398 related articles for article (PubMed ID: 16741655)
1. Saturable absorptive transport of the hydrophilic organic cation ranitidine in Caco-2 cells: role of pH-dependent organic cation uptake system and P-glycoprotein.
Bourdet DL; Thakker DR
Pharm Res; 2006 Jun; 23(6):1165-77. PubMed ID: 16741655
[TBL] [Abstract][Full Text] [Related]
2. Intestinal absorptive transport of the hydrophilic cation ranitidine: a kinetic modeling approach to elucidate the role of uptake and efflux transporters and paracellular vs. transcellular transport in Caco-2 cells.
Bourdet DL; Pollack GM; Thakker DR
Pharm Res; 2006 Jun; 23(6):1178-87. PubMed ID: 16741656
[TBL] [Abstract][Full Text] [Related]
3. Secretory transport of ranitidine and famotidine across Caco-2 cell monolayers.
Lee K; Ng C; Brouwer KL; Thakker DR
J Pharmacol Exp Ther; 2002 Nov; 303(2):574-80. PubMed ID: 12388638
[TBL] [Abstract][Full Text] [Related]
4. Apical uptake of organic cations by human intestinal Caco-2 cells: putative involvement of ASF transporters.
Martel F; Gründemann D; Calhau C; Schömig E
Naunyn Schmiedebergs Arch Pharmacol; 2001 Jan; 363(1):40-9. PubMed ID: 11191835
[TBL] [Abstract][Full Text] [Related]
5. Vectorial transport of fexofenadine across Caco-2 cells: involvement of apical uptake and basolateral efflux transporters.
Ming X; Knight BM; Thakker DR
Mol Pharm; 2011 Oct; 8(5):1677-86. PubMed ID: 21780830
[TBL] [Abstract][Full Text] [Related]
6. Modulation of the permeability of H2 receptor antagonists cimetidine and ranitidine by P-glycoprotein in rat intestine and the human colonic cell line Caco-2.
Collett A; Higgs NB; Sims E; Rowland M; Warhurst G
J Pharmacol Exp Ther; 1999 Jan; 288(1):171-8. PubMed ID: 9862768
[TBL] [Abstract][Full Text] [Related]
7. Carrier-mediated uptake of H2-receptor antagonists by the rat choroid plexus: involvement of rat organic anion transporter 3.
Nagata Y; Kusuhara H; Hirono S; Endou H; Sugiyama Y
Drug Metab Dispos; 2004 Sep; 32(9):1040-7. PubMed ID: 15319347
[TBL] [Abstract][Full Text] [Related]
8. Mechanisms underlying saturable intestinal absorption of metformin.
Proctor WR; Bourdet DL; Thakker DR
Drug Metab Dispos; 2008 Aug; 36(8):1650-8. PubMed ID: 18458049
[TBL] [Abstract][Full Text] [Related]
9. Characterization of the transport of the organic cation [3H]MPP+ in human intestinal epithelial (Caco-2) cells.
Martel F; Calhau C; Azevedo I
Naunyn Schmiedebergs Arch Pharmacol; 2000 May; 361(5):505-13. PubMed ID: 10832604
[TBL] [Abstract][Full Text] [Related]
10. Efflux ratio cannot assess P-glycoprotein-mediated attenuation of absorptive transport: asymmetric effect of P-glycoprotein on absorptive and secretory transport across Caco-2 cell monolayers.
Troutman MD; Thakker DR
Pharm Res; 2003 Aug; 20(8):1200-9. PubMed ID: 12948018
[TBL] [Abstract][Full Text] [Related]
11. The effect of polyoxyethylene polymers on the transport of ranitidine in Caco-2 cell monolayers.
Ashiru-Oredope DA; Patel N; Forbes B; Patel R; Basit AW
Int J Pharm; 2011 May; 409(1-2):164-8. PubMed ID: 21382460
[TBL] [Abstract][Full Text] [Related]
12. Saturable transport of H2-antagonists ranitidine and famotidine across Caco-2 cell monolayers.
Lee K; Thakker DR
J Pharm Sci; 1999 Jul; 88(7):680-7. PubMed ID: 10393565
[TBL] [Abstract][Full Text] [Related]
13. The H2 receptor antagonist nizatidine is a P-glycoprotein substrate: characterization of its intestinal epithelial cell efflux transport.
Dahan A; Sabit H; Amidon GL
AAPS J; 2009 Jun; 11(2):205-13. PubMed ID: 19319690
[TBL] [Abstract][Full Text] [Related]
14. Rhodamine 123 requires carrier-mediated influx for its activity as a P-glycoprotein substrate in Caco-2 cells.
Troutman MD; Thakker DR
Pharm Res; 2003 Aug; 20(8):1192-9. PubMed ID: 12948017
[TBL] [Abstract][Full Text] [Related]
15. Caco-2 versus Caco-2/HT29-MTX co-cultured cell lines: permeabilities via diffusion, inside- and outside-directed carrier-mediated transport.
Hilgendorf C; Spahn-Langguth H; Regårdh CG; Lipka E; Amidon GL; Langguth P
J Pharm Sci; 2000 Jan; 89(1):63-75. PubMed ID: 10664539
[TBL] [Abstract][Full Text] [Related]
16. Functional characterization of peptide transporters in MDCKII-MDR1 cell line as a model for oral absorption studies.
Agarwal S; Jain R; Pal D; Mitra AK
Int J Pharm; 2007 Mar; 332(1-2):147-52. PubMed ID: 17097248
[TBL] [Abstract][Full Text] [Related]
17. Vectorial transport of the plant alkaloid berberine by double-transfected cells expressing the human organic cation transporter 1 (OCT1, SLC22A1) and the efflux pump MDR1 P-glycoprotein (ABCB1).
Nies AT; Herrmann E; Brom M; Keppler D
Naunyn Schmiedebergs Arch Pharmacol; 2008 Feb; 376(6):449-61. PubMed ID: 18157518
[TBL] [Abstract][Full Text] [Related]
18. Multiple efflux pumps are involved in the transepithelial transport of colchicine: combined effect of p-glycoprotein and multidrug resistance-associated protein 2 leads to decreased intestinal absorption throughout the entire small intestine.
Dahan A; Sabit H; Amidon GL
Drug Metab Dispos; 2009 Oct; 37(10):2028-36. PubMed ID: 19589874
[TBL] [Abstract][Full Text] [Related]
19. Photoaffinity labeling of the anionic sites in Caco-2 cells mediating saturable transport of hydrophilic cations ranitidine and famotidine.
Bourdet DL; Lee K; Thakker DR
J Med Chem; 2004 May; 47(11):2935-8. PubMed ID: 15139772
[TBL] [Abstract][Full Text] [Related]
20. Atorvastatin transport in the Caco-2 cell model: contributions of P-glycoprotein and the proton-monocarboxylic acid co-transporter.
Wu X; Whitfield LR; Stewart BH
Pharm Res; 2000 Feb; 17(2):209-15. PubMed ID: 10751037
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]