BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 16757530)

  • 1. Adult leydig cell tumors of the testis caused by germline fumarate hydratase mutations.
    Carvajal-Carmona LG; Alam NA; Pollard PJ; Jones AM; Barclay E; Wortham N; Pignatelli M; Freeman A; Pomplun S; Ellis I; Poulsom R; El-Bahrawy MA; Berney DM; Tomlinson IP
    J Clin Endocrinol Metab; 2006 Aug; 91(8):3071-5. PubMed ID: 16757530
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Comparative molecular analysis of testicular Leydig cell tumors demonstrates distinct subsets of neoplasms with aggressive histopathologic features.
    Rizzo NM; Sholl LM; Idrees MT; Cheville JC; Gupta S; Cornejo KM; Miyamoto H; Hirsch MS; Collins K; Acosta AM
    Mod Pathol; 2021 Oct; 34(10):1935-1946. PubMed ID: 34103665
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hereditary leiomyomatosis and renal cell cancer in families referred for fumarate hydratase germline mutation analysis.
    Smit DL; Mensenkamp AR; Badeloe S; Breuning MH; Simon ME; van Spaendonck KY; Aalfs CM; Post JG; Shanley S; Krapels IP; Hoefsloot LH; van Moorselaar RJ; Starink TM; Bayley JP; Frank J; van Steensel MA; Menko FH
    Clin Genet; 2011 Jan; 79(1):49-59. PubMed ID: 20618355
    [TBL] [Abstract][Full Text] [Related]  

  • 4. No germline FH mutations in familial breast cancer patients.
    Kiuru M; Lehtonen R; Eerola H; Aittomäki K; Blomqvist C; Nevanlinna H; Aaltonen LA; Launonen V
    Eur J Hum Genet; 2005 Apr; 13(4):506-9. PubMed ID: 15523491
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Germline fumarate hydratase mutations in patients with ovarian mucinous cystadenoma.
    Ylisaukko-oja SK; Cybulski C; Lehtonen R; Kiuru M; Matyjasik J; Szymañska A; Szymañska-Pasternak J; Dyrskjot L; Butzow R; Orntoft TF; Launonen V; Lubiñski J; Aaltonen LA
    Eur J Hum Genet; 2006 Jul; 14(7):880-3. PubMed ID: 16639410
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Germline mutations in FH confer predisposition to malignant pheochromocytomas and paragangliomas.
    Castro-Vega LJ; Buffet A; De Cubas AA; Cascón A; Menara M; Khalifa E; Amar L; Azriel S; Bourdeau I; Chabre O; Currás-Freixes M; Franco-Vidal V; Guillaud-Bataille M; Simian C; Morin A; Letón R; Gómez-Graña A; Pollard PJ; Rustin P; Robledo M; Favier J; Gimenez-Roqueplo AP
    Hum Mol Genet; 2014 May; 23(9):2440-6. PubMed ID: 24334767
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Fumarate Hydratase-deficient Uterine Leiomyomas Occur in Both the Syndromic and Sporadic Settings.
    Harrison WJ; Andrici J; Maclean F; Madadi-Ghahan R; Farzin M; Sioson L; Toon CW; Clarkson A; Watson N; Pickett J; Field M; Crook A; Tucker K; Goodwin A; Anderson L; Srinivasan B; Grossmann P; Martinek P; Ondič O; Hes O; Trpkov K; Clifton-Bligh RJ; Dwight T; Gill AJ
    Am J Surg Pathol; 2016 May; 40(5):599-607. PubMed ID: 26574848
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A rare cause of hypertestosteronemia in a 68-year-old patient: a Leydig cell tumor due to a somatic GNAS (guanine nucleotide-binding protein, alpha-stimulating activity polypeptide 1)-activating mutation.
    Libé R; Fratticci A; Lahlou N; Jornayvaz FR; Tissier F; Louiset E; Guibourdenche J; Vieillefond A; Zerbib M; Bertherat J
    J Androl; 2012; 33(4):578-84. PubMed ID: 22016347
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Biallelic inactivation of fumarate hydratase (FH) occurs in nonsyndromic uterine leiomyomas but is rare in other tumors.
    Lehtonen R; Kiuru M; Vanharanta S; Sjöberg J; Aaltonen LM; Aittomäki K; Arola J; Butzow R; Eng C; Husgafvel-Pursiainen K; Isola J; Järvinen H; Koivisto P; Mecklin JP; Peltomäki P; Salovaara R; Wasenius VM; Karhu A; Launonen V; Nupponen NN; Aaltonen LA
    Am J Pathol; 2004 Jan; 164(1):17-22. PubMed ID: 14695314
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Absence of activating mutations in the hot spots of the LH receptor and Gs-alpha genes in Leydig cell tumors.
