BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

529 related articles for article (PubMed ID: 16751189)

  • 1. Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction.
    Qin W; Yang T; Ho L; Zhao Z; Wang J; Chen L; Zhao W; Thiyagarajan M; MacGrogan D; Rodgers JT; Puigserver P; Sadoshima J; Deng H; Pedrini S; Gandy S; Sauve AA; Pasinetti GM
    J Biol Chem; 2006 Aug; 281(31):21745-21754. PubMed ID: 16751189
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Calorie restriction attenuates Alzheimer's disease type brain amyloidosis in Squirrel monkeys (Saimiri sciureus).
    Qin W; Chachich M; Lane M; Roth G; Bryant M; de Cabo R; Ottinger MA; Mattison J; Ingram D; Gandy S; Pasinetti GM
    J Alzheimers Dis; 2006 Dec; 10(4):417-22. PubMed ID: 17183154
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Caloric restriction attenuates beta-amyloid neuropathology in a mouse model of Alzheimer's disease.
    Wang J; Ho L; Qin W; Rocher AB; Seror I; Humala N; Maniar K; Dolios G; Wang R; Hof PR; Pasinetti GM
    FASEB J; 2005 Apr; 19(6):659-61. PubMed ID: 15650008
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Connective tissue growth factor (CTGF) expression in the brain is a downstream effector of insulin resistance- associated promotion of Alzheimer's disease beta-amyloid neuropathology.
    Zhao Z; Ho L; Wang J; Qin W; Festa ED; Mobbs C; Hof P; Rocher A; Masur S; Haroutunian V; Pasinetti GM
    FASEB J; 2005 Dec; 19(14):2081-2. PubMed ID: 16186174
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of forkhead transcription factor FoxO3a contributes to calorie restriction-induced prevention of Alzheimer's disease-type amyloid neuropathology and spatial memory deterioration.
    Qin W; Zhao W; Ho L; Wang J; Walsh K; Gandy S; Pasinetti GM
    Ann N Y Acad Sci; 2008 Dec; 1147():335-47. PubMed ID: 19076455
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The sirtuin pathway in ageing and Alzheimer disease: mechanistic and therapeutic considerations.
    Bonda DJ; Lee HG; Camins A; Pallàs M; Casadesus G; Smith MA; Zhu X
    Lancet Neurol; 2011 Mar; 10(3):275-9. PubMed ID: 21349442
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease.
    Ho L; Qin W; Pompl PN; Xiang Z; Wang J; Zhao Z; Peng Y; Cambareri G; Rocher A; Mobbs CV; Hof PR; Pasinetti GM
    FASEB J; 2004 May; 18(7):902-4. PubMed ID: 15033922
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Reduction of β-amyloid and γ-secretase by calorie restriction in female Tg2576 mice.
    Schafer MJ; Alldred MJ; Lee SH; Calhoun ME; Petkova E; Mathews PM; Ginsberg SD
    Neurobiol Aging; 2015 Mar; 36(3):1293-302. PubMed ID: 25556162
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A disintegrin-metalloproteinase prevents amyloid plaque formation and hippocampal defects in an Alzheimer disease mouse model.
    Postina R; Schroeder A; Dewachter I; Bohl J; Schmitt U; Kojro E; Prinzen C; Endres K; Hiemke C; Blessing M; Flamez P; Dequenne A; Godaux E; van Leuven F; Fahrenholz F
    J Clin Invest; 2004 May; 113(10):1456-64. PubMed ID: 15146243
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
    Evin G; Zhu A; Holsinger RM; Masters CL; Li QX
    J Neurosci Res; 2003 Nov; 74(3):386-92. PubMed ID: 14598315
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Different Expression Patterns of Amyloid-β Protein Precursor Secretases in Human and Mouse Hippocampal Neurons: A Potential Contribution to Species Differences in Neuronal Susceptibility to Amyloid-β Pathogenesis.
    Xu ZQ; Huang H; Chen YL; Gao YY; Xu J; Marshall C; Cai ZY; Xiao M
    J Alzheimers Dis; 2016; 51(1):179-95. PubMed ID: 26836155
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.
    Natunen T; Takalo M; Kemppainen S; Leskelä S; Marttinen M; Kurkinen KMA; Pursiheimo JP; Sarajärvi T; Viswanathan J; Gabbouj S; Solje E; Tahvanainen E; Pirttimäki T; Kurki M; Paananen J; Rauramaa T; Miettinen P; Mäkinen P; Leinonen V; Soininen H; Airenne K; Tanzi RE; Tanila H; Haapasalo A; Hiltunen M
    Neurobiol Dis; 2016 Jan; 85():187-205. PubMed ID: 26563932
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The role of Sirt1: at the crossroad between promotion of longevity and protection against Alzheimer's disease neuropathology.
    Wang J; Fivecoat H; Ho L; Pan Y; Ling E; Pasinetti GM
    Biochim Biophys Acta; 2010 Aug; 1804(8):1690-4. PubMed ID: 19945548
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis of allosteric peptide activator for human SIRT1 and its biological evaluation in cellular model of Alzheimer's disease.
    Kumar R; Nigam L; Singh AP; Singh K; Subbarao N; Dey S
    Eur J Med Chem; 2017 Feb; 127():909-916. PubMed ID: 27836195
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Neuronal deficiency of presenilin 1 inhibits amyloid plaque formation and corrects hippocampal long-term potentiation but not a cognitive defect of amyloid precursor protein [V717I] transgenic mice.
    Dewachter I; Reversé D; Caluwaerts N; Ris L; Kuipéri C; Van den Haute C; Spittaels K; Umans L; Serneels L; Thiry E; Moechars D; Mercken M; Godaux E; Van Leuven F
    J Neurosci; 2002 May; 22(9):3445-53. PubMed ID: 11978821
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo.
    Smith JJ; Kenney RD; Gagne DJ; Frushour BP; Ladd W; Galonek HL; Israelian K; Song J; Razvadauskaite G; Lynch AV; Carney DP; Johnson RJ; Lavu S; Iffland A; Elliott PJ; Lambert PD; Elliston KO; Jirousek MR; Milne JC; Boss O
    BMC Syst Biol; 2009 Mar; 3():31. PubMed ID: 19284563
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Astrocytes infected with Chlamydia pneumoniae demonstrate altered expression and activity of secretases involved in the generation of β-amyloid found in Alzheimer disease.
    Al-Atrache Z; Lopez DB; Hingley ST; Appelt DM
    BMC Neurosci; 2019 Feb; 20(1):6. PubMed ID: 30786875
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel osmotin inhibits SREBP2 via the AdipoR1/AMPK/SIRT1 pathway to improve Alzheimer's disease neuropathological deficits.
    Shah SA; Yoon GH; Chung SS; Abid MN; Kim TH; Lee HY; Kim MO
    Mol Psychiatry; 2017 Mar; 22(3):407-416. PubMed ID: 27001618
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cerebrolysin decreases amyloid-beta production by regulating amyloid protein precursor maturation in a transgenic model of Alzheimer's disease.
    Rockenstein E; Torrance M; Mante M; Adame A; Paulino A; Rose JB; Crews L; Moessler H; Masliah E
    J Neurosci Res; 2006 May; 83(7):1252-61. PubMed ID: 16511867
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The role of calorie restriction and SIRT1 in prion-mediated neurodegeneration.
    Chen D; Steele AD; Hutter G; Bruno J; Govindarajan A; Easlon E; Lin SJ; Aguzzi A; Lindquist S; Guarente L
    Exp Gerontol; 2008 Dec; 43(12):1086-93. PubMed ID: 18799131
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 27.