338 related articles for article (PubMed ID: 16741519)
1. Intracellular TGF-beta receptor blockade abrogates Smad-dependent fibroblast activation in vitro and in vivo.
Ishida W; Mori Y; Lakos G; Sun L; Shan F; Bowes S; Josiah S; Lee WC; Singh J; Ling LE; Varga J
J Invest Dermatol; 2006 Aug; 126(8):1733-44. PubMed ID: 16741519
[TBL] [Abstract][Full Text] [Related]
2. Disruption of transforming growth factor beta signaling and profibrotic responses in normal skin fibroblasts by peroxisome proliferator-activated receptor gamma.
Ghosh AK; Bhattacharyya S; Lakos G; Chen SJ; Mori Y; Varga J
Arthritis Rheum; 2004 Apr; 50(4):1305-18. PubMed ID: 15077315
[TBL] [Abstract][Full Text] [Related]
3. Selective inhibition of activin receptor-like kinase 5 signaling blocks profibrotic transforming growth factor beta responses in skin fibroblasts.
Mori Y; Ishida W; Bhattacharyya S; Li Y; Platanias LC; Varga J
Arthritis Rheum; 2004 Dec; 50(12):4008-21. PubMed ID: 15593186
[TBL] [Abstract][Full Text] [Related]
4. Transforming growth factor (TGF)-β type I receptor kinase (ALK5) inhibitor alleviates profibrotic TGF-β1 responses in fibroblasts derived from Peyronie's plaque.
Piao S; Choi MJ; Tumurbaatar M; Kim WJ; Jin HR; Shin SH; Tuvshintur B; Yin GN; Song JS; Kwon MH; Lee SJ; Han JY; Kim SJ; Ryu JK; Suh JK
J Sex Med; 2010 Oct; 7(10):3385-95. PubMed ID: 20233292
[TBL] [Abstract][Full Text] [Related]
5. Expression and regulation of intracellular SMAD signaling in scleroderma skin fibroblasts.
Mori Y; Chen SJ; Varga J
Arthritis Rheum; 2003 Jul; 48(7):1964-78. PubMed ID: 12847691
[TBL] [Abstract][Full Text] [Related]
6. Sustained activation of fibroblast transforming growth factor-beta/Smad signaling in a murine model of scleroderma.
Takagawa S; Lakos G; Mori Y; Yamamoto T; Nishioka K; Varga J
J Invest Dermatol; 2003 Jul; 121(1):41-50. PubMed ID: 12839562
[TBL] [Abstract][Full Text] [Related]
7. Postnatal induction of transforming growth factor beta signaling in fibroblasts of mice recapitulates clinical, histologic, and biochemical features of scleroderma.
Sonnylal S; Denton CP; Zheng B; Keene DR; He R; Adams HP; Vanpelt CS; Geng YJ; Deng JM; Behringer RR; de Crombrugghe B
Arthritis Rheum; 2007 Jan; 56(1):334-44. PubMed ID: 17195237
[TBL] [Abstract][Full Text] [Related]
8. Macitentan inhibits the transforming growth factor-β profibrotic action, blocking the signaling mediated by the ETR/TβRI complex in systemic sclerosis dermal fibroblasts.
Cipriani P; Di Benedetto P; Ruscitti P; Verzella D; Fischietti M; Zazzeroni F; Liakouli V; Carubbi F; Berardicurti O; Alesse E; Giacomelli R
Arthritis Res Ther; 2015 Sep; 17(1):247. PubMed ID: 26357964
[TBL] [Abstract][Full Text] [Related]
9. Constitutively phosphorylated Smad3 interacts with Sp1 and p300 in scleroderma fibroblasts.
Ihn H; Yamane K; Asano Y; Jinnin M; Tamaki K
Rheumatology (Oxford); 2006 Feb; 45(2):157-65. PubMed ID: 16319104
[TBL] [Abstract][Full Text] [Related]
10. The antifibrotic effects of relaxin in human renal fibroblasts are mediated in part by inhibition of the Smad2 pathway.
Heeg MH; Koziolek MJ; Vasko R; Schaefer L; Sharma K; Müller GA; Strutz F
Kidney Int; 2005 Jul; 68(1):96-109. PubMed ID: 15954899
[TBL] [Abstract][Full Text] [Related]
11. cAMP inhibits transforming growth factor-beta-stimulated collagen synthesis via inhibition of extracellular signal-regulated kinase 1/2 and Smad signaling in cardiac fibroblasts.
