233 related articles for article (PubMed ID: 16722636)
1. Design, molecular modeling, synthesis, and anti-HIV-1 activity of new indolyl aryl sulfones. Novel derivatives of the indole-2-carboxamide.
Ragno R; Coluccia A; La Regina G; De Martino G; Piscitelli F; Lavecchia A; Novellino E; Bergamini A; Ciaprini C; Sinistro A; Maga G; Crespan E; Artico M; Silvestri R
J Med Chem; 2006 Jun; 49(11):3172-84. PubMed ID: 16722636
[TBL] [Abstract][Full Text] [Related]
2. Indolyl aryl sulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors: role of two halogen atoms at the indole ring in developing new analogues with improved antiviral activity.
Regina GL; Coluccia A; Piscitelli F; Bergamini A; Sinistro A; Cavazza A; Maga G; Samuele A; Zanoli S; Novellino E; Artico M; Silvestri R
J Med Chem; 2007 Oct; 50(20):5034-8. PubMed ID: 17803291
[TBL] [Abstract][Full Text] [Related]
3. Novel indolyl aryl sulfones active against HIV-1 carrying NNRTI resistance mutations: synthesis and SAR studies.
Silvestri R; De Martino G; La Regina G; Artico M; Massa S; Vargiu L; Mura M; Loi AG; Marceddu T; La Colla P
J Med Chem; 2003 Jun; 46(12):2482-93. PubMed ID: 12773052
[TBL] [Abstract][Full Text] [Related]
4. Indolylarylsulfones bearing natural and unnatural amino acids. Discovery of potent inhibitors of HIV-1 non-nucleoside wild type and resistant mutant strains reverse transcriptase and coxsackie B4 virus.
Piscitelli F; Coluccia A; Brancale A; La Regina G; Sansone A; Giordano C; Balzarini J; Maga G; Zanoli S; Samuele A; Cirilli R; La Torre F; Lavecchia A; Novellino E; Silvestri R
J Med Chem; 2009 Apr; 52(7):1922-34. PubMed ID: 19281225
[TBL] [Abstract][Full Text] [Related]
5. Docking and 3-D QSAR studies on indolyl aryl sulfones. Binding mode exploration at the HIV-1 reverse transcriptase non-nucleoside binding site and design of highly active N-(2-hydroxyethyl)carboxamide and N-(2-hydroxyethyl)carbohydrazide derivatives.
Ragno R; Artico M; De Martino G; La Regina G; Coluccia A; Di Pasquali A; Silvestri R
J Med Chem; 2005 Jan; 48(1):213-23. PubMed ID: 15634015
[TBL] [Abstract][Full Text] [Related]
6. Indolylarylsulfones as HIV-1 non-nucleoside reverse transcriptase inhibitors: new cyclic substituents at indole-2-carboxamide.
La Regina G; Coluccia A; Brancale A; Piscitelli F; Gatti V; Maga G; Samuele A; Pannecouque C; Schols D; Balzarini J; Novellino E; Silvestri R
J Med Chem; 2011 Mar; 54(6):1587-98. PubMed ID: 21366296
[TBL] [Abstract][Full Text] [Related]
7. Indolyl aryl sulfones (IASs): development of highly potent NNRTIs active against wt-HIV-1 and clinically relevant drug resistant mutants.
Silvestri R; Artico M
Curr Pharm Des; 2005; 11(29):3779-806. PubMed ID: 16305512
[TBL] [Abstract][Full Text] [Related]
8. Simple, short peptide derivatives of a sulfonylindolecarboxamide (L-737,126) active in vitro against HIV-1 wild type and variants carrying non-nucleoside reverse transcriptase inhibitor resistance mutations.
Silvestri R; Artico M; De Martino G; La Regina G; Loddo R; La Colla M; Mura M; La Colla P
J Med Chem; 2004 Jul; 47(15):3892-6. PubMed ID: 15239667
[TBL] [Abstract][Full Text] [Related]
9. Sulfone derivatives with anti-HIV activity.
Silvestri R; Artico M; Massa S; Stefancich G; Congeddu E; Putzolu M; La Colla P
Farmaco; 1997 May; 52(5):323-9. PubMed ID: 9274003
[TBL] [Abstract][Full Text] [Related]
10. Non-nucleoside HIV-1 reverse transcriptase inhibitors di-halo-indolyl aryl sulfones achieve tight binding to drug-resistant mutants by targeting the enzyme-substrate complex.
