BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 16720018)

  • 1. 3'-Azido-3'-deoxythymidine (AZT) is a competitive inhibitor of thymidine phosphorylation in isolated rat heart and liver mitochondria.
    Lynx MD; McKee EE
    Biochem Pharmacol; 2006 Jul; 72(2):239-43. PubMed ID: 16720018
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 3'-Azido-3'-deoxythymidine (AZT) inhibits thymidine phosphorylation in isolated rat liver mitochondria: a possible mechanism of AZT hepatotoxicity.
    Lynx MD; Bentley AT; McKee EE
    Biochem Pharmacol; 2006 Apr; 71(9):1342-8. PubMed ID: 16472780
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Zidovudine inhibits thymidine phosphorylation in the isolated perfused rat heart.
    Susan-Resiga D; Bentley AT; Lynx MD; LaClair DD; McKee EE
    Antimicrob Agents Chemother; 2007 Apr; 51(4):1142-9. PubMed ID: 17220403
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phosphorylation of thymidine and AZT in heart mitochondria: elucidation of a novel mechanism of AZT cardiotoxicity.
    McKee EE; Bentley AT; Hatch M; Gingerich J; Susan-Resiga D
    Cardiovasc Toxicol; 2004; 4(2):155-67. PubMed ID: 15371631
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pyrimidine deoxynucleoside and nucleoside reverse transcriptase inhibitor metabolism in the perfused heart and isolated mitochondria.
    Morris GW; Laclair DD; McKee EE
    Antivir Ther; 2010; 15(4):587-97. PubMed ID: 20587852
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effect of AZT on thymidine phosphorylation in cultured H9c2, U-937, and Raji cell lines.
    Lynx MD; Kang BK; McKee EE
    Biochem Pharmacol; 2008 Apr; 75(8):1610-5. PubMed ID: 18295188
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mechanisms of toxicity of 3'-azido-3'-deoxythymidine. Its interaction with adenylate kinase.
    Barile M; Valenti D; Hobbs GA; Abruzzese MF; Keilbaugh SA; Passarella S; Quagliariello E; Simpson MV
    Biochem Pharmacol; 1994 Oct; 48(7):1405-12. PubMed ID: 7945440
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 3'-Azido-3'-deoxythmidine uptake into isolated rat liver mitochondria and impairment of ADP/ATP translocator.
    Barile M; Valenti D; Passarella S; Quagliariello E
    Biochem Pharmacol; 1997 Apr; 53(7):913-20. PubMed ID: 9174103
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cardiac mitochondrial DNA polymerase-gamma is inhibited competitively and noncompetitively by phosphorylated zidovudine.
    Lewis W; Simpson JF; Meyer RR
    Circ Res; 1994 Feb; 74(2):344-8. PubMed ID: 8293572
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Metabolism of deoxypyrimidines and deoxypyrimidine antiviral analogs in isolated brain mitochondria.
    McCann KA; Williams DW; McKee EE
    J Neurochem; 2012 Jul; 122(1):126-37. PubMed ID: 22530558
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A computational model of mitochondrial AZT metabolism.
    Bradshaw PC; Li J; Samuels DC
    Biochem J; 2005 Dec; 392(Pt 2):363-73. PubMed ID: 16060859
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Thymidine and zidovudine metabolism in chronically zidovudine-exposed cells in vitro.
    Agarwal RP; Mian AM
    Biochem Pharmacol; 1991 Jul; 42(4):905-11. PubMed ID: 1867645
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Assessment of mitochondrial toxicity induced by zidovudine and adefovir dipivoxil in rats].
    Zhu B; Zhu ZN; Wang JZ; Huang SM; Feng XM; Li AY; Yang DL; Wang BJ
    Zhonghua Gan Zang Bing Za Zhi; 2012 Oct; 20(10):794-7. PubMed ID: 23207344
    [TBL] [Abstract][Full Text] [Related]  

  • 14. AZT inhibition of the ADP/ATP antiport in isolated rat heart mitochondria.
    Valenti D; Barile M; Passarella S
    Int J Mol Med; 2000 Jul; 6(1):93-6. PubMed ID: 10851273
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 3'-Azido-3'-deoxythymidine cytotoxicity and metabolism in the human colon tumor cell line HCT-8.
    Darnowski JW; Goulette FA
    Biochem Pharmacol; 1994 Nov; 48(9):1797-805. PubMed ID: 7980649
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cellular targets of 3'-azido-3'-deoxythymidine: an early (non-delayed) effect on oxidative phosphorylation.
    Hobbs GA; Keilbaugh SA; Rief PM; Simpson MV
    Biochem Pharmacol; 1995 Jul; 50(3):381-90. PubMed ID: 7646539
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Origin of pyrimidine deoxyribonucleotide pools in perfused rat heart: implications for 3'-azido-3'-deoxythymidine-dependent cardiotoxicity.
    Morris GW; Iams TA; Slepchenko KG; McKee EE
    Biochem J; 2009 Aug; 422(3):513-20. PubMed ID: 19558366
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of phosphate transport in rat heart mitochondria by 3'-azido-3'-deoxythymidine due to stimulation of superoxide anion mitochondrial production.
    Valenti D; Atlante A; Barile M; Passarella S
    Biochem Pharmacol; 2002 Jul; 64(2):201-6. PubMed ID: 12123740
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 2',3'-Dideoxycytidine toxicity in cultured human CEM T lymphoblasts: effects of combination with 3'-azido-3'-deoxythymidine and thymidine.
    Törnevik Y; Eriksson S
    Mol Pharmacol; 1990 Aug; 38(2):237-43. PubMed ID: 2166904
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of thymidine transport by 3'-azido-3'-deoxythymidine and its metabolites.
    Zimmerman TP; Domin BA; Mahony WB
    Oncol Res; 1993; 5(12):483-7. PubMed ID: 8086670
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.