1018 related articles for article (PubMed ID: 16697956)
1. Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members.
Certo M; Del Gaizo Moore V; Nishino M; Wei G; Korsmeyer S; Armstrong SA; Letai A
Cancer Cell; 2006 May; 9(5):351-65. PubMed ID: 16697956
[TBL] [Abstract][Full Text] [Related]
2. Differences in the mechanisms of proapoptotic BH3 proteins binding to Bcl-XL and Bcl-2 quantified in live MCF-7 cells.
Aranovich A; Liu Q; Collins T; Geng F; Dixit S; Leber B; Andrews DW
Mol Cell; 2012 Mar; 45(6):754-63. PubMed ID: 22464442
[TBL] [Abstract][Full Text] [Related]
3. BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly.
Kuwana T; Bouchier-Hayes L; Chipuk JE; Bonzon C; Sullivan BA; Green DR; Newmeyer DD
Mol Cell; 2005 Feb; 17(4):525-35. PubMed ID: 15721256
[TBL] [Abstract][Full Text] [Related]
4. B cell lymphoma-2 (BCL-2) homology domain 3 (BH3) mimetics demonstrate differential activities dependent upon the functional repertoire of pro- and anti-apoptotic BCL-2 family proteins.
Renault TT; Elkholi R; Bharti A; Chipuk JE
J Biol Chem; 2014 Sep; 289(38):26481-26491. PubMed ID: 25096574
[TBL] [Abstract][Full Text] [Related]
5. Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737.
Del Gaizo Moore V; Brown JR; Certo M; Love TM; Novina CD; Letai A
J Clin Invest; 2007 Jan; 117(1):112-21. PubMed ID: 17200714
[TBL] [Abstract][Full Text] [Related]
6. Interactions of pro-apoptotic BH3 proteins with anti-apoptotic Bcl-2 family proteins measured in live MCF-7 cells using FLIM FRET.
Liu Q; Leber B; Andrews DW
Cell Cycle; 2012 Oct; 11(19):3536-42. PubMed ID: 22895112
[TBL] [Abstract][Full Text] [Related]
7. Targeting ERK1/2-bim signaling cascades by BH3-mimetic ABT-737 as an alternative therapeutic strategy for oral cancer.
Shin JA; Kim LH; Lee SJ; Jeong JH; Jung JY; Lee HN; Hong IS; Cho SD
Oncotarget; 2015 Nov; 6(34):35667-83. PubMed ID: 26447615
[TBL] [Abstract][Full Text] [Related]
8. BCL-2 dependence and ABT-737 sensitivity in acute lymphoblastic leukemia.
Del Gaizo Moore V; Schlis KD; Sallan SE; Armstrong SA; Letai A
Blood; 2008 Feb; 111(4):2300-9. PubMed ID: 18056841
[TBL] [Abstract][Full Text] [Related]
9. BH3 profiling identifies three distinct classes of apoptotic blocks to predict response to ABT-737 and conventional chemotherapeutic agents.
Deng J; Carlson N; Takeyama K; Dal Cin P; Shipp M; Letai A
Cancer Cell; 2007 Aug; 12(2):171-85. PubMed ID: 17692808
[TBL] [Abstract][Full Text] [Related]
10. Acquired resistance to ABT-737 in lymphoma cells that up-regulate MCL-1 and BFL-1.
Yecies D; Carlson NE; Deng J; Letai A
Blood; 2010 Apr; 115(16):3304-13. PubMed ID: 20197552
[TBL] [Abstract][Full Text] [Related]
11. Bh3 induced conformational changes in Bcl-Xl revealed by crystal structure and comparative analysis.
Rajan S; Choi M; Baek K; Yoon HS
Proteins; 2015 Jul; 83(7):1262-72. PubMed ID: 25907960
[TBL] [Abstract][Full Text] [Related]
12. Nuclear magnetic resonance study of protein-protein interactions involving apoptosis regulator Diva (Boo) and the BH3 domain of proapoptotic Bcl-2 members.
Santiveri CM; Sborgi L; de Alba E
J Mol Recognit; 2012 Dec; 25(12):665-73. PubMed ID: 23192964
[TBL] [Abstract][Full Text] [Related]
13. Multiple BH3 mimetics antagonize antiapoptotic MCL1 protein by inducing the endoplasmic reticulum stress response and up-regulating BH3-only protein NOXA.
Albershardt TC; Salerni BL; Soderquist RS; Bates DJ; Pletnev AA; Kisselev AF; Eastman A
J Biol Chem; 2011 Jul; 286(28):24882-95. PubMed ID: 21628457
[TBL] [Abstract][Full Text] [Related]
14. BIM and tBID are not mechanistically equivalent when assisting BAX to permeabilize bilayer membranes.
Terrones O; Etxebarria A; Landajuela A; Landeta O; Antonsson B; Basañez G
J Biol Chem; 2008 Mar; 283(12):7790-803. PubMed ID: 18195012
[TBL] [Abstract][Full Text] [Related]
15. Identification of predictive factors of response to the BH3-mimetic molecule ABT-737: an ex vivo experiment in human serous ovarian carcinoma.
Lheureux S; N'Diaye M; Blanc-Fournier C; Dugué AE; Clarisse B; Dutoit S; Giffard F; Abeilard E; Briand M; Labiche A; Grellard JM; Crouet H; Martin S; Joly F; Poulain L
Int J Cancer; 2015 Mar; 136(5):E340-50. PubMed ID: 25066666
[TBL] [Abstract][Full Text] [Related]
16. Molecular determinants of Bim(BH3) peptide binding to pro-survival proteins.
Delgado-Soler L; Pinto M; Tanaka-Gil K; Rubio-Martinez J
J Chem Inf Model; 2012 Aug; 52(8):2107-18. PubMed ID: 22794663
[TBL] [Abstract][Full Text] [Related]
17. Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak.
Willis SN; Fletcher JI; Kaufmann T; van Delft MF; Chen L; Czabotar PE; Ierino H; Lee EF; Fairlie WD; Bouillet P; Strasser A; Kluck RM; Adams JM; Huang DC
Science; 2007 Feb; 315(5813):856-9. PubMed ID: 17289999
[TBL] [Abstract][Full Text] [Related]
18. The Bcl-2 homology domain 3 (BH3)-only proteins Bim and bid are functionally active and restrained by anti-apoptotic Bcl-2 family proteins in healthy liver.
Kodama T; Hikita H; Kawaguchi T; Saito Y; Tanaka S; Shigekawa M; Shimizu S; Li W; Miyagi T; Kanto T; Hiramatsu N; Tatsumi T; Takehara T
J Biol Chem; 2013 Oct; 288(42):30009-30018. PubMed ID: 23986435
[TBL] [Abstract][Full Text] [Related]
19. An interconnected hierarchical model of cell death regulation by the BCL-2 family.
Chen HC; Kanai M; Inoue-Yamauchi A; Tu HC; Huang Y; Ren D; Kim H; Takeda S; Reyna DE; Chan PM; Ganesan YT; Liao CP; Gavathiotis E; Hsieh JJ; Cheng EH
Nat Cell Biol; 2015 Oct; 17(10):1270-81. PubMed ID: 26344567
[TBL] [Abstract][Full Text] [Related]
20. BOD (Bcl-2-related ovarian death gene) is an ovarian BH3 domain-containing proapoptotic Bcl-2 protein capable of dimerization with diverse antiapoptotic Bcl-2 members.
Hsu SY; Lin P; Hsueh AJ
Mol Endocrinol; 1998 Sep; 12(9):1432-40. PubMed ID: 9731710
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]