125 related articles for article (PubMed ID: 16711766)
1. A genetic-function-approximation-based QSAR model for the affinity of arylpiperazines toward alpha1 adrenoceptors.
Maccari L; Magnani M; Strappaghetti G; Corelli F; Botta M; Manetti F
J Chem Inf Model; 2006; 46(3):1466-78. PubMed ID: 16711766
[TBL] [Abstract][Full Text] [Related]
2. Alpha1-adrenoceptor antagonists. 6. Structural optimization of pyridazinone-arylpiperazines. Study of the influence on affinity and selectivity of cyclic substituents at the pyridazinone ring and alkoxy groups at the arylpiperazine moiety.
Betti L; Corelli F; Floridi M; Giannaccini G; Maccari L; Manetti F; Strappaghetti G; Botta M
J Med Chem; 2003 Jul; 46(16):3555-8. PubMed ID: 12877594
[TBL] [Abstract][Full Text] [Related]
3. Synthesis, pharmacological evaluation, and structure-activity relationship and quantitative structure-activity relationship studies on novel derivatives of 2,4-diamino-6,7-dimethoxyquinazoline alpha1-adrenoceptor antagonists.
Leonardi A; Motta G; Boi C; Testa R; Poggesi E; De Benedetti PG; Menziani MC
J Med Chem; 1999 Feb; 42(3):427-37. PubMed ID: 9986714
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and structure-activity relationships of a new model of arylpiperazines. 8. Computational simulation of ligand-receptor interaction of 5-HT(1A)R agonists with selectivity over alpha1-adrenoceptors.
López-Rodríguez ML; Morcillo MJ; Fernández E; Benhamú B; Tejada I; Ayala D; Viso A; Campillo M; Pardo L; Delgado M; Manzanares J; Fuentes JA
J Med Chem; 2005 Apr; 48(7):2548-58. PubMed ID: 15801844
[TBL] [Abstract][Full Text] [Related]
5. Synthesis of new piperazine-pyridazinone derivatives and their binding affinity toward alpha1-, alpha2-adrenergic and 5-HT1A serotoninergic receptors.
Betti L; Zanelli M; Giannaccini G; Manetti F; Schenone S; Strappaghetti G
Bioorg Med Chem; 2006 Apr; 14(8):2828-36. PubMed ID: 16376083
[TBL] [Abstract][Full Text] [Related]
6. Search for influence of spatial properties on affinity at α1-adrenoceptor subtypes for phenylpiperazine derivatives of phenytoin.
Handzlik J; Pertz HH; Görnemann T; Jähnichen S; Kieć-Kononowicz K
Bioorg Med Chem Lett; 2010 Oct; 20(20):6152-6. PubMed ID: 20813529
[TBL] [Abstract][Full Text] [Related]
7. Synthesis of 3-arylpiperazinylalkylpyrrolo[3,2-d]pyrimidine-2,4-dione derivatives as novel, potent, and selective alpha1-adrenoceptor ligands.
Patanè E; Pittalà V; Guerrera F; Salerno L; Romeo G; Siracusa MA; Russo F; Manetti F; Botta M; Mereghetti I; Cagnotto A; Mennini T
J Med Chem; 2005 Apr; 48(7):2420-31. PubMed ID: 15801833
[TBL] [Abstract][Full Text] [Related]
8. Pharmacophore-based design, synthesis, biological evaluation, and 3D-QSAR studies of aryl-piperazines as alpha(1)-adrenoceptor antagonists.
Li MY; Fang H; Xia L
Bioorg Med Chem Lett; 2005 Jul; 15(13):3216-9. PubMed ID: 15935663
[TBL] [Abstract][Full Text] [Related]
9. A rationale for the activity profile of arylpiperazinylthioalkyls as 5-HT1A-serotonin and alpha1-adrenergic receptor ligands.
Sharma BK; Sarbhai K; Singh P
Eur J Med Chem; 2010 May; 45(5):1927-34. PubMed ID: 20129717
[TBL] [Abstract][Full Text] [Related]
10. New 4-(4-methyl-phenyl)phthalazin-1(2H)-one derivatives and their effects on alpha1-receptors.
Strappaghetti G; Brodi C; Giannaccini G; Betti L
Bioorg Med Chem Lett; 2006 May; 16(10):2575-9. PubMed ID: 16545955
[TBL] [Abstract][Full Text] [Related]
11. Quantitative structure-activity relationship analysis of aryl alkanol piperazine derivatives with antidepressant activities.
