BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

141 related articles for article (PubMed ID: 16767162)

  • 1. Modulation of alpha-catenin Tyr phosphorylation by SHP2 positively effects cell transformation induced by the constitutively active FGFR3.
    Burks J; Agazie YM
    Oncogene; 2006 Nov; 25(54):7166-79. PubMed ID: 16767162
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The phosphotyrosine phosphatase SHP2 is a critical mediator of transformation induced by the oncogenic fibroblast growth factor receptor 3.
    Agazie YM; Movilla N; Ischenko I; Hayman MJ
    Oncogene; 2003 Oct; 22(44):6909-18. PubMed ID: 14534538
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of Sertoli-germ cell adherens junction dynamics via changes in protein-protein interactions of the N-cadherin-beta-catenin protein complex which are possibly mediated by c-Src and myotubularin-related protein 2: an in vivo study using an androgen suppression model.
    Zhang J; Wong CH; Xia W; Mruk DD; Lee NP; Lee WM; Cheng CY
    Endocrinology; 2005 Mar; 146(3):1268-84. PubMed ID: 15591133
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Deoxycholic acid differentially regulates focal adhesion kinase phosphorylation: role of tyrosine phosphatase ShP2.
    Khare S; Holgren C; Samarel AM
    Am J Physiol Gastrointest Liver Physiol; 2006 Dec; 291(6):G1100-12. PubMed ID: 16920701
    [TBL] [Abstract][Full Text] [Related]  

  • 5. TNF-alpha induces tyrosine phosphorylation and recruitment of the Src homology protein-tyrosine phosphatase 2 to the gp130 signal-transducing subunit of the IL-6 receptor complex.
    Bode JG; Schweigart J; Kehrmann J; Ehlting C; Schaper F; Heinrich PC; Häussinger D
    J Immunol; 2003 Jul; 171(1):257-66. PubMed ID: 12817006
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Interleukin-3 induces association of the protein-tyrosine phosphatase SHP2 and phosphatidylinositol 3-kinase with a 100-kDa tyrosine-phosphorylated protein in hemopoietic cells.
    Craddock BL; Welham MJ
    J Biol Chem; 1997 Nov; 272(46):29281-9. PubMed ID: 9361008
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tyrosyl phosphorylation of Shp2 is required for normal ERK activation in response to some, but not all, growth factors.
    Araki T; Nawa H; Neel BG
    J Biol Chem; 2003 Oct; 278(43):41677-84. PubMed ID: 12923167
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Activation of the protein tyrosine phosphatase SHP2 via the interleukin-6 signal transducing receptor protein gp130 requires tyrosine kinase Jak1 and limits acute-phase protein expression.
    Schaper F; Gendo C; Eck M; Schmitz J; Grimm C; Anhuf D; Kerr IM; Heinrich PC
    Biochem J; 1998 Nov; 335 ( Pt 3)(Pt 3):557-65. PubMed ID: 9794795
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The cytoplasmic tyrosine kinase Pyk2 as a novel effector of fibroblast growth factor receptor 3 activation.
    Meyer AN; Gastwirt RF; Schlaepfer DD; Donoghue DJ
    J Biol Chem; 2004 Jul; 279(27):28450-7. PubMed ID: 15105428
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutation of Thr466 in SHP2 abolishes its phosphatase activity, but provides a new substrate-trapping mutant.
    Merritt R; Hayman MJ; Agazie YM
    Biochim Biophys Acta; 2006 Jan; 1763(1):45-56. PubMed ID: 16413071
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Shp2, an SH2-containing protein-tyrosine phosphatase, positively regulates receptor tyrosine kinase signaling by dephosphorylating and inactivating the inhibitor Sprouty.
    Hanafusa H; Torii S; Yasunaga T; Matsumoto K; Nishida E
    J Biol Chem; 2004 May; 279(22):22992-5. PubMed ID: 15031289
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SHP2 association with VE-cadherin complexes in human endothelial cells is regulated by thrombin.
    Ukropec JA; Hollinger MK; Salva SM; Woolkalis MJ
    J Biol Chem; 2000 Feb; 275(8):5983-6. PubMed ID: 10681592
    [TBL] [Abstract][Full Text] [Related]  

  • 13. SHP2 Potentiates the Oncogenic Activity of β-Catenin to Promote Triple-Negative Breast Cancer.
    Martin E; Agazie YM
    Mol Cancer Res; 2021 Nov; 19(11):1946-1956. PubMed ID: 34389690
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of the platelet-derived growth factor receptor-beta by G protein-coupled receptor kinase-5 in vascular smooth muscle cells involves the phosphatase Shp2.
    Wu JH; Goswami R; Cai X; Exum ST; Huang X; Zhang L; Brian L; Premont RT; Peppel K; Freedman NJ
    J Biol Chem; 2006 Dec; 281(49):37758-72. PubMed ID: 17018529
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The protein tyrosine phosphatase, Shp2, is required for the complete activation of the RAS/MAPK pathway by brain-derived neurotrophic factor.
    Easton JB; Royer AR; Middlemas DS
    J Neurochem; 2006 May; 97(3):834-45. PubMed ID: 16573649
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Beta4 integrin activates a Shp2-Src signaling pathway that sustains HGF-induced anchorage-independent growth.
    Bertotti A; Comoglio PM; Trusolino L
    J Cell Biol; 2006 Dec; 175(6):993-1003. PubMed ID: 17158954
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Receptor-specific regulation of phosphatidylinositol 3'-kinase activation by the protein tyrosine phosphatase Shp2.
    Zhang SQ; Tsiaras WG; Araki T; Wen G; Minichiello L; Klein R; Neel BG
    Mol Cell Biol; 2002 Jun; 22(12):4062-72. PubMed ID: 12024020
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase.
    Besset V; Scott RP; Ibáñez CF
    J Biol Chem; 2000 Dec; 275(50):39159-66. PubMed ID: 10995764
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular mechanism for a role of SHP2 in epidermal growth factor receptor signaling.
    Agazie YM; Hayman MJ
    Mol Cell Biol; 2003 Nov; 23(21):7875-86. PubMed ID: 14560030
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The tyrosine phosphatase Shp2 interacts with NPM-ALK and regulates anaplastic lymphoma cell growth and migration.
    Voena C; Conte C; Ambrogio C; Boeri Erba E; Boccalatte F; Mohammed S; Jensen ON; Palestro G; Inghirami G; Chiarle R
    Cancer Res; 2007 May; 67(9):4278-86. PubMed ID: 17483340
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.