):151-66. PubMed ID: 21695639
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Isolation and characterization of two novel phosphodiesterase PDE11A variants showing unique structure and tissue-specific expression.
    Yuasa K; Kotera J; Fujishige K; Michibata H; Sasaki T; Omori K
    J Biol Chem; 2000 Oct; 275(40):31469-79. PubMed ID: 10906126
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.