127 related articles for article (PubMed ID: 1674542)
1. The agonist pharmacophore of the benzodiazepine receptor. Synthesis of a selective anticonvulsant/anxiolytic.
Diaz-Arauzo H; Evoniuk GE; Skolnick P; Cook JM
J Med Chem; 1991 May; 34(5):1754-6. PubMed ID: 1674542
[No Abstract] [Full Text] [Related]
2. Synthesis and evaluation of analogues of the partial agonist 6-(propyloxy)-4-(methoxymethyl)-beta-carboline-3-carboxylic acid ethyl ester (6-PBC) and the full agonist 6-(benzyloxy)-4-(methoxymethyl)-beta-carboline-3-carboxylic acid ethyl ester (Zk 93423) at wild type and recombinant GABAA receptors.
Cox ED; Diaz-Arauzo H; Huang Q; Reddy MS; Ma C; Harris B; McKernan R; Skolnick P; Cook JM
J Med Chem; 1998 Jul; 41(14):2537-52. PubMed ID: 9651158
[TBL] [Abstract][Full Text] [Related]
3. Structural requirements for agonist actions at the benzodiazepine receptor: studies with analogues of 6-(benzyloxy)-4-(methoxymethyl)-beta-carboline-3-carboxylic acid ethyl ester.
Hollinshead SP; Trudell ML; Skolnick P; Cook JM
J Med Chem; 1990 Mar; 33(3):1062-9. PubMed ID: 1968513
[TBL] [Abstract][Full Text] [Related]
4. Pharmacokinetics, anticonvulsant efficacy and adverse effects of the beta-carboline abecarnil, a novel ligand for benzodiazepine receptors, after acute and chronic administration in dogs.
Löscher W; Hönack D; Scherkl R; Hashem A; Frey HH
J Pharmacol Exp Ther; 1990 Nov; 255(2):541-8. PubMed ID: 1978730
[TBL] [Abstract][Full Text] [Related]
5. [Esters of beta-carboline-3-carboxylic acids with alicyclic alcohols--synthesis and benzodiazepine receptor affinity].
Geldsetzer KH; Schunack W
Arch Pharm (Weinheim); 1990 Jan; 323(1):9-12. PubMed ID: 1970720
[TBL] [Abstract][Full Text] [Related]
6. Pharmacological evidence for full agonist activity of abecarnil at certain GABAA receptors.
Serra M; Ghiani CA; Motzo C; Biggio G
Psychopharmacol Ser; 1993; 11():62-78. PubMed ID: 7908434
[No Abstract] [Full Text] [Related]
7. 3-Heteroaryl-2-pyridones: benzodiazepine site ligands with functional delectivity for alpha 2/alpha 3-subtypes of human GABA(A) receptor-ion channels.
Collins I; Moyes C; Davey WB; Rowley M; Bromidge FA; Quirk K; Atack JR; McKernan RM; Thompson SA; Wafford K; Dawson GR; Pike A; Sohal B; Tsou NN; Ball RG; Castro JL
J Med Chem; 2002 Apr; 45(9):1887-900. PubMed ID: 11960500
[TBL] [Abstract][Full Text] [Related]
8. A search for a new anticonvulsant and anxiolytic benzodiazepine devoid of side effects and tolerance liability.
Costa E; Auta J; Caruncho H; Guidotti A; Impagnatiello F; Pesold C; Thompson DM
Adv Biochem Psychopharmacol; 1995; 48():75-92. PubMed ID: 7653327
[No Abstract] [Full Text] [Related]
9. Pharmacology of gamma-aminobutyric acidA receptor complex after the in vivo administration of the anxioselective and anticonvulsant beta-carboline derivative abecarnil.
Serra M; Foddi MC; Ghiani CA; Melis MA; Motzo C; Concas A; Sanna E; Biggio G
J Pharmacol Exp Ther; 1992 Dec; 263(3):1360-8. PubMed ID: 1361574
[TBL] [Abstract][Full Text] [Related]
10. Abecarnil: a novel anxiolytic with mixed full agonist/partial agonist properties in animal models of anxiety and sedation.
