BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

242 related articles for article (PubMed ID: 16702947)

  • 1. c-Abl phosphorylates Hdm2 at tyrosine 276 in response to DNA damage and regulates interaction with ARF.
    Dias SS; Milne DM; Meek DW
    Oncogene; 2006 Oct; 25(50):6666-71. PubMed ID: 16702947
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage.
    Pereg Y; Shkedy D; de Graaf P; Meulmeester E; Edelson-Averbukh M; Salek M; Biton S; Teunisse AF; Lehmann WD; Jochemsen AG; Shiloh Y
    Proc Natl Acad Sci U S A; 2005 Apr; 102(14):5056-61. PubMed ID: 15788536
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tyrosine phosphorylation of Mdm2 by c-Abl: implications for p53 regulation.
    Goldberg Z; Vogt Sionov R; Berger M; Zwang Y; Perets R; Van Etten RA; Oren M; Taya Y; Haupt Y
    EMBO J; 2002 Jul; 21(14):3715-27. PubMed ID: 12110584
    [TBL] [Abstract][Full Text] [Related]  

  • 4. hnRNP K: an HDM2 target and transcriptional coactivator of p53 in response to DNA damage.
    Moumen A; Masterson P; O'Connor MJ; Jackson SP
    Cell; 2005 Dec; 123(6):1065-78. PubMed ID: 16360036
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage.
    Chen L; Gilkes DM; Pan Y; Lane WS; Chen J
    EMBO J; 2005 Oct; 24(19):3411-22. PubMed ID: 16163388
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ATM complexes with HDM2 and promotes its rapid phosphorylation in a p53-independent manner in normal and tumor human cells exposed to ionizing radiation.
    de Toledo SM; Azzam EI; Dahlberg WK; Gooding TB; Little JB
    Oncogene; 2000 Dec; 19(54):6185-93. PubMed ID: 11175332
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A positive role for c-Abl in Atm and Atr activation in DNA damage response.
    Wang X; Zeng L; Wang J; Chau JF; Lai KP; Jia D; Poonepalli A; Hande MP; Liu H; He G; He L; Li B
    Cell Death Differ; 2011 Jan; 18(1):5-15. PubMed ID: 20798688
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Indole-3-carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cells.
    Brew CT; Aronchik I; Hsu JC; Sheen JH; Dickson RB; Bjeldanes LF; Firestone GL
    Int J Cancer; 2006 Feb; 118(4):857-68. PubMed ID: 16152627
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phosphorylation of the Mdm2 oncoprotein by the c-Abl tyrosine kinase regulates p53 tumor suppression and the radiosensitivity of mice.
    Carr MI; Roderick JE; Zhang H; Woda BA; Kelliher MA; Jones SN
    Proc Natl Acad Sci U S A; 2016 Dec; 113(52):15024-15029. PubMed ID: 27956626
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage.
    Maya R; Balass M; Kim ST; Shkedy D; Leal JF; Shifman O; Moas M; Buschmann T; Ronai Z; Shiloh Y; Kastan MB; Katzir E; Oren M
    Genes Dev; 2001 May; 15(9):1067-77. PubMed ID: 11331603
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mechanism of p53 stabilization by ATM after DNA damage.
    Cheng Q; Chen J
    Cell Cycle; 2010 Feb; 9(3):472-8. PubMed ID: 20081365
    [TBL] [Abstract][Full Text] [Related]  

  • 12. c-Abl phosphorylates Hdmx and regulates its interaction with p53.
    Zuckerman V; Lenos K; Popowicz GM; Silberman I; Grossman T; Marine JC; Holak TA; Jochemsen AG; Haupt Y
    J Biol Chem; 2009 Feb; 284(6):4031-9. PubMed ID: 19075013
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential roles of ATM- and Chk2-mediated phosphorylations of Hdmx in response to DNA damage.
    Pereg Y; Lam S; Teunisse A; Biton S; Meulmeester E; Mittelman L; Buscemi G; Okamoto K; Taya Y; Shiloh Y; Jochemsen AG
    Mol Cell Biol; 2006 Sep; 26(18):6819-31. PubMed ID: 16943424
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phosphorylation of Daxx by ATM contributes to DNA damage-induced p53 activation.
    Tang J; Agrawal T; Cheng Q; Qu L; Brewer MD; Chen J; Yang X
    PLoS One; 2013; 8(2):e55813. PubMed ID: 23405218
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Determination of cell fate by c-Abl activation in the response to DNA damage.
    Kharbanda S; Yuan ZM; Weichselbaum R; Kufe D
    Oncogene; 1998 Dec; 17(25):3309-18. PubMed ID: 9916993
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Effect of papillary thyroid carcinoma related gene PTC1 on subcellular localization and function of ATM cell].
    Tie Y; Mao JP; Liu B; Song Y; Dong Y; Sun ZX
    Ai Zheng; 2004 May; 23(5):487-92. PubMed ID: 15142440
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation.
    Baskaran R; Wood LD; Whitaker LL; Canman CE; Morgan SE; Xu Y; Barlow C; Baltimore D; Wynshaw-Boris A; Kastan MB; Wang JY
    Nature; 1997 May; 387(6632):516-9. PubMed ID: 9168116
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ATM-mediated phosphorylation activates the tumor-suppressive function of B56γ-PP2A.
    Shouse GP; Nobumori Y; Panowicz MJ; Liu X
    Oncogene; 2011 Sep; 30(35):3755-65. PubMed ID: 21460856
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ATM engages autodegradation of the E3 ubiquitin ligase COP1 after DNA damage.
    Dornan D; Shimizu H; Mah A; Dudhela T; Eby M; O'rourke K; Seshagiri S; Dixit VM
    Science; 2006 Aug; 313(5790):1122-6. PubMed ID: 16931761
    [TBL] [Abstract][Full Text] [Related]  

  • 20. p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage.
    Yuan ZM; Shioya H; Ishiko T; Sun X; Gu J; Huang YY; Lu H; Kharbanda S; Weichselbaum R; Kufe D
    Nature; 1999 Jun; 399(6738):814-7. PubMed ID: 10391251
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.