BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

117 related articles for article (PubMed ID: 16760193)

  • 1. Development of tumor targeting anti-MUC-1 multimer: effects of di-scFv unpaired cysteine location on PEGylation and tumor binding.
    Xiong CY; Natarajan A; Shi XB; Denardo GL; Denardo SJ
    Protein Eng Des Sel; 2006 Aug; 19(8):359-67. PubMed ID: 16760193
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of site-specific ScFv PEGylation for tumor-targeting pharmaceuticals.
    Natarajan A; Xiong CY; Albrecht H; DeNardo GL; DeNardo SJ
    Bioconjug Chem; 2005; 16(1):113-21. PubMed ID: 15656582
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Monospecific bivalent scFv-SH: effects of linker length and location of an engineered cysteine on production, antigen binding activity and free SH accessibility.
    Albrecht H; Denardo GL; Denardo SJ
    J Immunol Methods; 2006 Mar; 310(1-2):100-16. PubMed ID: 16499921
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Development of anti-MUC1 di-scFvs for molecular targeting of epithelial cancers, such as breast and prostate cancers.
    Albrecht H; Denardo GL; Denardo SJ
    Q J Nucl Med Mol Imaging; 2007 Dec; 51(4):304-13. PubMed ID: 17464275
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Development of multivalent radioimmunonanoparticles for cancer imaging and therapy.
    Natarajan A; Xiong CY; Gruettner C; DeNardo GL; DeNardo SJ
    Cancer Biother Radiopharm; 2008 Feb; 23(1):82-91. PubMed ID: 18298332
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Production of soluble ScFvs with C-terminal-free thiol for site-specific conjugation or stable dimeric ScFvs on demand.
    Albrecht H; Burke PA; Natarajan A; Xiong CY; Kalicinsky M; DeNardo GL; DeNardo SJ
    Bioconjug Chem; 2004; 15(1):16-26. PubMed ID: 14733579
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tailoring structure-function and pharmacokinetic properties of single-chain Fv proteins by site-specific PEGylation.
    Yang K; Basu A; Wang M; Chintala R; Hsieh MC; Liu S; Hua J; Zhang Z; Zhou J; Li M; Phyu H; Petti G; Mendez M; Janjua H; Peng P; Longley C; Borowski V; Mehlig M; Filpula D
    Protein Eng; 2003 Oct; 16(10):761-70. PubMed ID: 14600206
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Integration of PEGylation and refolding for renaturation of recombinant proteins from insoluble aggregates produced in bacteria--application to a single-chain Fv fragment.
    Kumagai I; Asano R; Nakanishi T; Hashikami K; Tanaka S; Badran A; Sanada H; Umetsu M
    J Biosci Bioeng; 2010 May; 109(5):447-52. PubMed ID: 20347766
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PEGylation and multimerization of the anti-p185HER-2 single chain Fv fragment 4D5: effects on tumor targeting.
    Kubetzko S; Balic E; Waibel R; Zangemeister-Wittke U; Plückthun A
    J Biol Chem; 2006 Nov; 281(46):35186-201. PubMed ID: 16963450
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Variable region sequence modulates periplasmic export of a single-chain Fv antibody fragment in Escherichia coli.
    Ayala M; Balint RF; Fernández-de-Cossío L; Canaán-Haden JW; Larrick JW; Gavilondo JV
    Biotechniques; 1995 May; 18(5):832, 835-8, 840-2. PubMed ID: 7619489
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Selection and characterization of anti-MUC-1 scFvs intended for targeted therapy.
    Winthrop MD; DeNardo SJ; Albrecht H; Mirick GR; Kroger LA; Lamborn KR; Venclovas C; Colvin ME; Burke PA; DeNardo GL
    Clin Cancer Res; 2003 Sep; 9(10 Pt 2):3845S-53S. PubMed ID: 14506182
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SEA-scFv as a bifunctional antibody: construction of a bacterial expression system and its functional analysis.
    Sakurai N; Kudo T; Suzuki M; Tsumoto K; Takemura S; Kodama H; Ebara S; Teramae A; Katayose Y; Shinoda M; Kurokawa T; Hinoda Y; Imai K; Matsuno S; Kumagai I
    Biochem Biophys Res Commun; 1999 Mar; 256(1):223-30. PubMed ID: 10066451
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Production of functionalized single-chain Fv antibody fragments binding to the ED-B domain of the B-isoform of fibronectin in Pichia pastoris.
    Marty C; Scheidegger P; Ballmer-Hofer K; Klemenz R; Schwendener RA
    Protein Expr Purif; 2001 Feb; 21(1):156-64. PubMed ID: 11162401
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Human single-chain Fv antibodies to MUC1 core peptide selected from phage display libraries recognize unique epitopes and predominantly bind adenocarcinoma.
    Henderikx P; Kandilogiannaki M; Petrarca C; von Mensdorff-Pouilly S; Hilgers JH; Krambovitis E; Arends JW; Hoogenboom HR
    Cancer Res; 1998 Oct; 58(19):4324-32. PubMed ID: 9766660
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Direct detection and quantitation of a distinct T-cell epitope derived from tumor-specific epithelial cell-associated mucin using human recombinant antibodies endowed with the antigen-specific, major histocompatibility complex-restricted specificity of T cells.
    Cohen CJ; Hoffmann N; Farago M; Hoogenboom HR; Eisenbach L; Reiter Y
    Cancer Res; 2002 Oct; 62(20):5835-44. PubMed ID: 12384546
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Site-directed pegylation of recombinant interleukin-2 at its glycosylation site.
    Goodson RJ; Katre NV
    Biotechnology (N Y); 1990 Apr; 8(4):343-6. PubMed ID: 1366535
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Enhancement of scFv fragment reactivity with target antigens in binding assays following mixing with anti-tag monoclonal antibodies.
    Wang X; Campoli M; Ko E; Luo W; Ferrone S
    J Immunol Methods; 2004 Nov; 294(1-2):23-35. PubMed ID: 15604013
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Site-specific PEGylation of bone morphogenetic protein-2 cysteine analogues.
    Hu J; Duppatla V; Harth S; Schmitz W; Sebald W
    Bioconjug Chem; 2010 Oct; 21(10):1762-72. PubMed ID: 20886828
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Enhancement of the therapeutic index: from nonmyeloablative and myeloablative toward pretargeted radioimmunotherapy for metastatic prostate cancer.
    DeNardo SJ; Richman CM; Albrecht H; Burke PA; Natarajan A; Yuan A; Gregg JP; O'Donnell RT; DeNardo GL
    Clin Cancer Res; 2005 Oct; 11(19 Pt 2):7187s-7194s. PubMed ID: 16203820
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure/activity studies of the anti-MUC1 monoclonal antibody C595 and synthetic MUC1 mucin-core-related peptides and glycopeptides.
    Spencer DI; Missailidis S; Denton G; Murray A; Brady K; Matteis CI; Searle MS; Tendler SJ; Price MR
    Biospectroscopy; 1999; 5(2):79-91. PubMed ID: 10217327
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.