Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

535 related articles for article (PubMed ID: 16723399)

  • 1. Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer.
    Agrelo R; Cheng WH; Setien F; Ropero S; Espada J; Fraga MF; Herranz M; Paz MF; Sanchez-Cespedes M; Artiga MJ; Guerrero D; Castells A; von Kobbe C; Bohr VA; Esteller M
    Proc Natl Acad Sci U S A; 2006 Jun; 103(23):8822-7. PubMed ID: 16723399
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Role for the Werner syndrome protein in the promotion of tumor cell growth.
    Opresko PL; Calvo JP; von Kobbe C
    Mech Ageing Dev; 2007; 128(7-8):423-36. PubMed ID: 17624410
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Association of epigenetic inactivation of the WRN gene with anticancer drug sensitivity in cervical cancer cells.
    Masuda K; Banno K; Yanokura M; Tsuji K; Kobayashi Y; Kisu I; Ueki A; Yamagami W; Nomura H; Tominaga E; Susumu N; Aoki D
    Oncol Rep; 2012 Oct; 28(4):1146-52. PubMed ID: 22797812
    [TBL] [Abstract][Full Text] [Related]  

  • 4. WRN helicase defective in the premature aging disorder Werner syndrome genetically interacts with topoisomerase 3 and restores the top3 slow growth phenotype of sgs1 top3.
    Aggarwal M; Brosh RM
    Aging (Albany NY); 2009 Feb; 1(2):219-33. PubMed ID: 20157511
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Epigenetic loss of the familial tumor-suppressor gene exostosin-1 (EXT1) disrupts heparan sulfate synthesis in cancer cells.
    Ropero S; Setien F; Espada J; Fraga MF; Herranz M; Asp J; Benassi MS; Franchi A; PatiƱo A; Ward LS; Bovee J; Cigudosa JC; Wim W; Esteller M
    Hum Mol Genet; 2004 Nov; 13(22):2753-65. PubMed ID: 15385438
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Werner syndrome protein contributes to induction of p53 by DNA damage.
    Blander G; Zalle N; Leal JF; Bar-Or RL; Yu CE; Oren M
    FASEB J; 2000 Nov; 14(14):2138-40. PubMed ID: 11023999
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Werner syndrome as a hereditary risk factor for exocrine pancreatic cancer: potential role of WRN in pancreatic tumorigenesis and patient-tailored therapy.
    Chun SG; Yee NS
    Cancer Biol Ther; 2010 Sep; 10(5):430-7. PubMed ID: 20657174
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Preferential expression of an intact WRN gene in Werner syndrome cell lines in which a normal chromosome 8 has been introduced.
    Kashino G; Kodama S; Suzuki K; Oshimura M; Watanabe M
    Biochem Biophys Res Commun; 2001 Nov; 289(1):111-5. PubMed ID: 11708785
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Epigenetic gene silencing in cancer: the DNA hypermethylome.
    Esteller M
    Hum Mol Genet; 2007 Apr; 16 Spec No 1():R50-9. PubMed ID: 17613547
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Werner syndrome protein limits MYC-induced cellular senescence.
    Grandori C; Wu KJ; Fernandez P; Ngouenet C; Grim J; Clurman BE; Moser MJ; Oshima J; Russell DW; Swisshelm K; Frank S; Amati B; Dalla-Favera R; Monnat RJ
    Genes Dev; 2003 Jul; 17(13):1569-74. PubMed ID: 12842909
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Genetic cooperation between the Werner syndrome protein and poly(ADP-ribose) polymerase-1 in preventing chromatid breaks, complex chromosomal rearrangements, and cancer in mice.
    Lebel M; Lavoie J; Gaudreault I; Bronsard M; Drouin R
    Am J Pathol; 2003 May; 162(5):1559-69. PubMed ID: 12707040
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Werner syndrome gene: the molecular basis of RecQ helicase-deficiency diseases.
    Shen JC; Loeb LA
    Trends Genet; 2000 May; 16(5):213-20. PubMed ID: 10782115
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A novel Werner Syndrome mutation: pharmacological treatment by read-through of nonsense mutations and epigenetic therapies.
    Agrelo R; Sutz MA; Setien F; Aldunate F; Esteller M; Da Costa V; Achenbach R
    Epigenetics; 2015; 10(4):329-41. PubMed ID: 25830902
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Increased frequency of DNA deletions in pink-eyed unstable mice carrying a mutation in the Werner syndrome gene homologue.
    Lebel M
    Carcinogenesis; 2002 Jan; 23(1):213-6. PubMed ID: 11756244
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Werner syndrome protein: an update.
    Oshima J
    Bioessays; 2000 Oct; 22(10):894-901. PubMed ID: 10984715
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Werner syndrome protein prevents DNA breaks upon chromatin structure alteration.
    Turaga RV; Massip L; Chavez A; Johnson FB; Lebel M
    Aging Cell; 2007 Aug; 6(4):471-81. PubMed ID: 17521388
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Werner protein stimulates topoisomerase I DNA relaxation activity.
    Laine JP; Opresko PL; Indig FE; Harrigan JA; von Kobbe C; Bohr VA
    Cancer Res; 2003 Nov; 63(21):7136-46. PubMed ID: 14612507
    [TBL] [Abstract][Full Text] [Related]  

  • 18. WRN mutations in Werner syndrome.
    Moser MJ; Oshima J; Monnat RJ
    Hum Mutat; 1999; 13(4):271-9. PubMed ID: 10220139
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of Werner syndrome gene product helicase in carcinogenesis and in resistance to genotoxins by cancer cells.
    Futami K; Ishikawa Y; Goto M; Furuichi Y; Sugimoto M
    Cancer Sci; 2008 May; 99(5):843-8. PubMed ID: 18312465
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cellular Werner phenotypes in mice expressing a putative dominant-negative human WRN gene.
    Wang L; Ogburn CE; Ware CB; Ladiges WC; Youssoufian H; Martin GM; Oshima J
    Genetics; 2000 Jan; 154(1):357-62. PubMed ID: 10628995
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 27.