Chen KX; Li ZG; Xie HY; Gao JR; Zou JW
Eur J Med Chem; 2009 Nov; 44(11):4367-75. PubMed ID: 19581024
[TBL] [Abstract][Full Text] [Related]
12. CoMFA methodology in structure-activity analysis of hexahydro- and octahydropyrido[1,2-c]pyrimidine derivatives based on affinity towards 5-HT1A, 5-HT2A and alpha1-adrenergic receptors.
Maciejewska D; Zołek T; Herold F
J Mol Graph Model; 2006 Nov; 25(3):353-62. PubMed ID: 16542863
[TBL] [Abstract][Full Text] [Related]
13. New pyrimido[5,4-b]indoles as ligands for alpha(1)-adrenoceptor subtypes.
Romeo G; Materia L; Manetti F; Cagnotto A; Mennini T; Nicoletti F; Botta M; Russo F; Minneman KP
J Med Chem; 2003 Jul; 46(14):2877-94. PubMed ID: 12825930
[TBL] [Abstract][Full Text] [Related]
14. Alpha(1)-adrenoceptor antagonists. 4. Pharmacophore-based design, synthesis, and biological evaluation of new imidazo-, benzimidazo-, and indoloarylpiperazine derivatives.
Betti L; Botta M; Corelli F; Floridi M; Giannaccini G; Maccari L; Manetti F; Strappaghetti G; Tafi A; Corsano S
J Med Chem; 2002 Aug; 45(17):3603-11. PubMed ID: 12166933
[TBL] [Abstract][Full Text] [Related]
15. New 1,2,3,9-tetrahydro-4H-carbazol-4-one derivatives: analogues of HEAT as ligands for the alpha1-adrenergic receptor subtypes.
Romeo G; Materia L; Pittalà V; Modica M; Salerno L; Siracusa M; Russo F; Minneman KP
Bioorg Med Chem; 2006 Aug; 14(15):5211-9. PubMed ID: 16647264
[TBL] [Abstract][Full Text] [Related]
16. Ligand-based pharmacophore model of N-Aryl and N-Heteroaryl piperazine alpha 1A-adrenoceptors antagonists using GALAHAD.
Zhao X; Yuan M; Huang B; Ji H; Zhu L
J Mol Graph Model; 2010 Sep; 29(2):126-36. PubMed ID: 20538497
[TBL] [Abstract][Full Text] [Related]
17. Structure-based 3D-QSAR studies on heteroarylpiperazine derivatives as 5-HT3 receptor antagonists.
Zhou YJ; Zhu LP; Tang Y; Ye DY
Eur J Med Chem; 2007 Jul; 42(7):977-84. PubMed ID: 17331624
[TBL] [Abstract][Full Text] [Related]
18. Design, synthesis, crystal structure, biological evaluation and molecular docking studies of carbazole-arylpiperazine derivatives.
Xu W; Huang J; Shao B; Xu X; Jiang R; Yuan M
Bioorg Med Chem; 2016 Nov; 24(21):5565-5572. PubMed ID: 27663545
[TBL] [Abstract][Full Text] [Related]
19. QSAR study for a novel series of ortho disubstituted phenoxy analogues of alpha1-adrenoceptor antagonist WB4101.
Pallavicini M; Fumagalli L; Gobbi M; Bolchi C; Colleoni S; Moroni B; Pedretti A; Rusconi C; Vistoli G; Valoti E
Eur J Med Chem; 2006 Sep; 41(9):1025-40. PubMed ID: 16737760
[TBL] [Abstract][Full Text] [Related]
20. QSAR study on the affinity of some arylpiperazines towards the 5-HT1A/alpha1-adrenergic receptor using the E-state index.
Debnath B; Samanta S; Naskar SK; Roy K; Jha T
Bioorg Med Chem Lett; 2003 Sep; 13(17):2837-42. PubMed ID: 14611840
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]