124 related articles for article (PubMed ID: 16730244)
1. LC-MS/MS assay and dog pharmacokinetics of the dimeric pyrrolobenzodiazepine SJG-136 (NSC 694501).
Buhrow SA; Reid JM; Jia L; McGovern RM; Covey JM; Kobs DJ; Grossi IM; Ames MM
J Chromatogr B Analyt Technol Biomed Life Sci; 2006 Aug; 840(1):56-62. PubMed ID: 16730244
[TBL] [Abstract][Full Text] [Related]
2. Determination of chemically reduced pyrrolobenzodiazepine SJG-136 in human plasma by HPLC-MS/MS: application to an anticancer phase I dose escalation study.
Wade Calcutt M; Lee W; Puzanov I; Rothenberg ML; Hachey DL
J Mass Spectrom; 2008 Jan; 43(1):42-52. PubMed ID: 17683023
[TBL] [Abstract][Full Text] [Related]
3. SJG-136 (NSC 694501), a novel rationally designed DNA minor groove interstrand cross-linking agent with potent and broad spectrum antitumor activity: part 1: cellular pharmacology, in vitro and initial in vivo antitumor activity.
Hartley JA; Spanswick VJ; Brooks N; Clingen PH; McHugh PJ; Hochhauser D; Pedley RB; Kelland LR; Alley MC; Schultz R; Hollingshead MG; Schweikart KM; Tomaszewski JE; Sausville EA; Gregson SJ; Howard PW; Thurston DE
Cancer Res; 2004 Sep; 64(18):6693-9. PubMed ID: 15374986
[TBL] [Abstract][Full Text] [Related]
4. Pharmacokinetics, pharmacodynamics and metabolism of the dimeric pyrrolobenzodiazepine SJG-136 in rats.
Reid JM; Buhrow SA; Kuffel MJ; Jia L; Spanswick VJ; Hartley JA; Thurston DE; Tomaszewski JE; Ames MM
Cancer Chemother Pharmacol; 2011 Sep; 68(3):777-86. PubMed ID: 21188379
[TBL] [Abstract][Full Text] [Related]
5. Preliminary pharmacokinetic and bioanalytical studies of SJG-136 (NSC 694501), a sequence-selective pyrrolobenzodiazepine dimer DNA-cross-linking agent.
Wilkinson GP; Taylor JP; Shnyder S; Cooper P; Howard PW; Thurston DE; Jenkins TC; Loadman PM
Invest New Drugs; 2004 Aug; 22(3):231-40. PubMed ID: 15122070
[TBL] [Abstract][Full Text] [Related]
6. Direct liquid chromatography determination of the reactive imine SJG-136 (NSC 694501).
Cheung A; Struble E; He J; Yang C; Wang E; Thurston DE; Liu P
J Chromatogr B Analyt Technol Biomed Life Sci; 2005 Aug; 822(1-2):10-20. PubMed ID: 15994138
[TBL] [Abstract][Full Text] [Related]
7. SJG-136 (NSC 694501), a novel rationally designed DNA minor groove interstrand cross-linking agent with potent and broad spectrum antitumor activity: part 2: efficacy evaluations.
Alley MC; Hollingshead MG; Pacula-Cox CM; Waud WR; Hartley JA; Howard PW; Gregson SJ; Thurston DE; Sausville EA
Cancer Res; 2004 Sep; 64(18):6700-6. PubMed ID: 15374987
[TBL] [Abstract][Full Text] [Related]
8. Sequence-selective interaction of the minor-groove interstrand cross-linking agent SJG-136 with naked and cellular DNA: footprinting and enzyme inhibition studies.
Martin C; Ellis T; McGurk CJ; Jenkins TC; Hartley JA; Waring MJ; Thurston DE
Biochemistry; 2005 Mar; 44(11):4135-47. PubMed ID: 15766241
[TBL] [Abstract][Full Text] [Related]
9. An assay combining high-performance liquid chromatography and mass spectrometry to measure DNA interstrand cross-linking efficiency in oligonucleotides of varying sequences.
Narayanaswamy M; Griffiths WJ; Howard PW; Thurston DE
Anal Biochem; 2008 Mar; 374(1):173-81. PubMed ID: 18082123
[TBL] [Abstract][Full Text] [Related]
10. High performance liquid chromatographic analysis and preclinical pharmacokinetics of the heteroarotinoid antitumor agent, SHetA2.
