BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 16776571)

  • 1. Alpha1-antitrypsin gene therapy modulates cellular immunity and efficiently prevents type 1 diabetes in nonobese diabetic mice.
    Lu Y; Tang M; Wasserfall C; Kou Z; Campbell-Thompson M; Gardemann T; Crawford J; Atkinson M; Song S
    Hum Gene Ther; 2006 Jun; 17(6):625-34. PubMed ID: 16776571
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Recombinant adeno-associated virus-mediated alpha-1 antitrypsin gene therapy prevents type I diabetes in NOD mice.
    Song S; Goudy K; Campbell-Thompson M; Wasserfall C; Scott-Jorgensen M; Wang J; Tang Q; Crawford JM; Ellis TM; Atkinson MA; Flotte TR
    Gene Ther; 2004 Jan; 11(2):181-6. PubMed ID: 14712302
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Distinct immune responses to transgene products from rAAV1 and rAAV8 vectors.
    Lu Y; Song S
    Proc Natl Acad Sci U S A; 2009 Oct; 106(40):17158-62. PubMed ID: 19805176
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Systemic overexpression of IL-10 induces CD4+CD25+ cell populations in vivo and ameliorates type 1 diabetes in nonobese diabetic mice in a dose-dependent fashion.
    Goudy KS; Burkhardt BR; Wasserfall C; Song S; Campbell-Thompson ML; Brusko T; Powers MA; Clare-Salzler MJ; Sobel ES; Ellis TM; Flotte TR; Atkinson MA
    J Immunol; 2003 Sep; 171(5):2270-8. PubMed ID: 12928371
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Suppression of autoimmune diabetes by viral IL-10 gene transfer.
    Yang Z; Chen M; Wu R; Fialkow LB; Bromberg JS; McDuffie M; Naji A; Nadler JL
    J Immunol; 2002 Jun; 168(12):6479-85. PubMed ID: 12055268
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phase I trial of intramuscular injection of a recombinant adeno-associated virus alpha 1-antitrypsin (rAAV2-CB-hAAT) gene vector to AAT-deficient adults.
    Flotte TR; Brantly ML; Spencer LT; Byrne BJ; Spencer CT; Baker DJ; Humphries M
    Hum Gene Ther; 2004 Jan; 15(1):93-128. PubMed ID: 14965381
    [TBL] [Abstract][Full Text] [Related]  

  • 7. In Vivo Analysis of Alpha-1-Antitrypsin Functions in Autoimmune Disease Models.
    Song S; Lu Y; Elshikha AS
    Methods Mol Biol; 2018; 1826():143-155. PubMed ID: 30194599
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Therapeutic level of functional human alpha 1 antitrypsin (hAAT) secreted from murine muscle transduced by adeno-associated virus (rAAV1) vector.
    Lu Y; Choi YK; Campbell-Thompson M; Li C; Tang Q; Crawford JM; Flotte TR; Song S
    J Gene Med; 2006 Jun; 8(6):730-5. PubMed ID: 16518879
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Gene delivery GAD 500 autoantigen by AAV serotype 1 prevented diabetes in NOD mice: transduction efficiency do not play important roles.
    Han G; Wang R; Chen G; Wang J; Xu R; Feng J; Yu M; Wu X; Qian J; Shen B; Li Y
    Immunol Lett; 2008 Jan; 115(2):110-6. PubMed ID: 18045698
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Adeno-associated virus vector-mediated IL-10 gene delivery prevents type 1 diabetes in NOD mice.
    Goudy K; Song S; Wasserfall C; Zhang YC; Kapturczak M; Muir A; Powers M; Scott-Jorgensen M; Campbell-Thompson M; Crawford JM; Ellis TM; Flotte TR; Atkinson MA
    Proc Natl Acad Sci U S A; 2001 Nov; 98(24):13913-8. PubMed ID: 11717448
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Alpha-1-antitrypsin for the improvement of autoimmunity and allograft rejection in beta cell transplantation.