    Vieira TC; Cerutti JM; Dias da Silva MR; Delcelo R; Abucham J
    J Endocrinol Invest; 2002; 25(7):598-602. PubMed ID: 12150333
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Morphology and Immunohistochemistry for 2SC and FH Aid in Detection of Fumarate Hydratase Gene Aberrations in Uterine Leiomyomas From Young Patients.
    Joseph NM; Solomon DA; Frizzell N; Rabban JT; Zaloudek C; Garg K
    Am J Surg Pathol; 2015 Nov; 39(11):1529-39. PubMed ID: 26457356
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Increased HIF1 alpha in SDH and FH deficient tumors does not cause microsatellite instability.
    Lehtonen HJ; Mäkinen MJ; Kiuru M; Laiho P; Herva R; van Minderhout I; Hogendoorn PC; Cornelisse C; Devilee P; Launonen V; Aaltonen LA
    Int J Cancer; 2007 Sep; 121(6):1386-9. PubMed ID: 17520677
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mutation screening of fumarate hydratase by multiplex ligation-dependent probe amplification: detection of exonic deletion in a patient with leiomyomatosis and renal cell cancer.
    Ahvenainen T; Lehtonen HJ; Lehtonen R; Vahteristo P; Aittomäki K; Baynam G; Dommering C; Eng C; Gruber SB; Grönberg H; Harvima R; Herva R; Hietala M; Kujala M; Kääriäinen H; Sunde L; Vierimaa O; Pollard PJ; Tomlinson IP; Björck E; Aaltonen LA; Launonen V
    Cancer Genet Cytogenet; 2008 Jun; 183(2):83-8. PubMed ID: 18503824
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Conventional renal cancer in a patient with fumarate hydratase mutation.
    Lehtonen HJ; Blanco I; Piulats JM; Herva R; Launonen V; Aaltonen LA
    Hum Pathol; 2007 May; 38(5):793-6. PubMed ID: 17270241
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Strong family history of uterine leiomyomatosis warrants fumarate hydratase mutation screening.
    Tolvanen J; Uimari O; Ryynänen M; Aaltonen LA; Vahteristo P
    Hum Reprod; 2012 Jun; 27(6):1865-9. PubMed ID: 22473397
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Fumarate hydratase deficiency and cancer: activation of hypoxia signaling?
    Ratcliffe PJ
    Cancer Cell; 2007 Apr; 11(4):303-5. PubMed ID: 17418405
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Analysis of fumarate hydratase mutations in a population-based series of early onset uterine leiomyosarcoma patients.
    Ylisaukko-oja SK; Kiuru M; Lehtonen HJ; Lehtonen R; Pukkala E; Arola J; Launonen V; Aaltonen LA
    Int J Cancer; 2006 Jul; 119(2):283-7. PubMed ID: 16477632
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Fumarate hydratase gene mutation in two young patients with sporadic uterine fibroids.
    Kubinova K; Tesarova M; Hansikova H; Vesela K; Kuzel D; Mara M
    J Obstet Gynaecol Res; 2013 Jan; 39(1):410-4. PubMed ID: 22764886
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel FH mutations in families with hereditary leiomyomatosis and renal cell cancer (HLRCC) and patients with isolated type 2 papillary renal cell carcinoma.
    Gardie B; Remenieras A; Kattygnarath D; Bombled J; Lefèvre S; Perrier-Trudova V; Rustin P; Barrois M; Slama A; Avril MF; Bessis D; Caron O; Caux F; Collignon P; Coupier I; Cremin C; Dollfus H; Dugast C; Escudier B; Faivre L; Field M; Gilbert-Dussardier B; Janin N; Leport Y; Leroux D; Lipsker D; Malthieu F; McGilliwray B; Maugard C; Méjean A; Mortemousque I; Plessis G; Poppe B; Pruvost-Balland C; Rooker S; Roume J; Soufir N; Steinraths M; Tan MH; Théodore C; Thomas L; Vabres P; Van Glabeke E; Meric JB; Verkarre V; Lenoir G; Joulin V; Deveaux S; Cusin V; Feunteun J; Teh BT; Bressac-de Paillerets B; Richard S;
    J Med Genet; 2011 Apr; 48(4):226-34. PubMed ID: 21398687
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Germline mutations in fumarate hydratase (FH) do not predispose to prostate cancer.
    Bevan S; Edwards SM; Ardern Jones A; Dowe A; Southgate C; Dearnaley D; Easton DF; Houlston RS; Eeles RA;
    Prostate Cancer Prostatic Dis; 2003; 6(1):12-4. PubMed ID: 12664059
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.