263 related articles for article (PubMed ID: 16740734)
1. Mechanism of apoptosis induced by the inhibition of fatty acid synthase in breast cancer cells.
Bandyopadhyay S; Zhan R; Wang Y; Pai SK; Hirota S; Hosobe S; Takano Y; Saito K; Furuta E; Iiizumi M; Mohinta S; Watabe M; Chalfant C; Watabe K
Cancer Res; 2006 Jun; 66(11):5934-40. PubMed ID: 16740734
[TBL] [Abstract][Full Text] [Related]
2. RNA interference-mediated silencing of the p53 tumor-suppressor protein drastically increases apoptosis after inhibition of endogenous fatty acid metabolism in breast cancer cells.
Menendez JA; Lupu R
Int J Mol Med; 2005 Jan; 15(1):33-40. PubMed ID: 15583825
[TBL] [Abstract][Full Text] [Related]
3. Overexpression and hyperactivity of breast cancer-associated fatty acid synthase (oncogenic antigen-519) is insensitive to normal arachidonic fatty acid-induced suppression in lipogenic tissues but it is selectively inhibited by tumoricidal alpha-linolenic and gamma-linolenic fatty acids: a novel mechanism by which dietary fat can alter mammary tumorigenesis.
Menendez JA; Ropero S; Mehmi I; Atlas E; Colomer R; Lupu R
Int J Oncol; 2004 Jun; 24(6):1369-83. PubMed ID: 15138577
[TBL] [Abstract][Full Text] [Related]
4. Fatty acid synthase inhibition triggers apoptosis during S phase in human cancer cells.
Zhou W; Simpson PJ; McFadden JM; Townsend CA; Medghalchi SM; Vadlamudi A; Pinn ML; Ronnett GV; Kuhajda FP
Cancer Res; 2003 Nov; 63(21):7330-7. PubMed ID: 14612531
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of fatty acid synthase-dependent neoplastic lipogenesis as the mechanism of gamma-linolenic acid-induced toxicity to tumor cells: an extension to Nwankwo's hypothesis.
Menendez JA; Colomer R; Lupu R
Med Hypotheses; 2005; 64(2):337-41. PubMed ID: 15607568
[TBL] [Abstract][Full Text] [Related]
6. Synergistic induction of apoptosis in breast cancer cells by cotreatment with butyrate and TNF-alpha, TRAIL, or anti-Fas agonist antibody involves enhancement of death receptors' signaling and requires P21(waf1).
Chopin V; Slomianny C; Hondermarck H; Le Bourhis X
Exp Cell Res; 2004 Aug; 298(2):560-73. PubMed ID: 15265702
[TBL] [Abstract][Full Text] [Related]
7. Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoA-induced inhibition of fatty acid oxidation and cytotoxicity.
Thupari JN; Pinn ML; Kuhajda FP
Biochem Biophys Res Commun; 2001 Jul; 285(2):217-23. PubMed ID: 11444828
[TBL] [Abstract][Full Text] [Related]
8. Fatty acid synthase gene is up-regulated by hypoxia via activation of Akt and sterol regulatory element binding protein-1.
Furuta E; Pai SK; Zhan R; Bandyopadhyay S; Watabe M; Mo YY; Hirota S; Hosobe S; Tsukada T; Miura K; Kamada S; Saito K; Iiizumi M; Liu W; Ericsson J; Watabe K
Cancer Res; 2008 Feb; 68(4):1003-11. PubMed ID: 18281474
[TBL] [Abstract][Full Text] [Related]
9. RNA interference-mediated silencing of the acetyl-CoA-carboxylase-alpha gene induces growth inhibition and apoptosis of prostate cancer cells.
Brusselmans K; De Schrijver E; Verhoeven G; Swinnen JV
Cancer Res; 2005 Aug; 65(15):6719-25. PubMed ID: 16061653
[TBL] [Abstract][Full Text] [Related]
10. Tea polyphenol (-)-epigallocatechin 3-gallate suppresses heregulin-beta1-induced fatty acid synthase expression in human breast cancer cells by inhibiting phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase cascade signaling.
