397 related articles for article (PubMed ID: 16763016)
1. Which hydroxy? Evidence for species differences in the regioselectivity of glucuronidation in rat, dog, and human in vitro systems and dog in vivo.
Martin IJ; Lewis RJ; Bernstein MA; Beattie IG; Martin CA; Riley RJ; Springthorpe B
Drug Metab Dispos; 2006 Sep; 34(9):1502-7. PubMed ID: 16763016
[TBL] [Abstract][Full Text] [Related]
2. Metabolism of MK-0524, a prostaglandin D2 receptor 1 antagonist, in microsomes and hepatocytes from preclinical species and humans.
Dean BJ; Chang S; Silva Elipe MV; Xia YQ; Braun M; Soli E; Zhao Y; Franklin RB; Karanam B
Drug Metab Dispos; 2007 Feb; 35(2):283-92. PubMed ID: 17132765
[TBL] [Abstract][Full Text] [Related]
3. Structural characterization of anti-HIV drug candidate PA-457 [3-O-(3',3'-dimethylsuccinyl)-betulinic acid] and its acyl glucuronides in rat bile and evaluation of in vitro stability in human and animal liver microsomes and plasma.
Wen Z; Stern ST; Martin DE; Lee KH; Smith PC
Drug Metab Dispos; 2006 Sep; 34(9):1436-42. PubMed ID: 16751262
[TBL] [Abstract][Full Text] [Related]
4. Formation and protein binding of the acyl glucuronide of a leukotriene B4 antagonist (SB-209247): relation to species differences in hepatotoxicity.
Kenny JR; Maggs JL; Tettey JN; Harrell AW; Parker SG; Clarke SE; Park BK
Drug Metab Dispos; 2005 Feb; 33(2):271-81. PubMed ID: 15523047
[TBL] [Abstract][Full Text] [Related]
5. Synthesis, structure characterization, and enzyme screening of clenbuterol glucuronides.
Alonen A; Gartman M; Aitio O; Finel M; Yli-Kauhaluoma J; Kostiainen R
Eur J Pharm Sci; 2009 Jul; 37(5):581-7. PubMed ID: 19447177
[TBL] [Abstract][Full Text] [Related]
6. Identification and characterization of two chloramphenicol glucuronides from the in vitro glucuronidation of chloramphenicol in human liver microsomes.
Chen M; Howe D; Leduc B; Kerr S; Williams DA
Xenobiotica; 2007 Sep; 37(9):954-71. PubMed ID: 17896323
[TBL] [Abstract][Full Text] [Related]
7. Species differences in the elimination of a peroxisome proliferator-activated receptor agonist highlighted by oxidative metabolism of its acyl glucuronide.
Kochansky CJ; Xia YQ; Wang S; Cato B; Creighton M; Vincent SH; Franklin RB; Reed JR
Drug Metab Dispos; 2005 Dec; 33(12):1894-904. PubMed ID: 16183782
[TBL] [Abstract][Full Text] [Related]
8. Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of ezetimibe (Zetia).
Ghosal A; Hapangama N; Yuan Y; Achanfuo-Yeboah J; Iannucci R; Chowdhury S; Alton K; Patrick JE; Zbaida S
Drug Metab Dispos; 2004 Mar; 32(3):314-20. PubMed ID: 14977865
[TBL] [Abstract][Full Text] [Related]
9. Enzyme-assisted synthesis and characterization of glucuronide conjugates of neuroactive steroids.
Jäntti SE; Kiriazis A; Reinilä RR; Kostiainen RK; Ketola RA
Steroids; 2007 Mar; 72(3):287-96. PubMed ID: 17250861
[TBL] [Abstract][Full Text] [Related]
10. Biotransformation of the anti-angiogenic compound SU5416.
Antonian L; Zhang H; Yang C; Wagner G; Shawver LK; Shet M; Ogilvie B; Madan A; Parkinson A
Drug Metab Dispos; 2000 Dec; 28(12):1505-12. PubMed ID: 11095590
[TBL] [Abstract][Full Text] [Related]
11. Metabolism of prazosin in rat, dog, and human liver microsomes and cryopreserved rat and human hepatocytes and characterization of metabolites by liquid chromatography/tandem mass spectrometry.
