183 related articles for article (PubMed ID: 16696853)
21. Induction of vascular GTP-cyclohydrolase I and endogenous tetrahydrobiopterin synthesis protect against inflammation-induced endothelial dysfunction in human atherosclerosis.
Antoniades C; Cunnington C; Antonopoulos A; Neville M; Margaritis M; Demosthenous M; Bendall J; Hale A; Cerrato R; Tousoulis D; Bakogiannis C; Marinou K; Toutouza M; Vlachopoulos C; Leeson P; Stefanadis C; Karpe F; Channon KM
Circulation; 2011 Oct; 124(17):1860-70. PubMed ID: 21969008
[TBL] [Abstract][Full Text] [Related]
22. Roles for endothelial cell and macrophage Gch1 and tetrahydrobiopterin in atherosclerosis progression.
Douglas G; Hale AB; Patel J; Chuaiphichai S; Al Haj Zen A; Rashbrook VS; Trelfa L; Crabtree MJ; McNeill E; Channon KM
Cardiovasc Res; 2018 Aug; 114(10):1385-1399. PubMed ID: 29596571
[TBL] [Abstract][Full Text] [Related]
23. A new use for a familiar fold: the X-ray crystal structure of GTP-bound GTP cyclohydrolase III from Methanocaldococcus jannaschii reveals a two metal ion catalytic mechanism.
Morrison SD; Roberts SA; Zegeer AM; Montfort WR; Bandarian V
Biochemistry; 2008 Jan; 47(1):230-42. PubMed ID: 18052207
[TBL] [Abstract][Full Text] [Related]
24. Mast cell tetrahydrobiopterin contributes to itch in mice.
Zschiebsch K; Fischer C; Wilken-Schmitz A; Geisslinger G; Channon K; Watschinger K; Tegeder I
J Cell Mol Med; 2019 Feb; 23(2):985-1000. PubMed ID: 30450838
[TBL] [Abstract][Full Text] [Related]
25. Atomic structure of GTP cyclohydrolase I.
Nar H; Huber R; Meining W; Schmid C; Weinkauf S; Bacher A
Structure; 1995 May; 3(5):459-66. PubMed ID: 7663943
[TBL] [Abstract][Full Text] [Related]
26. Characterization of cerebral microvasculature in transgenic mice with endothelium targeted over-expression of GTP-cyclohydrolase I.
Santhanam AV; d'Uscio LV; Katusic ZS
Brain Res; 2015 Nov; 1625():198-205. PubMed ID: 26343845
[TBL] [Abstract][Full Text] [Related]
27. The protein partners of GTP cyclohydrolase I in rat organs.
Du J; Teng RJ; Lawrence M; Guan T; Xu H; Ge Y; Shi Y
PLoS One; 2012; 7(3):e33991. PubMed ID: 22479495
[TBL] [Abstract][Full Text] [Related]
28. Augmented BH4 by gene transfer restores nitric oxide synthase function in hyperglycemic human endothelial cells.
Cai S; Khoo J; Channon KM
Cardiovasc Res; 2005 Mar; 65(4):823-31. PubMed ID: 15721862
[TBL] [Abstract][Full Text] [Related]
29. Over-expression of GTP-cyclohydrolase 1 feedback regulatory protein attenuates LPS and cytokine-stimulated nitric oxide production.
Nandi M; Kelly P; Vallance P; Leiper J
Vasc Med; 2008 Feb; 13(1):29-36. PubMed ID: 18372436
[TBL] [Abstract][Full Text] [Related]
30. GTP cyclohydrolase I feedback regulatory protein-dependent and -independent inhibitors of GTP cyclohydrolase I.
Yoneyama T; Wilson LM; Hatakeyama K
Arch Biochem Biophys; 2001 Apr; 388(1):67-73. PubMed ID: 11361142
[TBL] [Abstract][Full Text] [Related]
31. Preserving mitochondrial function prevents the proteasomal degradation of GTP cyclohydrolase I.
Sharma S; Sun X; Kumar S; Rafikov R; Aramburo A; Kalkan G; Tian J; Rehmani I; Kallarackal S; Fineman JR; Black SM
Free Radic Biol Med; 2012 Jul; 53(2):216-29. PubMed ID: 22583703
[TBL] [Abstract][Full Text] [Related]
32. Inhibition of GTP cyclohydrolase attenuates tumor growth by reducing angiogenesis and M2-like polarization of tumor associated macrophages.
