818 related articles for article (PubMed ID: 1672265)
1. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation.
Vu TK; Hung DT; Wheaton VI; Coughlin SR
Cell; 1991 Mar; 64(6):1057-68. PubMed ID: 1672265
[TBL] [Abstract][Full Text] [Related]
2. Tethered ligand agonist peptides. Structural requirements for thrombin receptor activation reveal mechanism of proteolytic unmasking of agonist function.
Scarborough RM; Naughton MA; Teng W; Hung DT; Rose J; Vu TK; Wheaton VI; Turck CW; Coughlin SR
J Biol Chem; 1992 Jul; 267(19):13146-9. PubMed ID: 1320011
[TBL] [Abstract][Full Text] [Related]
3. Thrombin-induced events in non-platelet cells are mediated by the unique proteolytic mechanism established for the cloned platelet thrombin receptor.
Hung DT; Vu TH; Nelken NA; Coughlin SR
J Cell Biol; 1992 Feb; 116(3):827-32. PubMed ID: 1309820
[TBL] [Abstract][Full Text] [Related]
4. Domains specifying thrombin-receptor interaction.
Vu TK; Wheaton VI; Hung DT; Charo I; Coughlin SR
Nature; 1991 Oct; 353(6345):674-7. PubMed ID: 1717851
[TBL] [Abstract][Full Text] [Related]
5. Immunologic analysis of the cloned platelet thrombin receptor activation mechanism: evidence supporting receptor cleavage, release of the N-terminal peptide, and insertion of the tethered ligand into a protected environment.
Norton KJ; Scarborough RM; Kutok JL; Escobedo MA; Nannizzi L; Coller BS
Blood; 1993 Oct; 82(7):2125-36. PubMed ID: 8400262
[TBL] [Abstract][Full Text] [Related]
6. Thrombin receptor activation. Confirmation of the intramolecular tethered liganding hypothesis and discovery of an alternative intermolecular liganding mode.
Chen J; Ishii M; Wang L; Ishii K; Coughlin SR
J Biol Chem; 1994 Jun; 269(23):16041-5. PubMed ID: 8206902
[TBL] [Abstract][Full Text] [Related]
7. Tethered ligand library for discovery of peptide agonists.
Chen J; Bernstein HS; Chen M; Wang L; Ishii M; Turck CW; Coughlin SR
J Biol Chem; 1995 Oct; 270(40):23398-401. PubMed ID: 7559498
[TBL] [Abstract][Full Text] [Related]
8. A dual thrombin receptor system for platelet activation.
Kahn ML; Zheng YW; Huang W; Bigornia V; Zeng D; Moff S; Farese RV; Tam C; Coughlin SR
Nature; 1998 Aug; 394(6694):690-4. PubMed ID: 9716134
[TBL] [Abstract][Full Text] [Related]
9. Plasmin desensitization of the PAR1 thrombin receptor: kinetics, sites of truncation, and implications for thrombolytic therapy.
Kuliopulos A; Covic L; Seeley SK; Sheridan PJ; Helin J; Costello CE
Biochemistry; 1999 Apr; 38(14):4572-85. PubMed ID: 10194379
[TBL] [Abstract][Full Text] [Related]
10. The thrombin receptor.
Dennington PM; Berndt MC
Clin Exp Pharmacol Physiol; 1994 May; 21(5):349-58. PubMed ID: 7955544
[TBL] [Abstract][Full Text] [Related]
11. Expression of functional thrombin receptors in xenopus oocytes injected with human endothelial cell mRNA.
Pipili-Synetos E; Gershengorn MC; Jaffe EA
Biochem Biophys Res Commun; 1990 Sep; 171(3):913-9. PubMed ID: 1699530
[TBL] [Abstract][Full Text] [Related]
12. The thrombin receptor extracellular domain contains sites crucial for peptide ligand-induced activation.
Bahou WF; Coller BS; Potter CL; Norton KJ; Kutok JL; Goligorsky MS
J Clin Invest; 1993 Apr; 91(4):1405-13. PubMed ID: 8386186
[TBL] [Abstract][Full Text] [Related]
13. Identification of a novel thrombin receptor sequence required for activation-dependent responses.
Bahou WF; Kutok JL; Wong A; Potter CL; Coller BS
Blood; 1994 Dec; 84(12):4195-202. PubMed ID: 7994033
[TBL] [Abstract][Full Text] [Related]
14. Determinants of thrombin receptor cleavage. Receptor domains involved, specificity, and role of the P3 aspartate.
Ishii K; Gerszten R; Zheng YW; Welsh JB; Turck CW; Coughlin SR
J Biol Chem; 1995 Jul; 270(27):16435-40. PubMed ID: 7608215
[TBL] [Abstract][Full Text] [Related]
15. Synthetic alpha-thrombin receptor peptides activate G protein-coupled signaling pathways but are unable to induce mitogenesis.
Vouret-Craviari V; Van Obberghen-Schilling E; Rasmussen UB; Pavirani A; Lecocq JP; Pouysségur J
Mol Biol Cell; 1992 Jan; 3(1):95-102. PubMed ID: 1312881
[TBL] [Abstract][Full Text] [Related]
16. Protease-activated receptor-1 can mediate responses to SFLLRN in thrombin-desensitized cells: evidence for a novel mechanism for preventing or terminating signaling by PAR1's tethered ligand.
Hammes SR; Coughlin SR
Biochemistry; 1999 Feb; 38(8):2486-93. PubMed ID: 10029543
[TBL] [Abstract][Full Text] [Related]
17. Cloned platelet thrombin receptor is necessary for thrombin-induced platelet activation.
Hung DT; Vu TK; Wheaton VI; Ishii K; Coughlin SR
J Clin Invest; 1992 Apr; 89(4):1350-3. PubMed ID: 1313452
[TBL] [Abstract][Full Text] [Related]
18. cDNA cloning and expression of a hamster alpha-thrombin receptor coupled to Ca2+ mobilization.
Rasmussen UB; Vouret-Craviari V; Jallat S; Schlesinger Y; Pagès G; Pavirani A; Lecocq JP; Pouysségur J; Van Obberghen-Schilling E
FEBS Lett; 1991 Aug; 288(1-2):123-8. PubMed ID: 1652467
[TBL] [Abstract][Full Text] [Related]
19. Specificity of the thrombin receptor for agonist peptide is defined by its extracellular surface.
Gerszten RE; Chen J; Ishii M; Ishii K; Wang L; Nanevicz T; Turck CW; Vu TK; Coughlin SR
Nature; 1994 Apr; 368(6472):648-51. PubMed ID: 8145852
[TBL] [Abstract][Full Text] [Related]
20. Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes.
Mathews II; Padmanabhan KP; Ganesh V; Tulinsky A; Ishii M; Chen J; Turck CW; Coughlin SR; Fenton JW
Biochemistry; 1994 Mar; 33(11):3266-79. PubMed ID: 8136362
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