Stephens DN; Turski L; Jones GH; Steppuhn KG; Schneider HH
Psychopharmacol Ser; 1993; 11():79-95. PubMed ID: 7908435
[No Abstract] [Full Text] [Related]
11. A novel selective GABA(A) alpha1 receptor agonist displaying sedative and anxiolytic-like properties in rodents.
Selleri S; Bruni F; Costagli C; Costanzo A; Guerrini G; Ciciani G; Gratteri P; Besnard F; Costa B; Montali M; Martini C; Fohlin J; De Siena G; Aiello PM
J Med Chem; 2005 Oct; 48(21):6756-60. PubMed ID: 16220991
[TBL] [Abstract][Full Text] [Related]
12. Synthesis of benzo-fused benzodiazepines employed as probes of the agonist pharmacophore of benzodiazepine receptors.
Zhang W; Koehler KF; Harris B; Skolnick P; Cook JM
J Med Chem; 1994 Mar; 37(6):745-57. PubMed ID: 8145224
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and pharmacological screening of derivatives of isoxazolo[4, 3-d]pyridimidine.I.
Poreba K; Wagner E; Jakowicz I; Balika D
Farmaco; 1994; 49(7-8):529-32. PubMed ID: 7945722
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and benzodiazepine receptor affinity of pyrazolo[1,5-a]pyrimidine derivatives. 3. New 6-(3-thienyl) series as alpha 1 selective ligands.
Selleri S; Bruni F; Costagli C; Costanzo A; Guerrini G; Ciciani G; Gratteri P; Bonaccini C; Malmberg Aiello P; Besnard F; Renard S; Costa B; Martini C
J Med Chem; 2003 Jan; 46(2):310-3. PubMed ID: 12519068
[TBL] [Abstract][Full Text] [Related]
15. Beta-carbolines: synthesis and neurochemical and pharmacological actions on brain benzodiazepine receptors.
Cain M; Weber RW; Guzman F; Cook JM; Barker SA; Rice KC; Crawley JN; Paul SM; Skolnick P
J Med Chem; 1982 Sep; 25(9):1081-91. PubMed ID: 6127411
[TBL] [Abstract][Full Text] [Related]
16. [Anxiolytic action of beta-carbolines in rats].
Burov IuV; Orekhov SN; Vedernikova NN
Biull Eksp Biol Med; 1985 Apr; 99(4):453-5. PubMed ID: 2859060
[TBL] [Abstract][Full Text] [Related]
17. Benzodiazepine receptor ligands. 4. Synthesis and pharmacological evaluation of 3-heteroaryl-8-chloropyrazolo[5,1-c][1,2,4] benzotriazine 5-oxides.
Costanzo A; Guerrini G; Ciciani G; Bruni F; Selleri S; Costa B; Martini C; Lucacchini A; Aiello PM; Ipponi A
J Med Chem; 1999 Jun; 42(12):2218-26. PubMed ID: 10377227
[TBL] [Abstract][Full Text] [Related]
18. Ethological pharmacology of anxiogenic and anxiolytic drugs.
Poshivalov VP; Suchotina IA; Verbitzkaya EV
Ann Ist Super Sanita; 1988; 24(3):453-9. PubMed ID: 2903710
[No Abstract] [Full Text] [Related]
19. Synthesis and anticonvulsant activity of N-3 substituted 2,3-benzodiazepines.
Quartarone S; Caruso R; Orlando V; Russo E; De Sarro G; Chimirri A
Farmaco; 2004 May; 59(5):353-8. PubMed ID: 15120314
[TBL] [Abstract][Full Text] [Related]
20. Evidence for the pharmacological relevance of benzodiazepine receptors to anticonvulsant activity.
Fisher TE; Johnson DD; Tuchek JM; Crawford RD
Can J Physiol Pharmacol; 1985 Nov; 63(11):1477-9. PubMed ID: 2866832
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