Liu X; Sun SQ; Hassid A; Ostrom RS
Mol Pharmacol; 2006 Dec; 70(6):1992-2003. PubMed ID: 16959941
[TBL] [Abstract][Full Text] [Related]
12. Tribbles homologue 3 stimulates canonical TGF-β signalling to regulate fibroblast activation and tissue fibrosis.
Tomcik M; Palumbo-Zerr K; Zerr P; Sumova B; Avouac J; Dees C; Distler A; Becvar R; Distler O; Schett G; Senolt L; Distler JH
Ann Rheum Dis; 2016 Mar; 75(3):609-16. PubMed ID: 25603829
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of activin receptor-like kinase 5 attenuates bleomycin-induced pulmonary fibrosis.
Higashiyama H; Yoshimoto D; Kaise T; Matsubara S; Fujiwara M; Kikkawa H; Asano S; Kinoshita M
Exp Mol Pathol; 2007 Aug; 83(1):39-46. PubMed ID: 17274978
[TBL] [Abstract][Full Text] [Related]
14. Transforming growth factor-beta type 1 receptor (ALK5) and Smad proteins mediate TIMP-1 and collagen synthesis in experimental intestinal fibrosis.
Medina C; Santos-Martinez MJ; Santana A; Paz-Cabrera MC; Johnston MJ; Mourelle M; Salas A; Guarner F
J Pathol; 2011 Aug; 224(4):461-72. PubMed ID: 21465486
[TBL] [Abstract][Full Text] [Related]
15. Constitutive Smad signaling and Smad-dependent collagen gene expression in mouse embryonic fibroblasts lacking peroxisome proliferator-activated receptor-gamma.
Ghosh AK; Wei J; Wu M; Varga J
Biochem Biophys Res Commun; 2008 Sep; 374(2):231-6. PubMed ID: 18627765
[TBL] [Abstract][Full Text] [Related]
16. Silencing NLRC5 inhibits extracellular matrix expression in keloid fibroblasts via inhibition of transforming growth factor-β1/Smad signaling pathway.
Ma HL; Zhao XF; Chen GZ; Fang RH; Zhang FR
Biomed Pharmacother; 2016 Oct; 83():1016-1021. PubMed ID: 27525969
[TBL] [Abstract][Full Text] [Related]
17. Stimulation of the soluble guanylate cyclase (sGC) inhibits fibrosis by blocking non-canonical TGFβ signalling.
Beyer C; Zenzmaier C; Palumbo-Zerr K; Mancuso R; Distler A; Dees C; Zerr P; Huang J; Maier C; Pachowsky ML; Friebe A; Sandner P; Distler O; Schett G; Berger P; Distler JH
Ann Rheum Dis; 2015 Jul; 74(7):1408-16. PubMed ID: 24567525
[TBL] [Abstract][Full Text] [Related]
18. Transforming growth factor-beta receptor type I-dependent fibrogenic gene program is mediated via activation of Smad1 and ERK1/2 pathways.
Pannu J; Nakerakanti S; Smith E; ten Dijke P; Trojanowska M
J Biol Chem; 2007 Apr; 282(14):10405-13. PubMed ID: 17317656
[TBL] [Abstract][Full Text] [Related]
19. Human eosinophils have an intact Smad signaling pathway leading to a major transforming growth factor-beta target gene expression.
Kanzaki M; Shibagaki N; Hatsushika K; Mitsui H; Inozume T; Okamoto A; Dobashi Y; Ogawa H; Shimada S; Nakao A
Int Arch Allergy Immunol; 2007; 142(4):309-17. PubMed ID: 17135762
[TBL] [Abstract][Full Text] [Related]
20. Smad7 blocks transforming growth factor-β1-induced gingival fibroblast-myofibroblast transition via inhibitory regulation of Smad2 and connective tissue growth factor.
Sobral LM; Montan PF; Zecchin KG; Martelli-Junior H; Vargas PA; Graner E; Coletta RD
J Periodontol; 2011 Apr; 82(4):642-51. PubMed ID: 21054221
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
