BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

120 related articles for article (PubMed ID: 16720724)

  • 1. FKBP12 functions as an adaptor of the Smad7-Smurf1 complex on activin type I receptor.
    Yamaguchi T; Kurisaki A; Yamakawa N; Minakuchi K; Sugino H
    J Mol Endocrinol; 2006 Jun; 36(3):569-79. PubMed ID: 16720724
    [TBL] [Abstract][Full Text] [Related]  

  • 2. NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor.
    Kuratomi G; Komuro A; Goto K; Shinozaki M; Miyazawa K; Miyazono K; Imamura T
    Biochem J; 2005 Mar; 386(Pt 3):461-70. PubMed ID: 15496141
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phosphorylation regulation of the interaction between Smad7 and activin type I receptor.
    Liu X; Nagarajan RP; Vale W; Chen Y
    FEBS Lett; 2002 May; 519(1-3):93-8. PubMed ID: 12023024
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Smurf1 regulates the inhibitory activity of Smad7 by targeting Smad7 to the plasma membrane.
    Suzuki C; Murakami G; Fukuchi M; Shimanuki T; Shikauchi Y; Imamura T; Miyazono K
    J Biol Chem; 2002 Oct; 277(42):39919-25. PubMed ID: 12151385
    [TBL] [Abstract][Full Text] [Related]  

  • 5. VprBP mitigates TGF-β and Activin signaling by promoting Smurf1-mediated type I receptor degradation.
    Li Y; Cui C; Xie F; Kiełbasa S; Mei H; van Dinther M; van Dam H; Bauer A; Zhang L; Ten Dijke P
    J Mol Cell Biol; 2020 Feb; 12(2):138-151. PubMed ID: 31291647
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1).
    Komuro A; Imamura T; Saitoh M; Yoshida Y; Yamori T; Miyazono K; Miyazawa K
    Oncogene; 2004 Sep; 23(41):6914-23. PubMed ID: 15221015
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation.
    Ebisawa T; Fukuchi M; Murakami G; Chiba T; Tanaka K; Imamura T; Miyazono K
    J Biol Chem; 2001 Apr; 276(16):12477-80. PubMed ID: 11278251
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The immunophilin FKBP12 inhibits hepcidin expression by binding the BMP type I receptor ALK2 in hepatocytes.
    Colucci S; Pagani A; Pettinato M; Artuso I; Nai A; Camaschella C; Silvestri L
    Blood; 2017 Nov; 130(19):2111-2120. PubMed ID: 28864813
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cooperative inhibition of bone morphogenetic protein signaling by Smurf1 and inhibitory Smads.
    Murakami G; Watabe T; Takaoka K; Miyazono K; Imamura T
    Mol Biol Cell; 2003 Jul; 14(7):2809-17. PubMed ID: 12857866
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The N domain of Smad7 is essential for specific inhibition of transforming growth factor-beta signaling.
    Hanyu A; Ishidou Y; Ebisawa T; Shimanuki T; Imamura T; Miyazono K
    J Cell Biol; 2001 Dec; 155(6):1017-27. PubMed ID: 11739411
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Crk-associated substrate lymphocyte type regulates transforming growth factor-beta signaling by inhibiting Smad6 and Smad7.
    Inamoto S; Iwata S; Inamoto T; Nomura S; Sasaki T; Urasaki Y; Hosono O; Kawasaki H; Tanaka H; Dang NH; Morimoto C
    Oncogene; 2007 Feb; 26(6):893-904. PubMed ID: 16909115
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Chromosomal region maintenance 1 (CRM1)-dependent nuclear export of Smad ubiquitin regulatory factor 1 (Smurf1) is essential for negative regulation of transforming growth factor-beta signaling by Smad7.
    Tajima Y; Goto K; Yoshida M; Shinomiya K; Sekimoto T; Yoneda Y; Miyazono K; Imamura T
    J Biol Chem; 2003 Mar; 278(12):10716-21. PubMed ID: 12519765
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Control of Smad7 stability by competition between acetylation and ubiquitination.
    Grönroos E; Hellman U; Heldin CH; Ericsson J
    Mol Cell; 2002 Sep; 10(3):483-93. PubMed ID: 12408818
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The immunophilin FKBP12 functions as a common inhibitor of the TGF beta family type I receptors.
    Wang T; Li BY; Danielson PD; Shah PC; Rockwell S; Lechleider RJ; Martin J; Manganaro T; Donahoe PK
    Cell; 1996 Aug; 86(3):435-44. PubMed ID: 8756725
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Down-regulation of Smad7 expression by ubiquitin-dependent degradation contributes to renal fibrosis in obstructive nephropathy in mice.
    Fukasawa H; Yamamoto T; Togawa A; Ohashi N; Fujigaki Y; Oda T; Uchida C; Kitagawa K; Hattori T; Suzuki S; Kitagawa M; Hishida A
    Proc Natl Acad Sci U S A; 2004 Jun; 101(23):8687-92. PubMed ID: 15173588
    [TBL] [Abstract][Full Text] [Related]  

  • 16. FKBP12 is a major regulator of ALK2 activity in multiple myeloma cells.
    Quist-Løkken I; Andersson-Rusch C; Kastnes MH; Kolos JM; Jatzlau J; Hella H; Olsen OE; Sundan A; Knaus P; Hausch F; Holien T
    Cell Commun Signal; 2023 Jan; 21(1):25. PubMed ID: 36717825
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Arkadia-Smad7-mediated positive regulation of TGF-beta signaling in a rat model of tubulointerstitial fibrosis.
    Liu FY; Li XZ; Peng YM; Liu H; Liu YH
    Am J Nephrol; 2007; 27(2):176-83. PubMed ID: 17347560
    [TBL] [Abstract][Full Text] [Related]  

  • 18. TGF-beta-signaling with small molecule FKBP12 antagonists that bind myristoylated FKBP12-TGF-beta type I receptor fusion proteins.
    Stockwell BR; Schreiber SL
    Chem Biol; 1998 Jul; 5(7):385-95. PubMed ID: 9662508
    [TBL] [Abstract][Full Text] [Related]  

  • 19. FKBP12, the 12-kDa FK506-binding protein, is a physiologic regulator of the cell cycle.
    Aghdasi B; Ye K; Resnick A; Huang A; Ha HC; Guo X; Dawson TM; Dawson VL; Snyder SH
    Proc Natl Acad Sci U S A; 2001 Feb; 98(5):2425-30. PubMed ID: 11226255
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Itch E3 ubiquitin ligase positively regulates TGF-β signaling to EMT via Smad7 ubiquitination.
    Park SH; Jung EH; Kim GY; Kim BC; Lim JH; Woo CH
    Mol Cells; 2015 Jan; 38(1):20-5. PubMed ID: 25518932
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.