Pickert G; Lim HY; Weigert A; Häussler A; Myrczek T; Waldner M; Labocha S; Ferreirós N; Geisslinger G; Lötsch J; Becker C; Brüne B; Tegeder I
Int J Cancer; 2013 Feb; 132(3):591-604. PubMed ID: 22753274
[TBL] [Abstract][Full Text] [Related]
33. Mechanism of reversal of high glucose-induced endothelial nitric oxide synthase uncoupling by tanshinone IIA in human endothelial cell line EA.hy926.
Zhou ZW; Xie XL; Zhou SF; Li CG
Eur J Pharmacol; 2012 Dec; 697(1-3):97-105. PubMed ID: 23063542
[TBL] [Abstract][Full Text] [Related]
34. GTP cyclohydrolase I gene transfer augments intracellular tetrahydrobiopterin in human endothelial cells: effects on nitric oxide synthase activity, protein levels and dimerisation.
Cai S; Alp NJ; McDonald D; Smith I; Kay J; Canevari L; Heales S; Channon KM
Cardiovasc Res; 2002 Sep; 55(4):838-49. PubMed ID: 12176133
[TBL] [Abstract][Full Text] [Related]
35. The neurobiology of tetrahydrobiopterin biosynthesis: a model for regulation of GTP cyclohydrolase I gene transcription within nigrostriatal dopamine neurons.
Kapatos G
IUBMB Life; 2013 Apr; 65(4):323-33. PubMed ID: 23457032
[TBL] [Abstract][Full Text] [Related]
36. l-Phenylalanine Restores Vascular Function in Spontaneously Hypertensive Rats Through Activation of the GCH1-GFRP Complex.
Heikal L; Starr A; Hussein D; Prieto-Lloret J; Aaronson P; Dailey LA; Nandi M
JACC Basic Transl Sci; 2018 Jun; 3(3):366-377. PubMed ID: 29963647
[TBL] [Abstract][Full Text] [Related]
37. Allosteric characteristics of GTP cyclohydrolase I from Escherichia coli.
Schoedon G; Redweik U; Frank G; Cotton RG; Blau N
Eur J Biochem; 1992 Dec; 210(2):561-8. PubMed ID: 1459137
[TBL] [Abstract][Full Text] [Related]
38. Cigarette smoke constituents cause endothelial nitric oxide synthase dysfunction and uncoupling due to depletion of tetrahydrobiopterin with degradation of GTP cyclohydrolase.
Abdelghany TM; Ismail RS; Mansoor FA; Zweier JR; Lowe F; Zweier JL
Nitric Oxide; 2018 Jun; 76():113-121. PubMed ID: 29524646
[TBL] [Abstract][Full Text] [Related]
39. Crystal structure of the stimulatory complex of GTP cyclohydrolase I and its feedback regulatory protein GFRP.
Maita N; Okada K; Hatakeyama K; Hakoshima T
Proc Natl Acad Sci U S A; 2002 Feb; 99(3):1212-7. PubMed ID: 11818540
[TBL] [Abstract][Full Text] [Related]
40. Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery.
Meyer P; Prodromou C; Liao C; Hu B; Roe SM; Vaughan CK; Vlasic I; Panaretou B; Piper PW; Pearl LH
EMBO J; 2004 Mar; 23(6):1402-10. PubMed ID: 15039704
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]