Zhang Y; Hua Y; Benbrook DM; Covey JM; Dai G; Liu Z; Chan KK
Cancer Chemother Pharmacol; 2006 Nov; 58(5):561-9. PubMed ID: 16534614
[TBL] [Abstract][Full Text] [Related]
11. Determination of tegaserod by LC-ESI-MS/MS and its application to a pharmacokinetic study in healthy Chinese volunteers.
Zou JJ; Bian XJ; Ding L; Zhu YB; Fan HW; Xiao DW
J Chromatogr B Analyt Technol Biomed Life Sci; 2008 Jan; 861(1):151-7. PubMed ID: 18069077
[TBL] [Abstract][Full Text] [Related]
12. Influence of P-glycoprotein expression on in vitro cytotoxicity and in vivo antitumour activity of the novel pyrrolobenzodiazepine dimer SJG-136.
Guichard SM; Macpherson JS; Thurston DE; Jodrell DI
Eur J Cancer; 2005 Aug; 41(12):1811-8. PubMed ID: 16046116
[TBL] [Abstract][Full Text] [Related]
13. Development and validation of a liquid chromatography/tandem mass spectrometry assay for the simultaneous determination of D-amphetamine and diphenhydramine in beagle dog plasma and its application to a pharmacokinetic study.
Wang C; Fan G; Lin M; Chen Y; Zhao W; Wu Y
J Chromatogr B Analyt Technol Biomed Life Sci; 2007 Jul; 854(1-2):48-56. PubMed ID: 17452029
[TBL] [Abstract][Full Text] [Related]
14. Development of a liquid chromatography/tandem mass spectrometry assay for the determination of bestatin in rat plasma and its application to a pharmacokinetic study.
Wang C; Fan G; Lin M; Chen Y; Zhao W; Wu Y
J Chromatogr B Analyt Technol Biomed Life Sci; 2007 May; 850(1-2):101-8. PubMed ID: 17141585
[TBL] [Abstract][Full Text] [Related]
15. A liquid chromatography-mass spectrometry assay for simultaneous determination of two antimalarial thiazolium compounds in human and rat matrices.
Taudon N; Margout D; Calas M; Kezutyte T; Vial HJ; Bressolle FM
J Pharm Biomed Anal; 2008 Nov; 48(3):1001-5. PubMed ID: 18678456
[TBL] [Abstract][Full Text] [Related]
16. Sensitive quantification of ranolazine in human plasma by liquid chromatography--tandem mass spectrometry with positive electrospray ionization.
Tian L; Jiang J; Huang Y; Hua L; Liu H; Li Y
J Chromatogr B Analyt Technol Biomed Life Sci; 2007 Feb; 846(1-2):346-50. PubMed ID: 16959552
[TBL] [Abstract][Full Text] [Related]
17. A high throughput and sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the estimation of bisoprolol in human plasma using multiplexing technique.
Bhatt J; Subbaiah G; Kambli S; Shah B; Patel M; Saxena A; Baliga A; Nigam S; Parekh H; Yadav G
J Chromatogr B Analyt Technol Biomed Life Sci; 2007 Jun; 852(1-2):374-81. PubMed ID: 17324642
[TBL] [Abstract][Full Text] [Related]
18. Validated LC-MS/MS assay for the determination of felbinac: Application to a preclinical pharmacokinetics study of felbinac trometamol injection in rat.
Zhang C; Wang L; Yang W; Wang X; Fawcett JP; Sun Y; Gu J
J Pharm Biomed Anal; 2009 Aug; 50(1):41-5. PubMed ID: 19376665
[TBL] [Abstract][Full Text] [Related]
19. Determination of acyclovir in horse plasma and body fluids by high-performance liquid chromatography combined with fluorescence detection and heated electrospray ionization tandem mass spectrometry.
Maes A; Garré B; Desmet N; van der Meulen K; Nauwynck H; De Backer P; Croubels S
Biomed Chromatogr; 2009 Feb; 23(2):132-40. PubMed ID: 18823074
[TBL] [Abstract][Full Text] [Related]
20. A sensitive assay for the quantitative analysis of vinorelbine in mouse and human EDTA plasma by high-performance liquid chromatography coupled with electrospray tandem mass spectrometry.
Damen CW; Rosing H; Tibben MM; van Maanen MJ; Lagas JS; Schinkel AH; Schellens JH; Beijnen JH
J Chromatogr B Analyt Technol Biomed Life Sci; 2008 Jun; 868(1-2):102-9. PubMed ID: 18501686
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