Pan MH; Lin CC; Lin JK; Chen WJ
J Agric Food Chem; 2007 Jun; 55(13):5030-7. PubMed ID: 17539658
[TBL] [Abstract][Full Text] [Related]
11. Acetyl-CoA carboxylase alpha is essential to breast cancer cell survival.
Chajès V; Cambot M; Moreau K; Lenoir GM; Joulin V
Cancer Res; 2006 May; 66(10):5287-94. PubMed ID: 16707454
[TBL] [Abstract][Full Text] [Related]
12. The estrogenic activity of synthetic progestins used in oral contraceptives enhances fatty acid synthase-dependent breast cancer cell proliferation and survival.
Menendez JA; Oza BP; Colomer R; Lupu R
Int J Oncol; 2005 Jun; 26(6):1507-15. PubMed ID: 15870863
[TBL] [Abstract][Full Text] [Related]
13. PKCdelta protects human breast tumor MCF-7 cells against tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis.
Zhang J; Liu N; Zhang J; Liu S; Liu Y; Zheng D
J Cell Biochem; 2005 Oct; 96(3):522-32. PubMed ID: 16114000
[TBL] [Abstract][Full Text] [Related]
14. Anti-gout agent allopurinol exerts cytotoxicity to human hormone-refractory prostate cancer cells in combination with tumor necrosis factor-related apoptosis-inducing ligand.
Yasuda T; Yoshida T; Goda AE; Horinaka M; Yano K; Shiraishi T; Wakada M; Mizutani Y; Miki T; Sakai T
Mol Cancer Res; 2008 Dec; 6(12):1852-60. PubMed ID: 19074830
[TBL] [Abstract][Full Text] [Related]
15. Cacalol, a natural sesquiterpene, induces apoptosis in breast cancer cells by modulating Akt-SREBP-FAS signaling pathway.
Liu W; Furuta E; Shindo K; Watabe M; Xing F; Pandey PR; Okuda H; Pai SK; Murphy LL; Cao D; Mo YY; Kobayashi A; Iiizumi M; Fukuda K; Xia B; Watabe K
Breast Cancer Res Treat; 2011 Jul; 128(1):57-68. PubMed ID: 20665104
[TBL] [Abstract][Full Text] [Related]
16. Malonyl-coenzyme-A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenografts.
Pizer ES; Thupari J; Han WF; Pinn ML; Chrest FJ; Frehywot GL; Townsend CA; Kuhajda FP
Cancer Res; 2000 Jan; 60(2):213-8. PubMed ID: 10667561
[TBL] [Abstract][Full Text] [Related]
17. Arsenic trioxide sensitizes human glioma cells, but not normal astrocytes, to TRAIL-induced apoptosis via CCAAT/enhancer-binding protein homologous protein-dependent DR5 up-regulation.
Kim EH; Yoon MJ; Kim SU; Kwon TK; Sohn S; Choi KS
Cancer Res; 2008 Jan; 68(1):266-75. PubMed ID: 18172319
[TBL] [Abstract][Full Text] [Related]
18. Malonyl-CoA decarboxylase inhibition is selectively cytotoxic to human breast cancer cells.
Zhou W; Tu Y; Simpson PJ; Kuhajda FP
Oncogene; 2009 Aug; 28(33):2979-87. PubMed ID: 19543323
[TBL] [Abstract][Full Text] [Related]
19. Specific resistance upon lentiviral TRAIL transfer by intracellular retention of TRAIL receptors.
Wenger T; Mattern J; Penzel R; Gassler N; Haas TL; Sprick MR; Walczak H; Krammer PH; Debatin KM; Herr I
Cell Death Differ; 2006 Oct; 13(10):1740-51. PubMed ID: 16470224
[TBL] [Abstract][Full Text] [Related]
20. CCAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction and ubiquitin/proteasome-mediated cellular FLICE-inhibitory protein down-regulation contribute to enhancement of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by dimethyl-celecoxib in human non small-cell lung cancer cells.
Chen S; Liu X; Yue P; Schönthal AH; Khuri FR; Sun SY
Mol Pharmacol; 2007 Nov; 72(5):1269-79. PubMed ID: 17684158
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]