BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 16753577)

  • 1. Genipin inhibits UCP2-mediated proton leak and acutely reverses obesity- and high glucose-induced beta cell dysfunction in isolated pancreatic islets.
    Zhang CY; Parton LE; Ye CP; Krauss S; Shen R; Lin CT; Porco JA; Lowell BB
    Cell Metab; 2006 Jun; 3(6):417-27. PubMed ID: 16753577
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A radical explanation for glucose-induced beta cell dysfunction.
    Brownlee M
    J Clin Invest; 2003 Dec; 112(12):1788-90. PubMed ID: 14679173
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Uncoupling protein 2 and aldolase B impact insulin release by modulating mitochondrial function and Ca
    Inoue R; Tsuno T; Togashi Y; Okuyama T; Sato A; Nishiyama K; Kyohara M; Li J; Fukushima S; Kin T; Miyashita D; Shiba Y; Atobe Y; Kiyonari H; Bando K; Shapiro AMJ; Funakoshi K; Kulkarni RN; Terauchi Y; Shirakawa J
    iScience; 2022 Jul; 25(7):104603. PubMed ID: 35800776
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Catalpolaglycone disrupts mitochondrial thermogenesis by specifically binding to a conserved lysine residue of UCP2 on the proton leak tunnel.
    Shen F; Yang W; Luan G; Peng J; Li Z; Gao J; Hou Y; Bai G
    Phytomedicine; 2024 Mar; 125():155356. PubMed ID: 38241920
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Genipin-induced inhibition of uncoupling protein-2 sensitizes drug-resistant cancer cells to cytotoxic agents.
    Mailloux RJ; Adjeitey CN; Harper ME
    PLoS One; 2010 Oct; 5(10):e13289. PubMed ID: 20967268
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity.
    Parton LE; Ye CP; Coppari R; Enriori PJ; Choi B; Zhang CY; Xu C; Vianna CR; Balthasar N; Lee CE; Elmquist JK; Cowley MA; Lowell BB
    Nature; 2007 Sep; 449(7159):228-32. PubMed ID: 17728716
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 'Genipin' - the natural water soluble cross-linking agent and its importance in the modified drug delivery systems: an overview.
    Manickam B; Sreedharan R; Elumalai M
    Curr Drug Deliv; 2014; 11(1):139-45. PubMed ID: 24041312
    [TBL] [Abstract][Full Text] [Related]  

  • 8. UCP2 transports C4 metabolites out of mitochondria, regulating glucose and glutamine oxidation.
    Vozza A; Parisi G; De Leonardis F; Lasorsa FM; Castegna A; Amorese D; Marmo R; Calcagnile VM; Palmieri L; Ricquier D; Paradies E; Scarcia P; Palmieri F; Bouillaud F; Fiermonte G
    Proc Natl Acad Sci U S A; 2014 Jan; 111(3):960-5. PubMed ID: 24395786
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cellular model of Warburg effect identifies tumor promoting function of UCP2 in breast cancer and its suppression by genipin.
    Ayyasamy V; Owens KM; Desouki MM; Liang P; Bakin A; Thangaraj K; Buchsbaum DJ; LoBuglio AF; Singh KK
    PLoS One; 2011; 6(9):e24792. PubMed ID: 21935467
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The role of uncoupling protein 2 (UCP2) on the development of type 2 diabetes mellitus and its chronic complications.
    Souza BM; Assmann TS; Kliemann LM; Gross JL; Canani LH; Crispim D
    Arq Bras Endocrinol Metabol; 2011 Jun; 55(4):239-48. PubMed ID: 21779625
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of Uncoupling Protein 2 Enhances the Radiosensitivity of Cervical Cancer Cells by Promoting the Production of Reactive Oxygen Species.
    Liu CH; Huang ZH; Dong XY; Zhang XQ; Li YH; Zhao G; Sun BS; Shen YN
    Oxid Med Cell Longev; 2020; 2020():5135893. PubMed ID: 32190174
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Genipin Reverses HFD-Induced Liver Damage and Inhibits UCP2-Mediated Pyroptosis in Mice.
    Zhong H; Liu M; Ji Y; Ma M; Chen K; Liang T; Liu C
    Cell Physiol Biochem; 2018; 49(5):1885-1897. PubMed ID: 30235442
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Genipin, an Inhibitor of UCP2 as a Promising New Anticancer Agent: A Review of the Literature.
    Cho YS
    Int J Mol Sci; 2022 May; 23(10):. PubMed ID: 35628447
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Continued clearance of apoptotic cells critically depends on the phagocyte Ucp2 protein.
    Park D; Han CZ; Elliott MR; Kinchen JM; Trampont PC; Das S; Collins S; Lysiak JJ; Hoehn KL; Ravichandran KS
    Nature; 2011 Aug; 477(7363):220-4. PubMed ID: 21857682
    [TBL] [Abstract][Full Text] [Related]  

  • 15. UCP2 and pancreatic cancer: conscious uncoupling for therapeutic effect.
    Caggiano EG; Taniguchi CM
    Cancer Metastasis Rev; 2024 Jan; ():. PubMed ID: 38194152
    [TBL] [Abstract][Full Text] [Related]  

  • 16. UCP2-SIRT3 Signaling Relieved Hyperglycemia-Induced Oxidative Stress and Senescence in Diabetic Retinopathy.
    Li S; Sun D; Chen S; Zhang S; Gu Q; Shen Y; Xu L; Xu X; Wei F; Wang N
    Invest Ophthalmol Vis Sci; 2024 Jan; 65(1):14. PubMed ID: 38175638
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of pyroptosis and apoptosis by capsaicin protects against LPS-induced acute kidney injury through TRPV1/UCP2 axis
    Han J; Wu J; Liu H; Huang Y; Ju W; Xing Y; Zhang X; Yang J
    Open Life Sci; 2023; 18(1):20220647. PubMed ID: 37528882
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Genipin Crosslinks the Extracellular Matrix to Rescue Developmental and Degenerative Defects, and Accelerates Regeneration of Peripheral Neurons.
    Saito-Diaz K; Dietrich P; Wu HF; Sun X; Patel AJ; Wzientek CG; Prudden AR; Boons GJ; Chen S; Studer L; Xu B; Dragatsis I; Zeltner N
    bioRxiv; 2023 Mar; ():. PubMed ID: 36993570
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of Mitochondrial Uncoupling Proteins Arrests Human Spermatozoa Motility without Compromising Viability.
    Carrageta DF; Freire-Brito L; Guerra-Carvalho B; Ribeiro JC; Monteiro BS; Barros A; Oliveira PF; Monteiro MP; Alves MG
    Antioxidants (Basel); 2023 Feb; 12(2):. PubMed ID: 36829970
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of Genipin as a Potential Treatment for Type 2 Diabetes.
    Wu Y; Wang Y; Liu D
    Int J Mol Sci; 2023 Jan; 24(3):. PubMed ID: 36768454
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.