    Ye J; Liao YT; Jian YQ; Zhang XD; Wei P; Qi H; Deng CY; Li FR
    Immunol Lett; 2013 Feb; 150(1-2):61-8. PubMed ID: 23333354
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Efficient hepatic delivery and expression from a recombinant adeno-associated virus 8 pseudotyped alpha1-antitrypsin vector.
    Conlon TJ; Cossette T; Erger K; Choi YK; Clarke T; Scott-Jorgensen M; Song S; Campbell-Thompson M; Crawford J; Flotte TR
    Mol Ther; 2005 Nov; 12(5):867-75. PubMed ID: 16085464
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Intradermal alpha1-antitrypsin therapy avoids fatal anaphylaxis, prevents type 1 diabetes and reverses hyperglycaemia in the NOD mouse model of the disease.
    Ma H; Lu Y; Li H; Campbell-Thompson M; Parker M; Wasserfall C; Haller M; Brantly M; Schatz D; Atkinson M; Song S
    Diabetologia; 2010 Oct; 53(10):2198-204. PubMed ID: 20593162
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sustained transgene expression despite T lymphocyte responses in a clinical trial of rAAV1-AAT gene therapy.
    Brantly ML; Chulay JD; Wang L; Mueller C; Humphries M; Spencer LT; Rouhani F; Conlon TJ; Calcedo R; Betts MR; Spencer C; Byrne BJ; Wilson JM; Flotte TR
    Proc Natl Acad Sci U S A; 2009 Sep; 106(38):16363-8. PubMed ID: 19706466
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Expression of IL-2 in β cells by AAV8 gene transfer in pre-diabetic NOD mice prevents diabetes through activation of FoxP3-positive regulatory T cells.
    Flores RR; Zhou L; Robbins PD
    Gene Ther; 2014 Aug; 21(8):715-22. PubMed ID: 24849041
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phase 2 clinical trial of a recombinant adeno-associated viral vector expressing α1-antitrypsin: interim results.
    Flotte TR; Trapnell BC; Humphries M; Carey B; Calcedo R; Rouhani F; Campbell-Thompson M; Yachnis AT; Sandhaus RA; McElvaney NG; Mueller C; Messina LM; Wilson JM; Brantly M; Knop DR; Ye GJ; Chulay JD
    Hum Gene Ther; 2011 Oct; 22(10):1239-47. PubMed ID: 21609134
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inducible adeno-associated virus-mediated IL-2 gene therapy prevents autoimmune diabetes.
    Goudy KS; Johnson MC; Garland A; Li C; Samulski RJ; Wang B; Tisch R
    J Immunol; 2011 Mar; 186(6):3779-86. PubMed ID: 21317396
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Retroviral delivery of GAD-IgG fusion construct induces tolerance and modulates diabetes: a role for CD4+ regulatory T cells and TGF-beta?
    Song L; Wang J; Wang R; Yu M; Sun Y; Han G; Li Y; Qian J; Scott DW; Kang Y; Soukhareva N; Shen B
    Gene Ther; 2004 Oct; 11(20):1487-96. PubMed ID: 15343360
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Stable therapeutic serum levels of human alpha-1 antitrypsin (AAT) after portal vein injection of recombinant adeno-associated virus (rAAV) vectors.
    Song S; Embury J; Laipis PJ; Berns KI; Crawford JM; Flotte TR
    Gene Ther; 2001 Sep; 8(17):1299-306. PubMed ID: 11571566
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Preclinical characterization of a recombinant adeno-associated virus type 1-pseudotyped vector demonstrates dose-dependent injection site inflammation and dissemination of vector genomes to distant sites.
    Flotte TR; Conlon TJ; Poirier A; Campbell-Thompson M; Byrne BJ
    Hum Gene Ther; 2007 Mar; 18(3):245-56. PubMed ID: 17376008
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.