91 related articles for article (PubMed ID: 16756945)
1. Mutant Tie2 causing venous malformation signals through Shc.
Morris PN; Dunmore BJ; Brindle NP
Biochem Biophys Res Commun; 2006 Jul; 346(1):335-8. PubMed ID: 16756945
[TBL] [Abstract][Full Text] [Related]
2. Functional analysis of a mutant form of the receptor tyrosine kinase Tie2 causing venous malformations.
Morris PN; Dunmore BJ; Tadros A; Marchuk DA; Darland DC; D'Amore PA; Brindle NP
J Mol Med (Berl); 2005 Jan; 83(1):58-63. PubMed ID: 15526080
[TBL] [Abstract][Full Text] [Related]
3. Adaptor ShcA protein binds tyrosine kinase Tie2 receptor and regulates migration and sprouting but not survival of endothelial cells.
Audero E; Cascone I; Maniero F; Napione L; Arese M; Lanfrancone L; Bussolino F
J Biol Chem; 2004 Mar; 279(13):13224-33. PubMed ID: 14665640
[TBL] [Abstract][Full Text] [Related]
4. Review of the endothelial pathogenic mechanism of TIE2-related venous malformation.
Du Z; Zheng J; Zhang Z; Wang Y
J Vasc Surg Venous Lymphat Disord; 2017 Sep; 5(5):740-748. PubMed ID: 28818232
[TBL] [Abstract][Full Text] [Related]
5. Tie2-R849W mutant in venous malformations chronically activates a functional STAT1 to modulate gene expression.
Hu HT; Huang YH; Chang YA; Lee CK; Jiang MJ; Wu LW
J Invest Dermatol; 2008 Sep; 128(9):2325-33. PubMed ID: 18401423
[TBL] [Abstract][Full Text] [Related]
6. STAT1 activation by venous malformations mutant Tie2-R849W antagonizes VEGF-A-mediated angiogenic response partly via reduced bFGF production.
Huang YH; Wu MP; Pan SC; Su WC; Chen YW; Wu LW
Angiogenesis; 2013 Jan; 16(1):207-22. PubMed ID: 23086340
[TBL] [Abstract][Full Text] [Related]
7. Rapamycin improves TIE2-mutated venous malformation in murine model and human subjects.
Boscolo E; Limaye N; Huang L; Kang KT; Soblet J; Uebelhoer M; Mendola A; Natynki M; Seront E; Dupont S; Hammer J; Legrand C; Brugnara C; Eklund L; Vikkula M; Bischoff J; Boon LM
J Clin Invest; 2015 Sep; 125(9):3491-504. PubMed ID: 26258417
[TBL] [Abstract][Full Text] [Related]
8. AKT/FOXO1 axis links cross-talking of endothelial cell and pericyte in TIE2-mutated venous malformations.
Si Y; Huang J; Li X; Fu Y; Xu R; Du Y; Cheng J; Jiang H
Cell Commun Signal; 2020 Aug; 18(1):139. PubMed ID: 32867785
[TBL] [Abstract][Full Text] [Related]
9. Vascular dysmorphogenesis caused by an activating mutation in the receptor tyrosine kinase TIE2.
Vikkula M; Boon LM; Carraway KL; Calvert JT; Diamonti AJ; Goumnerov B; Pasyk KA; Marchuk DA; Warman ML; Cantley LC; Mulliken JB; Olsen BR
Cell; 1996 Dec; 87(7):1181-90. PubMed ID: 8980225
[TBL] [Abstract][Full Text] [Related]
10. ShcA and Grb2 mediate polyoma middle T antigen-induced endothelial transformation and Gab1 tyrosine phosphorylation.
Ong SH; Dilworth S; Hauck-Schmalenberger I; Pawson T; Kiefer F
EMBO J; 2001 Nov; 20(22):6327-36. PubMed ID: 11707404
[TBL] [Abstract][Full Text] [Related]
11. Transgenic Expression of A Venous Malformation Related Mutation,
Du Z; Ma HL; Zhang ZY; Zheng JW; Wang YA
Int J Med Sci; 2018; 15(4):385-394. PubMed ID: 29511374
[TBL] [Abstract][Full Text] [Related]
12. A Tie2 kinase mutation causing venous malformations increases phosphorylation rates and enhances cooperativity.
Kennedy MA; Xu Z; Wu Y; Sohl CD
Biochem Biophys Res Commun; 2019 Feb; 509(4):898-902. PubMed ID: 30638931
[TBL] [Abstract][Full Text] [Related]
13. Ponatinib Combined With Rapamycin Causes Regression of Murine Venous Malformation.
Li X; Cai Y; Goines J; Pastura P; Brichta L; Lane A; Le Cras TD; Boscolo E
Arterioscler Thromb Vasc Biol; 2019 Mar; 39(3):496-512. PubMed ID: 30626204
[TBL] [Abstract][Full Text] [Related]
14. The antiinflammatory endothelial tyrosine kinase Tie2 interacts with a novel nuclear factor-kappaB inhibitor ABIN-2.
Hughes DP; Marron MB; Brindle NP
Circ Res; 2003 Apr; 92(6):630-6. PubMed ID: 12609966
[TBL] [Abstract][Full Text] [Related]
15. Disruption of ShcA signaling halts cell proliferation--characterization of ShcC residues that influence signaling pathways using yeast.
Heinrich JN; Kwak SP; Howland DS; Chen J; Sturner S; Sullivan K; Lipinski K; Cheng KY; She Y; Lo F; Ghavami A
Cell Signal; 2006 Jun; 18(6):795-806. PubMed ID: 16126371
[TBL] [Abstract][Full Text] [Related]
16. Constitutive Active Mutant TIE2 Induces Enlarged Vascular Lumen Formation with Loss of Apico-basal Polarity and Pericyte Recruitment.
Cai Y; Schrenk S; Goines J; Davis GE; Boscolo E
Sci Rep; 2019 Aug; 9(1):12352. PubMed ID: 31451744
[TBL] [Abstract][Full Text] [Related]
17. Venous malformation-causative TIE2 mutations mediate an AKT-dependent decrease in PDGFB.
Uebelhoer M; Nätynki M; Kangas J; Mendola A; Nguyen HL; Soblet J; Godfraind C; Boon LM; Eklund L; Limaye N; Vikkula M
Hum Mol Genet; 2013 Sep; 22(17):3438-48. PubMed ID: 23633549
[TBL] [Abstract][Full Text] [Related]
18. Membrane localization of Src homology 2-containing inositol 5'-phosphatase 2 via Shc association is required for the negative regulation of insulin signaling in Rat1 fibroblasts overexpressing insulin receptors.
Ishihara H; Sasaoka T; Ishiki M; Wada T; Hori H; Kagawa S; Kobayashi M
Mol Endocrinol; 2002 Oct; 16(10):2371-81. PubMed ID: 12351701
[TBL] [Abstract][Full Text] [Related]
19. Activation of the orphan endothelial receptor Tie1 modifies Tie2-mediated intracellular signaling and cell survival.
Yuan HT; Venkatesha S; Chan B; Deutsch U; Mammoto T; Sukhatme VP; Woolf AS; Karumanchi SA
FASEB J; 2007 Oct; 21(12):3171-83. PubMed ID: 17504972
[TBL] [Abstract][Full Text] [Related]
20. Vascular endothelial growth factor activates the Tie family of receptor tyrosine kinases.
Singh H; Milner CS; Aguilar Hernandez MM; Patel N; Brindle NP
Cell Signal; 2009 Aug; 21(8):1346-50. PubMed ID: 19376222
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
