BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

120 related articles for article (PubMed ID: 1674871)

  • 1. Effect of the calmodulin inhibitor trifluoperazine on phosphorylation of P-glycoprotein and topoisomerase II: relationship to modulation of subcellular distribution, DNA damage and cytotoxicity of doxorubicin in multidrug resistant L1210 mouse leukemia cells.
    Ganapathi R; Kamath N; Constantinou A; Grabowski D; Ford J; Anderson A
    Biochem Pharmacol; 1991 Jun; 41(12):R21-6. PubMed ID: 1674871
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Calmodulin inhibitor trifluoperazine in combination with doxorubicin induces the selection of tumour cells with the multidrug resistant phenotype.
    Kamath N; Grabowski D; Ford J; Ganapathi R
    Br J Cancer; 1993 Jun; 67(6):1203-8. PubMed ID: 8099806
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Trifluoperazine modulation of resistance to the topoisomerase II inhibitor etoposide in doxorubicin resistant L1210 murine leukemia cells.
    Kamath N; Grabowski D; Ford J; Drake F; Kerrigan D; Pommier Y; Ganapathi R
    Cancer Commun; 1991 Feb; 3(2):37-44. PubMed ID: 1995027
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential effect of the calmodulin inhibitor trifluoperazine in modulating cellular accumulation, retention and cytotoxicity of doxorubicin in progressively doxorubicin-resistant L1210 mouse leukemia cells. Lack of correlation between cellular doxorubicin levels and expression of resistance.
    Ganapathi R; Grabowski D
    Biochem Pharmacol; 1988 Jan; 37(2):185-93. PubMed ID: 3342075
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Overexpression of P-glycoprotein and alterations in topoisomerase II in P388 mouse leukemia cells selected in vivo for resistance to mitoxantrone.
    Kamath N; Grabowski D; Ford J; Kerrigan D; Pommier Y; Ganapathi R
    Biochem Pharmacol; 1992 Sep; 44(5):937-45. PubMed ID: 1356339
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Relationship between expression of P-glycoprotein and efficacy of trifluoperazine in multidrug-resistant cells.
    Ganapathi R; Kuo T; Teeter L; Grabowski D; Ford J
    Mol Pharmacol; 1991 Jan; 39(1):1-8. PubMed ID: 1670962
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Modulation of doxorubicin-induced chromosomal damage by calmodulin inhibitors and its relationship to cytotoxicity in progressively doxorubicin-resistant tumor cells.
    Ganapathi R; Grabowski D; Hoeltge G; Neelon R
    Biochem Pharmacol; 1990 Oct; 40(7):1657-62. PubMed ID: 2222519
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Progressive resistance to doxorubicin in mouse leukemia L1210 cells with multidrug resistance phenotype: reductions in drug-induced topoisomerase II-mediated DNA cleavage.
    Ganapathi R; Grabowski D; Ford J; Heiss C; Kerrigan D; Pommier Y
    Cancer Commun; 1989; 1(4):217-24. PubMed ID: 2576973
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modulation in vitro and in vivo of cytotoxicity but not cellular levels of doxorubicin by the calmodulin inhibitor trifluoperazine is dependent on the level of resistance.
    Ganapathi R; Schmidt H; Grabowski D; Melia M; Ratliff N
    Br J Cancer; 1988 Sep; 58(3):335-40. PubMed ID: 3179186
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Factors governing the modulation of vinca-alkaloid resistance in doxorubicin-resistant cells by the calmodulin inhibitor trifluoperazine.
    Ganapathi R; Grabowski D; Schmidt H
    Biochem Pharmacol; 1986 Feb; 35(4):673-8. PubMed ID: 3947398
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cellular events involved in the sensitization of etoposide-resistant cells by inhibitors of calcium-calmodulin-dependent processes. Role for effects on apoptosis, DNA cleavable complex, and phosphorylation.
    Kawamura K; Grabowski D; Krivacic K; Hidaka H; Ganapathi R
    Biochem Pharmacol; 1996 Dec; 52(12):1903-9. PubMed ID: 8951349
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential effect of the calmodulin inhibitor trifluoperazine on cellular accumulation, retention, and cytotoxicity of anthracyclines in doxorubicin (adriamycin)-resistant P388 mouse leukemia cells.
    Ganapathi R; Grabowski D; Rouse W; Riegler F
    Cancer Res; 1984 Nov; 44(11):5056-61. PubMed ID: 6488165
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Reversal of etoposide resistance in non-P-glycoprotein expressing multidrug resistant tumor cell lines by novobiocin.
    Rappa G; Lorico A; Sartorelli AC
    Cancer Res; 1993 Nov; 53(22):5487-93. PubMed ID: 8106148
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Anthracycline-induced DNA breaks and resealing in doxorubicin-resistant murine leukemic P388 cells.
    Maniar N; Krishan A; Israel M; Samy TS
    Biochem Pharmacol; 1988 May; 37(9):1763-72. PubMed ID: 2837239
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Different modes of anthracycline interaction with topoisomerase II. Separate structures critical for DNA-cleavage, and for overcoming topoisomerase II-related drug resistance.
    Jensen PB; Sørensen BS; Sehested M; Demant EJ; Kjeldsen E; Friche E; Hansen HH
    Biochem Pharmacol; 1993 May; 45(10):2025-35. PubMed ID: 8390259
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Topoisomerase II-mediated DNA damage produced by 4'-(9-acridinylamino)methanesulfon-m-anisidide and related acridines in L1210 cells and isolated nuclei: relation to cytotoxicity.
    Covey JM; Kohn KW; Kerrigan D; Tilchen EJ; Pommier Y
    Cancer Res; 1988 Feb; 48(4):860-5. PubMed ID: 2827887
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cellular and karyotypic characterization of two doxorubicin resistant cell lines isolated from the same parental human leukemia cell line.
    Zalcberg JR; Hu XF; Wall DM; Mirski S; Cole S; Nadalin G; De Luise M; Parkin JD; Vrazas V; Campbell L
    Int J Cancer; 1994 May; 57(4):522-8. PubMed ID: 7514153
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential single- versus double-strand DNA breakage produced by doxorubicin and its morpholinyl analogues.
    Duran GE; Lau DH; Lewis AD; Kühl JS; Bämmler TK; Sikic BI
    Cancer Chemother Pharmacol; 1996; 38(3):210-6. PubMed ID: 8646794
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Induced multidrug resistance in murine leukemia L1210 and associated changes in a surface-membrane glycoprotein.
    Volm M; Bak M; Efferth T; Mattern J
    J Cancer Res Clin Oncol; 1989; 115(1):17-24. PubMed ID: 2563999
    [TBL] [Abstract][Full Text] [Related]  

  • 20. N-benzyladriamycin-14-valerate versus progressively doxorubicin-resistant murine tumours: cellular pharmacology and characterisation of cross-resistance in vitro and in vivo.
    Ganapathi R; Grabowski D; Sweatman TW; Seshadri R; Israel M
    Br J Cancer; 1989 Dec; 60(6):819-26. PubMed ID: 2605093
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.