BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

114 related articles for article (PubMed ID: 1677245)

  • 1. Imidazopyridines: towards novel hypnotic and anxiolytic drugs.
    George P; Rossey G; Depoortere H; Mompon B; Allen J; Wick A
    Farmaco; 1991 Jan; 46(1 Suppl):277-88. PubMed ID: 1677245
    [No Abstract]   [Full Text] [Related]  

  • 2. Tolerance to a new class of non-benzodiazepine anxiolytics.
    Chodera A; Nowakowska E; Bartczak G
    Pol J Pharmacol; 1994; 46(5):479-81. PubMed ID: 7894538
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 5-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]-2,3'-bipyridine: a highly potent, orally active metabotropic glutamate subtype 5 (mGlu5) receptor antagonist with anxiolytic activity.
    Roppe JR; Wang B; Huang D; Tehrani L; Kamenecka T; Schweiger EJ; Anderson JJ; Brodkin J; Jiang X; Cramer M; Chung J; Reyes-Manalo G; Munoz B; Cosford ND
    Bioorg Med Chem Lett; 2004 Aug; 14(15):3993-6. PubMed ID: 15225713
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of imidazo[1,2-b][1,2,4]triazines as GABA(A) alpha2/3 subtype selective agonists for the treatment of anxiety.
    Russell MG; Carling RW; Street LJ; Hallett DJ; Goodacre S; Mezzogori E; Reader M; Cook SM; Bromidge FA; Newman R; Smith AJ; Wafford KA; Marshall GR; Reynolds DS; Dias R; Ferris P; Stanley J; Lincoln R; Tye SJ; Sheppard WF; Sohal B; Pike A; Dominguez M; Atack JR; Castro JL
    J Med Chem; 2006 Feb; 49(4):1235-8. PubMed ID: 16480260
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and SAR of 2-(4-fluorophenyl)-3-pyrimidin-4-ylimidazo[1,2-a]pyridine derivatives as anticoccidial agents.
    Feng D; Fisher M; Liang GB; Qian X; Brown C; Gurnett A; Leavitt PS; Liberator PA; Mathew J; Misura A; Samaras S; Tamas T; Schmatz DM; Wyvratt M; Biftu T
    Bioorg Med Chem Lett; 2006 Dec; 16(23):5978-81. PubMed ID: 17000105
    [TBL] [Abstract][Full Text] [Related]  

  • 6. [Imidazopyridines, an alternative to benzodiazepines].
    Dessibourg CA
    Schweiz Rundsch Med Prax; 1992 Apr; 81(17):555-6. PubMed ID: 1349764
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 7-(1,1-Dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine: a functionally selective gamma-aminobutyric acid(A) (GABA(A)) alpha2/alpha3-subtype selective agonist that exhibits potent anxiolytic activity but is not sedating in animal models.
    Carling RW; Madin A; Guiblin A; Russell MG; Moore KW; Mitchinson A; Sohal B; Pike A; Cook SM; Ragan IC; McKernan RM; Quirk K; Ferris P; Marshall G; Thompson SA; Wafford KA; Dawson GR; Atack JR; Harrison T; Castro JL; Street LJ
    J Med Chem; 2005 Nov; 48(23):7089-92. PubMed ID: 16279764
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis of imidazo[1,2-a]pyridines as antiviral agents.
    Gueiffier A; Mavel S; Lhassani M; Elhakmaoui A; Snoeck R; Andrei G; Chavignon O; Teulade JC; Witvrouw M; Balzarini J; De Clercq E; Chapat JP
    J Med Chem; 1998 Dec; 41(25):5108-12. PubMed ID: 9836626
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis, structure-activity relationships, and anxiolytic activity of 7-aryl-6,7-dihydroimidazoimidazole corticotropin-releasing factor 1 receptor antagonists.
    Han X; Michne JA; Pin SS; Burris KD; Balanda LA; Fung LK; Fiedler T; Browman KE; Taber MT; Zhang J; Dubowchik GM
    Bioorg Med Chem Lett; 2005 Sep; 15(17):3870-3. PubMed ID: 15990298
    [TBL] [Abstract][Full Text] [Related]  

