These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

181 related articles for article (PubMed ID: 16754541)

  • 1. Metabolism and tissue distribution of orally administered trichloroethylene in male and female rats: identification of glutathione- and cytochrome P-450-derived metabolites in liver, kidney, blood, and urine.
    Lash LH; Putt DA; Parker JC
    J Toxicol Environ Health A; 2006 Jul; 69(13):1285-309. PubMed ID: 16754541
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Glutathione-dependent metabolism of trichloroethylene in isolated liver and kidney cells of rats and its role in mitochondrial and cellular toxicity.
    Lash LH; Xu Y; Elfarra AA; Duescher RJ; Parker JC
    Drug Metab Dispos; 1995 Aug; 23(8):846-53. PubMed ID: 7493552
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of S-(1,2-dichlorovinyl)glutathione in the blood of human volunteers exposed to trichloroethylene.
    Lash LH; Putt DA; Brashear WT; Abbas R; Parker JC; Fisher JW
    J Toxicol Environ Health A; 1999 Jan; 56(1):1-21. PubMed ID: 9923751
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Glutathione conjugation of trichloroethylene in rats and mice: sex-, species-, and tissue-dependent differences.
    Lash LH; Qian W; Putt DA; Jacobs K; Elfarra AA; Krause RJ; Parker JC
    Drug Metab Dispos; 1998 Jan; 26(1):12-9. PubMed ID: 9443846
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Biotransformation of trichloroethene: dose-dependent excretion of 2,2,2-trichloro-metabolites and mercapturic acids in rats and humans after inhalation.
    Bernauer U; Birner G; Dekant W; Henschler D
    Arch Toxicol; 1996; 70(6):338-46. PubMed ID: 8975632
    [TBL] [Abstract][Full Text] [Related]  

  • 6. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
    Beland FA
    Toxic Rep Ser; 1999 Aug; (59):1-66, A1-E7. PubMed ID: 11803702
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Study on the cytochrome P-450- and glutathione-dependent biotransformation of trichloroethylene in humans.
    Bloemen LJ; Monster AC; Kezic S; Commandeur JN; Veulemans H; Vermeulen NP; Wilmer JW
    Int Arch Occup Environ Health; 2001 Mar; 74(2):102-8. PubMed ID: 11317702
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Metabolism and toxicity of trichloroethylene and S-(1,2-dichlorovinyl)-L-cysteine in freshly isolated human proximal tubular cells.
    Cummings BS; Lash LH
    Toxicol Sci; 2000 Feb; 53(2):458-66. PubMed ID: 10696794
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Role of cytochrome P450 and glutathione S-transferase alpha in the metabolism and cytotoxicity of trichloroethylene in rat kidney.
    Cummings BS; Parker JC; Lash LH
    Biochem Pharmacol; 2000 Mar; 59(5):531-43. PubMed ID: 10660119
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Renal and hepatic toxicity of trichloroethylene and its glutathione-derived metabolites in rats and mice: sex-, species-, and tissue-dependent differences.
    Lash LH; Qian W; Putt DA; Hueni SE; Elfarra AA; Krause RJ; Parker JC
    J Pharmacol Exp Ther; 2001 Apr; 297(1):155-64. PubMed ID: 11259540
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A human physiologically based pharmacokinetic model for trichloroethylene and its metabolites, trichloroacetic acid and free trichloroethanol.
    Fisher JW; Mahle D; Abbas R
    Toxicol Appl Pharmacol; 1998 Oct; 152(2):339-59. PubMed ID: 9853003
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Glutathione conjugation of trichloroethylene in human liver and kidney: kinetics and individual variation.
    Lash LH; Lipscomb JC; Putt DA; Parker JC
    Drug Metab Dispos; 1999 Mar; 27(3):351-9. PubMed ID: 10064565
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Species- and sex-related differences in metabolism of trichloroethylene to yield chloral and trichloroethanol in mouse, rat, and human liver microsomes.
    Elfarra AA; Krause RJ; Last AR; Lash LH; Parker JC
    Drug Metab Dispos; 1998 Aug; 26(8):779-85. PubMed ID: 9698293
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A physiologically based pharmacokinetic model for trichloroethylene and its metabolites, chloral hydrate, trichloroacetate, dichloroacetate, trichloroethanol, and trichloroethanol glucuronide in B6C3F1 mice.
    Abbas R; Fisher JW
    Toxicol Appl Pharmacol; 1997 Nov; 147(1):15-30. PubMed ID: 9356303
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Consideration of the target organ toxicity of trichloroethylene in terms of metabolite toxicity and pharmacokinetics.
    Davidson IW; Beliles RP
    Drug Metab Rev; 1991; 23(5-6):493-599. PubMed ID: 1802654
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Comparative analysis of the relationship between trichloroethylene metabolism and tissue-specific toxicity among inbred mouse strains: liver effects.
    Yoo HS; Bradford BU; Kosyk O; Shymonyak S; Uehara T; Collins LB; Bodnar WM; Ball LM; Gold A; Rusyn I
    J Toxicol Environ Health A; 2015; 78(1):15-31. PubMed ID: 25424544
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Metabolism of trichloroethylene.
    Lash LH; Fisher JW; Lipscomb JC; Parker JC
    Environ Health Perspect; 2000 May; 108 Suppl 2(Suppl 2):177-200. PubMed ID: 10807551
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Trichloroethylene-induced formic aciduria: effect of dose, sex and strain of rat.
    Yaqoob N; Evans AR; Lock EA
    Toxicology; 2013 Feb; 304():49-56. PubMed ID: 23211455
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacokinetic analysis of trichloroethylene metabolism in male B6C3F1 mice: Formation and disposition of trichloroacetic acid, dichloroacetic acid, S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine.
    Kim S; Kim D; Pollack GM; Collins LB; Rusyn I
    Toxicol Appl Pharmacol; 2009 Jul; 238(1):90-9. PubMed ID: 19409406
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bioactivation of trichloroethylene to three regioisomeric glutathione conjugates by liver fractions and recombinant human glutathione transferases: Species differences and implications for human risk assessment.
    Capinha L; Jennings P; Commandeur JNM
    Toxicol Lett; 2021 May; 341():94-106. PubMed ID: 33539969
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.