Erve JC; Vashishtha SC; DeMaio W; Talaat RE
Drug Metab Dispos; 2007 Jun; 35(6):908-16. PubMed ID: 17353349
[TBL] [Abstract][Full Text] [Related]
12. Identification of a novel N-carbamoyl glucuronide: in vitro, in vivo, and mechanistic studies.
Gunduz M; Argikar UA; Baeschlin D; Ferreira S; Hosagrahara V; Harriman S
Drug Metab Dispos; 2010 Mar; 38(3):361-7. PubMed ID: 20008038
[TBL] [Abstract][Full Text] [Related]
13. Disposition of the dipeptidyl peptidase 4 inhibitor sitagliptin in rats and dogs.
Beconi MG; Reed JR; Teffera Y; Xia YQ; Kochansky CJ; Liu DQ; Xu S; Elmore CS; Ciccotto S; Hora DF; Stearns RA; Vincent SH
Drug Metab Dispos; 2007 Apr; 35(4):525-32. PubMed ID: 17220241
[TBL] [Abstract][Full Text] [Related]
14. Preclinical pharmacokinetics and metabolism of 6-(4-(2,5-difluorophenyl)oxazol-5-yl)-3-isopropyl-[1,2,4]-triazolo[4,3-a]pyridine, a novel and selective p38alpha inhibitor: identification of an active metabolite in preclinical species and human liver microsomes.
Kalgutkar AS; Hatch HL; Kosea F; Nguyen HT; Choo EF; McClure KF; Taylor TJ; Henne KR; Kuperman AV; Dombroski MA; Letavic MA
Biopharm Drug Dispos; 2006 Nov; 27(8):371-86. PubMed ID: 16944451
[TBL] [Abstract][Full Text] [Related]
15. HPLC-NMR with severe column overloading: fast-track metabolite identification in urine and bile samples from rat and dog treated with [14C]-ZD6126.
Lenz EM; D'Souza RA; Jordan AC; King CD; Smith SM; Phillips PJ; McCormick AD; Roberts DW
J Pharm Biomed Anal; 2007 Feb; 43(3):1065-77. PubMed ID: 17030109
[TBL] [Abstract][Full Text] [Related]
16. Species difference in glucuronidation formation kinetics with a selective mTOR inhibitor.
Berry LM; Liu J; Colletti A; Krolikowski P; Zhao Z; Teffera Y
Drug Metab Dispos; 2014 Apr; 42(4):707-17. PubMed ID: 24423753
[TBL] [Abstract][Full Text] [Related]
17. Species differences in the biotransformation of an alpha 4 beta 2 nicotinic acetylcholine receptor partial agonist: the effects of distinct glucuronide metabolites on overall compound disposition.
Shaffer CL; Gunduz M; Ryder TF; O'Connell TN
Drug Metab Dispos; 2010 Feb; 38(2):292-301. PubMed ID: 19910512
[TBL] [Abstract][Full Text] [Related]
18. Comparative metabolism of 14C-labeled apixaban in mice, rats, rabbits, dogs, and humans.
Zhang D; He K; Raghavan N; Wang L; Mitroka J; Maxwell BD; Knabb RM; Frost C; Schuster A; Hao F; Gu Z; Humphreys WG; Grossman SJ
Drug Metab Dispos; 2009 Aug; 37(8):1738-48. PubMed ID: 19420130
[TBL] [Abstract][Full Text] [Related]
19. In vitro and in vivo metabolism of desogestrel in several species.
Verhoeven CH; Krebbers SF; Wagenaars GN; Vos RM
Drug Metab Dispos; 1998 Sep; 26(9):927-36. PubMed ID: 9733673
[TBL] [Abstract][Full Text] [Related]
20. Bexarotene metabolism in rat, dog, and human, synthesis of oxidative metabolites, and in vitro activity at retinoid receptors.
Howell SR; Shirley MA; Grese TA; Neel DA; Wells KE; Ulm EH
Drug Metab Dispos; 2001 Jul; 29(7):990-8. PubMed ID: 11408365
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
