BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

503 related articles for article (PubMed ID: 1670962)

  • 1. Relationship between expression of P-glycoprotein and efficacy of trifluoperazine in multidrug-resistant cells.
    Ganapathi R; Kuo T; Teeter L; Grabowski D; Ford J
    Mol Pharmacol; 1991 Jan; 39(1):1-8. PubMed ID: 1670962
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Trifluoperazine modulation of resistance to the topoisomerase II inhibitor etoposide in doxorubicin resistant L1210 murine leukemia cells.
    Kamath N; Grabowski D; Ford J; Drake F; Kerrigan D; Pommier Y; Ganapathi R
    Cancer Commun; 1991 Feb; 3(2):37-44. PubMed ID: 1995027
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differential effect of the calmodulin inhibitor trifluoperazine on cellular accumulation, retention, and cytotoxicity of anthracyclines in doxorubicin (adriamycin)-resistant P388 mouse leukemia cells.
    Ganapathi R; Grabowski D; Rouse W; Riegler F
    Cancer Res; 1984 Nov; 44(11):5056-61. PubMed ID: 6488165
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Progressive resistance to doxorubicin in mouse leukemia L1210 cells with multidrug resistance phenotype: reductions in drug-induced topoisomerase II-mediated DNA cleavage.
    Ganapathi R; Grabowski D; Ford J; Heiss C; Kerrigan D; Pommier Y
    Cancer Commun; 1989; 1(4):217-24. PubMed ID: 2576973
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of four doxorubicin adapted human breast cancer cell lines with respect to chemotherapeutic drug sensitivity, drug resistance associated membrane proteins and glutathione transferases.
    de la Torre M; Hao XY; Larsson R; Nygren P; Tsuruo T; Mannervik B; Bergh J
    Anticancer Res; 1993; 13(5A):1425-30. PubMed ID: 7902062
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Differential effect of the calmodulin inhibitor trifluoperazine in modulating cellular accumulation, retention and cytotoxicity of doxorubicin in progressively doxorubicin-resistant L1210 mouse leukemia cells. Lack of correlation between cellular doxorubicin levels and expression of resistance.
    Ganapathi R; Grabowski D
    Biochem Pharmacol; 1988 Jan; 37(2):185-93. PubMed ID: 3342075
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Factors governing the modulation of vinca-alkaloid resistance in doxorubicin-resistant cells by the calmodulin inhibitor trifluoperazine.
    Ganapathi R; Grabowski D; Schmidt H
    Biochem Pharmacol; 1986 Feb; 35(4):673-8. PubMed ID: 3947398
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pharmacological and biological evidence for differing mechanisms of doxorubicin resistance in two human tumor cell lines.
    Slovak ML; Hoeltge GA; Dalton WS; Trent JM
    Cancer Res; 1988 May; 48(10):2793-7. PubMed ID: 2896069
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Induction of multidrug resistance in MOLT-4 cells by anticancer agents is closely related to increased expression of functional P-glycoprotein and MDR1 mRNA.
    Liu ZL; Onda K; Tanaka S; Toma T; Hirano T; Oka K
    Cancer Chemother Pharmacol; 2002 May; 49(5):391-7. PubMed ID: 11976833
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Combined treatment of P-gp-positive L1210/VCR cells by verapamil and all-trans retinoic acid induces down-regulation of P-glycoprotein expression and transport activity.
    Sulová Z; Macejová D; Seres M; Sedlák J; Brtko J; Breier A
    Toxicol In Vitro; 2008 Feb; 22(1):96-105. PubMed ID: 17920233
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Selective enhancement of vincristine cytotoxicity in multidrug-resistant tumor cells by dilantin (phenytoin).
    Ganapathi R; Hercbergs A; Grabowski D; Ford J
    Cancer Res; 1993 Jul; 53(14):3262-5. PubMed ID: 8100737
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Modulation in vitro and in vivo of cytotoxicity but not cellular levels of doxorubicin by the calmodulin inhibitor trifluoperazine is dependent on the level of resistance.
    Ganapathi R; Schmidt H; Grabowski D; Melia M; Ratliff N
    Br J Cancer; 1988 Sep; 58(3):335-40. PubMed ID: 3179186
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Time dependence of [3H]-vincristine accumulation by L1210 mouse leukemic cells. Effect of P-glycoprotein overexpression.
    Breier A; Stefanková Z; Barancík M; Tribulová N
    Gen Physiol Biophys; 1994 Aug; 13(4):287-98. PubMed ID: 7890145
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Overexpression of the multidrug resistance-associated protein (MRP) gene in vincristine but not doxorubicin-selected multidrug-resistant murine erythroleukemia cells.
    Slapak CA; Fracasso PM; Martell RL; Toppmeyer DL; Lecerf JM; Levy SB
    Cancer Res; 1994 Nov; 54(21):5607-13. PubMed ID: 7923205
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Calmodulin inhibitor trifluoperazine in combination with doxorubicin induces the selection of tumour cells with the multidrug resistant phenotype.
    Kamath N; Grabowski D; Ford J; Ganapathi R
    Br J Cancer; 1993 Jun; 67(6):1203-8. PubMed ID: 8099806
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Atypical multidrug resistance in a therapy-induced drug-resistant human leukemia cell line (LALW-2): resistance to Vinca alkaloids independent of P-glycoprotein.
    Haber M; Norris MD; Kavallaris M; Bell DR; Davey RA; White L; Stewart BW
    Cancer Res; 1989 Oct; 49(19):5281-7. PubMed ID: 2569932
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Role of differential drug uptake, efflux, and binding of etoposide in sensitive and resistant human tumor cell lines: implications for the mechanisms of drug resistance.
    Politi PM; Sinha BK
    Mol Pharmacol; 1989 Mar; 35(3):271-8. PubMed ID: 2564628
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Bcl-2 and mdr-1 gene expression during doxorubicin-induced apoptosis in murine leukemic P388 and P388/R84 cells.
    Ramachandran C; You W; Krishan A
    Anticancer Res; 1997; 17(5A):3369-76. PubMed ID: 9413174
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Direct interaction between verapamil and doxorubicin causes the lack of reversal effect of verapamil on P-glycoprotein mediated resistance to doxorubicin in vitro using L1210/VCR cells.
    Breier A; Drobná Z; Barancík M
    Neoplasma; 1998; 45(4):248-53. PubMed ID: 9890669
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular mechanisms of loss of beta 2-microglobulin expression in drug-resistant breast cancer sublines and its involvement in drug resistance.
    Ogretmen B; McCauley MD; Safa AR
    Biochemistry; 1998 Aug; 37(33):11679-91. PubMed ID: 9709006
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.