BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

255 related articles for article (PubMed ID: 16766048)

  • 1. The nicotinic acid receptor GPR109A (HM74A or PUMA-G) as a new therapeutic target.
    Offermanns S
    Trends Pharmacol Sci; 2006 Jul; 27(7):384-90. PubMed ID: 16766048
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Nicotinic acid (niacin): new lipid-independent mechanisms of action and therapeutic potentials.
    Lukasova M; Hanson J; Tunaru S; Offermanns S
    Trends Pharmacol Sci; 2011 Dec; 32(12):700-7. PubMed ID: 21944259
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Nicotinic acid: pharmacological effects and mechanisms of action.
    Gille A; Bodor ET; Ahmed K; Offermanns S
    Annu Rev Pharmacol Toxicol; 2008; 48():79-106. PubMed ID: 17705685
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Future of GPR109A agonists in the treatment of dyslipidaemia.
    Wanders D; Judd RL
    Diabetes Obes Metab; 2011 Aug; 13(8):685-91. PubMed ID: 21418500
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of determinants of ligand binding to the nicotinic acid receptor GPR109A (HM74A/PUMA-G).
    Tunaru S; Lättig J; Kero J; Krause G; Offermanns S
    Mol Pharmacol; 2005 Nov; 68(5):1271-80. PubMed ID: 16099840
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Flushing out the role of GPR109A (HM74A) in the clinical efficacy of nicotinic acid.
    Pike NB
    J Clin Invest; 2005 Dec; 115(12):3400-3. PubMed ID: 16322787
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Nicotinic acid (niacin) receptor agonists: will they be useful therapeutic agents?
    Kamanna VS; Kashyap ML
    Am J Cardiol; 2007 Dec; 100(11 A):S53-61. PubMed ID: 18047854
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The psoriasis drug monomethylfumarate is a potent nicotinic acid receptor agonist.
    Tang H; Lu JY; Zheng X; Yang Y; Reagan JD
    Biochem Biophys Res Commun; 2008 Oct; 375(4):562-5. PubMed ID: 18722346
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of a nicotinic acid receptor: is this the molecular target for the oldest lipid-lowering drug?
    Pike NB; Wise A
    Curr Opin Investig Drugs; 2004 Mar; 5(3):271-5. PubMed ID: 15083592
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Triglyceride modulation by acifran analogs: activity towards the niacin high and low affinity G protein-coupled receptors HM74A and HM74.
    Mahboubi K; Witman-Jones T; Adamus JE; Letsinger JT; Whitehouse D; Moorman AR; Sawicki D; Bergenhem N; Ross SA
    Biochem Biophys Res Commun; 2006 Feb; 340(2):482-90. PubMed ID: 16389067
    [TBL] [Abstract][Full Text] [Related]  

  • 11. GPR109A (PUMA-G/HM74A) mediates nicotinic acid-induced flushing.
    Benyó Z; Gille A; Kero J; Csiky M; Suchánková MC; Nüsing RM; Moers A; Pfeffer K; Offermanns S
    J Clin Invest; 2005 Dec; 115(12):3634-40. PubMed ID: 16322797
    [TBL] [Abstract][Full Text] [Related]  

  • 12. New evidence for nicotinic acid treatment to reduce atherosclerosis.
    Montecucco F; Quercioli A; Dallegri F; Viviani GL; Mach F
    Expert Rev Cardiovasc Ther; 2010 Oct; 8(10):1457-67. PubMed ID: 20936932
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Recent progress in the discovery of niacin receptor agonists.
    Semple G; Boatman PD; Richman JG
    Curr Opin Drug Discov Devel; 2007 Jul; 10(4):452-9. PubMed ID: 17659487
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect.
    Tunaru S; Kero J; Schaub A; Wufka C; Blaukat A; Pfeffer K; Offermanns S
    Nat Med; 2003 Mar; 9(3):352-5. PubMed ID: 12563315
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Role of HCA₂ (GPR109A) in nicotinic acid and fumaric acid ester-induced effects on the skin.
    Hanson J; Gille A; Offermanns S
    Pharmacol Ther; 2012 Oct; 136(1):1-7. PubMed ID: 22743741
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Nicotinic acid: an old drug with a promising future.
    Bodor ET; Offermanns S
    Br J Pharmacol; 2008 Mar; 153 Suppl 1(Suppl 1):S68-75. PubMed ID: 18037924
    [TBL] [Abstract][Full Text] [Related]  

  • 17. HM74a agonists: will they be the new generation of nicotinic acid?
    Martres P
    Curr Top Med Chem; 2009; 9(5):428-35. PubMed ID: 19519459
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery of novel tricyclic full agonists for the G-protein-coupled niacin receptor 109A with minimized flushing in rats.
    Shen HC; Ding FX; Deng Q; Wilsie LC; Krsmanovic ML; Taggart AK; Carballo-Jane E; Ren N; Cai TQ; Wu TJ; Wu KK; Cheng K; Chen Q; Wolff MS; Tong X; Holt TG; Waters MG; Hammond ML; Tata JR; Colletti SL
    J Med Chem; 2009 Apr; 52(8):2587-602. PubMed ID: 19309152
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nicotinic acid receptor subtypes and their ligands.
    Soudijn W; van Wijngaarden I; Ijzerman AP
    Med Res Rev; 2007 May; 27(3):417-33. PubMed ID: 17238156
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Novel patent publications on high-affinity nicotinic acid receptor agonists.
    Shen HC; Colletti SL
    Expert Opin Ther Pat; 2009 Jul; 19(7):957-67. PubMed ID: 19552512
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.