Samuele A; Kataropoulou A; Viola M; Zanoli S; La Regina G; Piscitelli F; Silvestri R; Maga G
Antiviral Res; 2009 Jan; 81(1):47-55. PubMed ID: 18984007
[TBL] [Abstract][Full Text] [Related]
11. Indolylarylsulfones carrying a heterocyclic tail as very potent and broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitors.
Famiglini V; La Regina G; Coluccia A; Pelliccia S; Brancale A; Maga G; Crespan E; Badia R; Riveira-Muñoz E; Esté JA; Ferretti R; Cirilli R; Zamperini C; Botta M; Schols D; Limongelli V; Agostino B; Novellino E; Silvestri R
J Med Chem; 2014 Dec; 57(23):9945-57. PubMed ID: 25418038
[TBL] [Abstract][Full Text] [Related]
12. Discovery of novel indolylarylsulfones as potent HIV-1 NNRTIs via structure-guided scaffold morphing.
Zhao T; Meng Q; Kang D; Ji J; De Clercq E; Pannecouque C; Liu X; Zhan P
Eur J Med Chem; 2019 Nov; 182():111619. PubMed ID: 31434039
[TBL] [Abstract][Full Text] [Related]
13. New nitrogen containing substituents at the indole-2-carboxamide yield high potent and broad spectrum indolylarylsulfone HIV-1 non-nucleoside reverse transcriptase inhibitors.
La Regina G; Coluccia A; Brancale A; Piscitelli F; Famiglini V; Cosconati S; Maga G; Samuele A; Gonzalez E; Clotet B; Schols D; Esté JA; Novellino E; Silvestri R
J Med Chem; 2012 Jul; 55(14):6634-8. PubMed ID: 22712652
[TBL] [Abstract][Full Text] [Related]
14. 2-Sulfonyl-4-chloroanilino moiety: a potent pharmacophore for the anti-human immunodeficiency virus type 1 activity of pyrrolyl aryl sulfones.
Artico M; Silvestri R; Massa S; Loi AG; Corrias S; Piras G; La Colla P
J Med Chem; 1996 Jan; 39(2):522-30. PubMed ID: 8558522
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and biological properties of novel pyridinioalkanoyl thiolesters (PATE) as anti-HIV-1 agents that target the viral nucleocapsid protein zinc fingers.
Turpin JA; Song Y; Inman JK; Huang M; Wallqvist A; Maynard A; Covell DG; Rice WG; Appella E
J Med Chem; 1999 Jan; 42(1):67-86. PubMed ID: 9888834
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and biological evaluation of 5H-indolo [3,2-b][1,5]benzothiazepine derivatives, designed as conformationally constrained analogues of the human immunodeficiency virus type 1 reverse transcriptase inhibitor L-737,126.
Silvestri R; Artico M; Bruno B; Massa S; Novellino E; Greco G; Marongiu ME; Pani A; De Montis A; La Colla P
Antivir Chem Chemother; 1998 Mar; 9(2):139-48. PubMed ID: 9875385
[TBL] [Abstract][Full Text] [Related]
17. Design, synthesis, biological evaluation, and molecular modeling studies of TIBO-like cyclic sulfones as non-nucleoside HIV-1 reverse transcriptase inhibitors.
Di Santo R; Costi R; Artico M; Ragno R; Lavecchia A; Novellino E; Gavuzzo E; La Torre F; Cirilli R; Cancio R; Maga G
ChemMedChem; 2006 Jan; 1(1):82-95. PubMed ID: 16892340
[TBL] [Abstract][Full Text] [Related]
18. Design and synthesis of novel indole beta-diketo acid derivatives as HIV-1 integrase inhibitors.
Sechi M; Derudas M; Dallocchio R; Dessì A; Bacchi A; Sannia L; Carta F; Palomba M; Ragab O; Chan C; Shoemaker R; Sei S; Dayam R; Neamati N
J Med Chem; 2004 Oct; 47(21):5298-310. PubMed ID: 15456274
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and evaluation of 2-(2,6-dihalophenyl)-3-pyrimidinyl-1,3-thiazolidin-4-one analogues as anti-HIV-1 agents.
Rawal RK; Tripathi R; Katti SB; Pannecouque C; De Clercq E
Bioorg Med Chem; 2007 May; 15(9):3134-42. PubMed ID: 17349793
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and biological properties of novel 2-aminopyrimidin-4(3H)-ones highly potent against HIV-1 mutant strains.
Mai A; Artico M; Rotili D; Tarantino D; Clotet-Codina I; Armand-Ugón M; Ragno R; Simeoni S; Sbardella G; Nawrozkij MB; Samuele A; Maga G; Esté JA
J Med Chem; 2007 Nov; 50(22):5412-24. PubMed ID: 17910429
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]