  • 10. General and efficient copper-catalyzed three-component coupling reaction towards imidazoheterocycles: one-pot synthesis of alpidem and zolpidem.
    Chernyak N; Gevorgyan V
    Angew Chem Int Ed Engl; 2010 Apr; 49(15):2743-6. PubMed ID: 20213787
    [No Abstract]   [Full Text] [Related]  

  • 11. A novel selective GABA(A) alpha1 receptor agonist displaying sedative and anxiolytic-like properties in rodents.
    Selleri S; Bruni F; Costagli C; Costanzo A; Guerrini G; Ciciani G; Gratteri P; Besnard F; Costa B; Montali M; Martini C; Fohlin J; De Siena G; Aiello PM
    J Med Chem; 2005 Oct; 48(21):6756-60. PubMed ID: 16220991
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis and biological activity of acyl substituted 3-amino-5-methyl-1,4,5,7-tetrahydropyrazolo[3,4-b]pyridin-6-ones as potential hypnotic drugs.
    Falcó JL; Lloveras M; Buira I; Teixidó J; Borrell JI; Méndez E; Terencio J; Palomer A; Guglietta A
    Eur J Med Chem; 2005 Nov; 40(11):1179-87. PubMed ID: 16095764
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of allosteric potentiators for the metabotropic glutamate 2 receptor: synthesis and subtype selectivity of N-(4-(2-methoxyphenoxy)phenyl)-N-(2,2,2- trifluoroethylsulfonyl)pyrid-3-ylmethylamine.
    Johnson MP; Baez M; Jagdmann GE; Britton TC; Large TH; Callagaro DO; Tizzano JP; Monn JA; Schoepp DD
    J Med Chem; 2003 Jul; 46(15):3189-92. PubMed ID: 12852748
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Studies on hypnotic and anticonvulsant agents related to the thiazole part of thiamine.
    Lindberg UH
    Acta Pharm Suec; 1971 Dec; 8(6):647-60. PubMed ID: 5139739
    [No Abstract]   [Full Text] [Related]  

  • 15. Functionalized 3-amino-imidazo[1,2-a]pyridines: a novel class of drug-like Mycobacterium tuberculosis glutamine synthetase inhibitors.
    Odell LR; Nilsson MT; Gising J; Lagerlund O; Muthas D; Nordqvist A; Karlén A; Larhed M
    Bioorg Med Chem Lett; 2009 Aug; 19(16):4790-3. PubMed ID: 19560924
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and hypnotic activity of some 2-thioxo-4,5-imidazolidinedione derivatives.
    Ozkirimli S; Hamali O
    Farmaco; 1995 Jan; 50(1):65-7. PubMed ID: 7702724
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis, evaluation of biological activity and SAR of new thioalkyl derivatives of pyridine.
    Sh Dashyan S; Babaev EV; Ayvazyan AG; Mamyan SS; Paronikyan EG; Nikoghosyan TA; Hunanyan LS; Paronikyan RG
    Bioorg Chem; 2024 Jul; 148():107435. PubMed ID: 38762999
    [TBL] [Abstract][Full Text] [Related]  

  • 18. IRAK-4 inhibitors. Part II: a structure-based assessment of imidazo[1,2-a]pyridine binding.
    Buckley GM; Ceska TA; Fraser JL; Gowers L; Groom CR; Higueruelo AP; Jenkins K; Mack SR; Morgan T; Parry DM; Pitt WR; Rausch O; Richard MD; Sabin V
    Bioorg Med Chem Lett; 2008 Jun; 18(11):3291-5. PubMed ID: 18482836
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Zolpidem and alpidem: two imidazopyridines with selectivity for omega 1- and omega 3-receptor subtypes.
    Langer SZ; Arbilla S; Benavides J; Scatton B
    Adv Biochem Psychopharmacol; 1990; 46():61-72. PubMed ID: 1981304
    [No Abstract]   [Full Text] [Related]  

  • 20. Design, synthesis, and pharmacological evaluation of new neuroactive pyrazolo[3,4-b]pyrrolo[3,4-d]pyridine derivatives with in vivo hypnotic and analgesic profile.
    Menegatti R; Silva GM; Zapata-Sudo G; Raimundo JM; Sudo RT; Barreiro EJ; Fraga CA
    Bioorg Med Chem; 2006 Feb; 14(3):632-40. PubMed ID: 16198114
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.